Search Results - "Benoit‐Vical, Françoise"

Increased Tolerance to Artemisinin in Plasmodium falciparum Is Mediated by a Quiescence Mechanism by WITKOWSKI, Benoit, LELIEVRE, Joel, LOPEZ BARRAGAN, Maria José, LAURENT, Victor, SU, Xin-Zhuan, BERRY, Antoine, BENOIT-VICAL, Françoise

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Synthesis, Structures, and Biological Studies of Heterobimetallic Au(I)–Ru(II) Complexes Involving N‑Heterocyclic Carbene-Based Multidentate Ligands by Boselli, Luca, Carraz, Maëlle, Mazères, Serge, Paloque, Lucie, González, Germán, Benoit-Vical, Françoise, Valentin, Alexis, Hemmert, Catherine, Gornitzka, Heinz

“…Three heterobimetallic gold(I)–ruthenium(II) complexes containing heteroditopic bipyridine–N-heterocyclic carbene (NHC) ligands were synthesized and fully…”
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Reduced Artemisinin Susceptibility of Plasmodium falciparum Ring Stages in Western Cambodia by WITKOWSKI, Benoit, KHIM, Nimol, DONDORP, Arjen M, TRIPURA, Rupam, BENOIT-VICAL, Françoise, BERRY, Antoine, GORGETTE, Olivier, ARIEY, Frédéric, BARALE, Jean-Christophe, MERCEREAU-PUIJALON, Odile, MENARD, Didier, CHIM, Pheaktra, KIM, Saorin, KE, Sopheakvatey, KLOEUNG, Nimol, CHY, Sophy, DUONG, Socheat, LEANG, Rithea, RINGWALD, Pascal

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Superoxide: A major role in the mechanism of action of essential antimalarial drugs by Egwu, Chinedu O., Tsamesidis, Ioannis, Pério, Pierre, Augereau, Jean-Michel, Benoit-Vical, Françoise, Reybier, Karine

“…Understanding the mode of action of antimalarials is central to optimizing their use and the discovery of new therapeutics. Currently used antimalarials belong…”
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Reactive Oxygen Species as the Brainbox in Malaria Treatment by Egwu, Chinedu Ogbonnia, Augereau, Jean-Michel, Reybier, Karine, Benoit-Vical, Françoise

“…Several measures are in place to combat the worldwide spread of malaria, especially in regions of high endemicity. In part, most common antimalarials, such as…”
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In Vitro and In Vivo Properties of Ellagic Acid in Malaria Treatment by NJOMNANG SOH, Patrice, WITKOWSKI, Benoit, OLAGNIER, David, NICOLAU, Marie-Laure, GARCIA-ALVAREZ, Maria-Concepcion, BERRY, Antoine, BENOIT-VICAL, Francoise

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Hybrid Peptide-Alkoxyamine Drugs: A Strategy for the Development of a New Family of Antiplasmodial Drugs by Embo-Ibouanga, Ange W, Nguyen, Michel, Paloque, Lucie, Coustets, Mathilde, Joly, Jean-Patrick, Augereau, Jean-Michel, Vanthuyne, Nicolas, Bikanga, Raphaël, Coquin, Naomie, Robert, Anne, Audran, Gérard, Boissier, Jérôme, Mellet, Philippe, Benoit-Vical, Françoise, Marque, Sylvain R A

“…The emergence and spread of drug-resistant parasites shed a serious concern on the worldwide control of malaria, the most important tropical disease in terms…”
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Induction of Multidrug Tolerance in Plasmodium falciparum by Extended Artemisinin Pressure by Ménard, Sandie, Ben Haddou, Tanila, Ramadani, Arba Pramundita, Ariey, Frédéric, Iriart, Xavier, Beghain, Johann, Bouchier, Christiane, Witkowski, Benoit, Berry, Antoine, Mercereau-Puijalon, Odile, Benoit-Vical, Françoise

“…Plasmodium falciparum resistance to artemisinin derivatives in Southeast Asia threatens global malaria control strategies. Whether delayed parasite clearance,…”
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Concentration and purification by magnetic separation of the erythrocytic stages of all human Plasmodium species by Ribaut, Clotilde, Berry, Antoine, Chevalley, Séverine, Reybier, Karine, Morlais, Isabelle, Parzy, Daniel, Nepveu, Françoise, Benoit-Vical, Françoise, Valentin, Alexis

“…Parasite concentration methods facilitate molecular, biochemical and immunological research on the erythrocytic stages of Plasmodium. In this paper, an…”
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Hybrid Gold(I) NHC-Artemether Complexes to Target Falciparum Malaria Parasites by Ouji, Manel, Barnoin, Guillaume, Fernández Álvarez, Álvaro, Augereau, Jean-Michel, Hemmert, Catherine, Benoit-Vical, Françoise, Gornitzka, Heinz

“…The emergence of parasites, responsible for malaria disease, resistant to antiplasmodial drugs including the artemisinins, represents a major threat to public…”
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Trioxaquines Are New Antimalarial Agents Active on All Erythrocytic Forms, Including Gametocytes by Benoit-Vical, Françoise, Lelièvre, Joël, Berry, Antoine, Deymier, Caroline, Dechy-Cabaret, Odile, Cazelles, Jérôme, Loup, Christophe, Robert, Anne, Magnaval, Jean-François, Meunier, Bernard

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Synthesis and Antimalarial Activities of New Hybrid Atokel Molecules by Li, Youzhi, Loureiro, Anthony, Nguyen, Michel, Laurent, Marion, Bijani, Christian, Benoit‐Vical, Françoise, Robert, Anne, Liu, Yan, Meunier, Bernard

“…The currently spreading resistance of the malaria parasite Plasmodium falciparum to artemisinin‐based combination therapies makes an urgent need for new…”
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Molecular surveillance of Plasmodium falciparum resistance to artemisinin-based combination therapies in the Democratic Republic of Congo by Mvumbi, Dieudonné Makaba, Bobanga, Thierry Lengu, Kayembe, Jean-Marie Ntumba, Mvumbi, Georges Lelo, Situakibanza, Hippolyte Nani-Tuma, Benoit-Vical, Françoise, Melin, Pierrette, De Mol, Patrick, Hayette, Marie-Pierre

“…Malaria is a major public health problem in the Democratic Republic of Congo. Despite progress achieved over the past decade in the fight against malaria,…”
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Epidrugs as Promising Tools to Eliminate Plasmodium falciparum Artemisinin-Resistant and Quiescent Parasites by Reyser, Thibaud, Paloque, Lucie, Nguyen, Michel, Augereau, Jean-Michel, Fuchter, Matthew John, Lopez, Marie, Arimondo, Paola B., Hassell-Hart, Storm, Spencer, John, Di Stefano, Luisa, Benoit-Vical, Françoise

“…The use of artemisinin and its derivatives has helped reduce the burden of malaria caused by Plasmodium falciparum. However, artemisinin-resistant parasites…”
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Alkoxyamines Designed as Potential Drugs against Plasmodium and Schistosoma Parasites by Reyser, Thibaud, To, Tung H, Egwu, Chinedu, Paloque, Lucie, Nguyen, Michel, Hamouy, Alexandre, Stigliani, Jean-Luc, Bijani, Christian, Augereau, Jean-Michel, Joly, Jean-Patrick, Portela, Julien, Havot, Jeffrey, Marque, Sylvain R A, Boissier, Jérôme, Robert, Anne, Benoit-Vical, Françoise, Audran, Gérard

“…Malaria and schistosomiasis are major infectious causes of morbidity and mortality in the tropical and sub-tropical areas. Due to the widespread drug…”
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Nrf2, a PPARγ alternative pathway to promote CD36 expression on inflammatory macrophages: implication for malaria by Olagnier, David, Lavergne, Rose-Anne, Meunier, Etienne, Lefèvre, Lise, Dardenne, Christophe, Aubouy, Agnès, Benoit-Vical, Françoise, Ryffel, Bernhard, Coste, Agnès, Berry, Antoine, Pipy, Bernard

“…CD36 is the major receptor mediating nonopsonic phagocytosis of Plasmodium falciparum-parasitized erythrocytes by macrophages. Its expression on macrophages is…”
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The Antimalarial Drug Artemisinin Alkylates Heme in Infected Mice by Robert, Anne, Benoit-Vical, Françoise, Claparols, Catherine, Meunier, Bernard, Lehn, Jean-Marie P.

“…Heme alkylation by the antimalarial drug artemisinin is reported in vivo, within infected mice that have been treated at pharmacologically relevant doses…”
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Implication of glutathione in the in vitro antiplasmodial mechanism of action of ellagic acid by Njomnang Soh, Patrice, Witkowski, Benoit, Gales, Amandine, Huyghe, Eric, Berry, Antoine, Pipy, Bernard, Benoit-Vical, Françoise

“…The search for new antimalarial chemotherapy has become increasingly urgent due to parasite resistance to current drugs. Ellagic acid (EA) is a polyphenol,…”
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Trioxaquines and Heme-Artemisinin Adducts Inhibit the In Vitro Formation of Hemozoin Better than Chloroquine by Loup, Christophe, Lelièvre, Joël, Benoit-Vical, Françoise, Meunier, Bernard

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Young Sprague Dawley rats infected by Plasmodium berghei: A relevant experimental model to study cerebral malaria by Keita Alassane, Sokhna, Nicolau-Travers, Marie-Laure, Menard, Sandie, Andreoletti, Olivier, Cambus, Jean-Pierre, Gaudre, Noémie, Wlodarczyk, Myriam, Blanchard, Nicolas, Berry, Antoine, Abbes, Sarah, Colongo, David, Faye, Babacar, Augereau, Jean-Michel, Lacroux, Caroline, Iriart, Xavier, Benoit-Vical, Françoise

“…Cerebral malaria (CM) is the most severe manifestation of human malaria yet is still poorly understood. Mouse models have been developed to address the…”
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