Search Results - "Benoist, Lauriane"
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P2Y11 Agonism Prevents Hypoxia/Reoxygenation- and Angiotensin II-Induced Vascular Dysfunction and Intimal Hyperplasia Development
Published in International journal of molecular sciences (16-01-2021)“…Vascular dysfunction in cardiovascular diseases includes vasomotor response impairments, endothelial cells (ECs) activation, and smooth muscle cells (SMCs)…”
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NaV1.5 sodium channels allosterically regulate the NHE-1 exchanger and promote breast cancer cell invadopodial activity
Published in Journal of cell science (01-01-2013)“…The degradation of the extracellular matrix by cancer cells represents an essential step in metastatic progression and this is performed by cancer cell…”
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Stimulation of murine P2Y11-like purinoreceptor protects against hypoxia/reoxygenation injury and decreases heart graft rejection lesions
Published in The Journal of thoracic and cardiovascular surgery (01-09-2019)“…Myocardial ischemia reperfusion is a major cause of cell injury during cardiac transplantation and is responsible for increased graft rejection. Several…”
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NaV1.5 Na⁺ channels allosterically regulate the NHE-1 exchanger and promote the activity of breast cancer cell invadopodia
Published in Journal of cell science (01-11-2013)“…The degradation of the extracellular matrix by cancer cells represents an essential step in metastatic progression and this is performed by cancer cell…”
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Stimulation of P2Y11 receptor modulates cardiac fibroblasts secretome toward immunomodulatory and protective roles after Hypoxia/Reoxygenation injury
Published in Journal of molecular and cellular cardiology (01-08-2018)“…Cardiac fibroblasts are important regulators of myocardial structure and function. Their implications in pathological processes such as Ischemia/Reperfusion…”
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IMPROVEMENT OF VASCULAR RESPONSE TO ISCHEMIA/REPERFUSION INJURY: ROLE OF THE P2Y11 PURINERGIC RECEPTOR
Published in Journal of the American College of Cardiology (12-03-2019)Get full text
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Stimulation of P2Y11 receptor protects human cardiomyocytes against Hypoxia/Reoxygenation injury and involves PKCε signaling pathway
Published in Scientific reports (12-08-2019)“…Sterile inflammation is a key determinant of myocardial reperfusion injuries. It participates in infarct size determination in acute myocardial infarction and…”
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Hypoxia/Reoxygenation Inhibits P2Y11 Receptor Expression and Its Immunosuppressive Activity in Human Dendritic Cells
Published in The Journal of immunology (1950) (15-07-2015)“…High concentrations of extracellular ATP (eATP) resulting from cell damage may be found during an ischemia/reperfusion (I/R) episode at the site of injury…”
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NaV1.5 sodium channels increase breast cancer cell invadopodial activity by both controlling Src kinase-dependent F-actin polymerization and promoting NHE-1-dependent proton efflux and extracellular matrix digestion
Published in Frontiers in pharmacology (2014)“…Abstract only…”
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Abstract 15001: Stimulation of P2Y11 Receptor Affords Cardioprotection Against Hypoxia/Reoxygenation Injury in Cultured Cardiomyocytes and Improves Allogeneic Heart Graft Survival
Published in Circulation (New York, N.Y.) (11-11-2016)“…Ischemia reperfusion injuries are involved in the physiopathology of heart transplantation where they will increase graft rejection. Ischemia generates…”
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