Search Results - "Benny Klimek, Margaret"

Effect of the IL-1 Receptor Antagonist Kineret® on Disease Phenotype in mdx Mice by Benny Klimek, Margaret E, Sali, Arpana, Rayavarapu, Sree, Van der Meulen, Jack H, Nagaraju, Kanneboyina

“…Duchenne muscular dystrophy (DMD) is an X-linked muscle disease caused by mutations in the dystrophin gene. The pathology of DMD manifests in patients with…”
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Acute inhibition of myostatin-family proteins preserves skeletal muscle in mouse models of cancer cachexia by Benny Klimek, Margaret E., Aydogdu, Tufan, Link, Majik J., Pons, Marianne, Koniaris, Leonidas G., Zimmers, Teresa A.

“…Cachexia, progressive loss of fat and muscle mass despite adequate nutrition, is a devastating complication of cancer associated with poor quality of life and…”
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Morpholino‐induced exon skipping stimulates cell‐mediated and humoral responses to dystrophin in mdx mice by Vila, Maria C, Novak, James S, Benny Klimek, Margaret, Li, Ning, Morales, Melissa, Fritz, Alexander G, Edwards, Katie, Boehler, Jessica F, Hogarth, Marshall W, Kinder, Travis B, Zhang, Aiping, Mazala, Davi, Fiorillo, Alyson A, Douglas, Bonnie, Chen, Yi‐Wen, van den Anker, John, Lu, Qi L, Hathout, Yetrib, Hoffman, Eric P, Partridge, Terence A, Nagaraju, Kanneboyina

“…Exon skipping is a promising genetic therapeutic strategy for restoring dystrophin expression in the treatment of Duchenne muscular dystrophy (DMD). The…”
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Inhibition of inflammation with celastrol fails to improve muscle function in dysferlin-deficient A/J mice by Dillingham, Blythe C, Benny Klimek, Margaret E, Gernapudi, Ramkishore, Rayavarapu, Sree, Gallardo, Eduard, Van der Meulen, Jack H, Jordan, Sarah, Ampong, Beryl, Gordish-Dressman, Heather, Spurney, Christopher F, Nagaraju, Kanneboyina

“…Abstract The dysferlin-deficient A/J mouse strain represents a homologous model for limb-girdle muscular dystrophy 2B. We evaluated the disease phenotype in 10…”
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Effects of Chronic, Maximal Phosphorodiamidate Morpholino Oligomer (PMO) Dosing on Muscle Function and Dystrophin Restoration in a Mouse Model of Duchenne Muscular Dystrophy by Benny Klimek, Margaret E, Vila, Maria Candida, Edwards, Katie, Boehler, Jessica, Novak, James, Zhang, Aiping, Van der Meulen, Jack, Tatum, Kathleen, Quinn, James, Fiorillo, Alyson, Burki, Umar, Straub, Volker, Lu, Qi Long, Hathout, Yetrib, van Den Anker, John, Partridge, Terence A, Morales, Melissa, Hoffman, Eric, Nagaraju, Kanneboyina

“…Phosphorodiamidate morpholino oligomer (PMO)-mediated exon skipping is currently used in clinical development to treat Duchenne muscular dystrophy (DMD), with…”
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Effect of the IL-1 Receptor Antagonist Kineret.sup.® on Disease Phenotype in mdx Mice by Benny Klimek, Margaret E, Sali, Arpana, Rayavarapu, Sree, Van der Meulen, Jack H, Nagaraju, Kanneboyina

“…Duchenne muscular dystrophy (DMD) is an X-linked muscle disease caused by mutations in the dystrophin gene. The pathology of DMD manifests in patients with…”
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Elusive sources of variability of dystrophin rescue by exon skipping by Vila, Maria Candida, Klimek, Margaret Benny, Novak, James S, Rayavarapu, Sree, Uaesoontrachoon, Kitipong, Boehler, Jessica F, Fiorillo, Alyson A, Hogarth, Marshall W, Zhang, Aiping, Shaughnessy, Conner, Gordish-Dressman, Heather, Burki, Umar, Straub, Volker, Lu, Qi Long, Partridge, Terence A, Brown, Kristy J, Hathout, Yetrib, van den Anker, John, Hoffman, Eric P, Nagaraju, Kanneboyina

“…Systemic delivery of anti-sense oligonucleotides to Duchenne muscular dystrophy (DMD) patients to induce de novo dystrophin protein expression in muscle (exon…”
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Molecular mechanisms of heart valve and skeletal muscle development and disease by Benny Klimek, Margaret E

“…Heart valves function to provide unidirectional blood flow during each cardiac cycle. The development of the heart valves from embryonic stages is a highly…”
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Abstract 5101: Acute inhibition of myostatin-family proteins preserves muscle in cancer cachexia by Klimek, Margaret E. Benny, Aydogdu, Tufan, Link, Majik, Pons, Marianne, Koniaris, Leonidas G., Zimmers, Teresa A.

“…Cachexia, progressive loss of fat and muscle mass despite adequate nutrition, is a devastating complication of cancer associated with poor quality of life and…”
Get full text

Molecular mechanisms of heart valve and skeletal muscle development and disease by Benny Klimek, Margaret E

“…Heart valves function to provide unidirectional blood flow during each cardiac cycle. The development of the heart valves from embryonic stages is a highly…”
Get full text