Search Results - "Bennink, H J"

The effect of combined oral contraception on testosterone levels in healthy women: a systematic review and meta-analysis by Zimmerman, Y, Eijkemans, M J C, Coelingh Bennink, H J T, Blankenstein, M A, Fauser, B C J M

“…BACKGROUND; Combined oral contraceptives (COCs) reduce levels of androgen, especially testosterone (T), by inhibiting ovarian and adrenal androgen synthesis…”
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A few certainties about testosterone in women by Coelingh Bennink, H. J. T.

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Progesterone and not estrogens or androgens causes breast cancer by Coelingh Bennink, H J T, Stanczyk, F Z

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Pharmacokinetics of the fetal estrogen estetrol in a multiple-rising-dose study in postmenopausal women by Coelingh Bennink, H J T, Verhoeven, C, Zimmerman, Y, Visser, M, Foidart, J-M, Gemzell-Danielsson, K

“…Estetrol (E4) is a natural fetal estrogen. In this open-label, multiple-rising-dose study, the pharmacokinetic effects of E4 in postmenopausal women were…”
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Estetrol review: profile and potential clinical applications by Coelingh Bennink, H. J. T., Holinka, C. F., Diczfalusy, E.

“…In this review paper, the existing information on the human fetal steroid estetrol (E4) has been summarized. In the past, E4 was considered as a weak estrogen…”
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In vitro effects of estetrol on receptor binding, drug targets and human liver cell metabolism by Visser, M., Foidart, J.-M., Coelingh Bennink, H. J. T.

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Restoring testosterone levels by adding dehydroepiandrosterone to a drospirenone containing combined oral contraceptive: I. Endocrine effects by Zimmerman, Y, Foidart, J.-M, Pintiaux, A, Minon, J.-M, Fauser, B.C.J.M, Cobey, K, Coelingh Bennink, H.J.T

“…Abstract Objectives Combined oral contraceptives (COCs) decrease testosterone (T) levels. This study investigated restoration of T and other androgen…”
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Oral bioavailability and bone-sparing effects of estetrol in an osteoporosis model by Coelingh Bennink, H. J. T., Heegaard, A.-M., Visser, M., Holinka, C. F., Christiansen, C.

“…Objectives To measure the oral bioavailability of estetrol (E4) in rats relative to its subcutaneous administration and to test the bone-sparing effect of oral…”
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Estetrol does not bind sex hormone binding globulin or increase its production by human HepG2 cells by Hammond, G. L., Hogeveen, K. N., Visser, M., Coelingh Bennink, H. J. T.

“…Objectives To determine whether human sex hormone binding globulin (SHBG) binds estetrol (E4), and to assess whether E4 stimulates the production of SHBG by…”
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First human exposure to exogenous single-dose oral estetrol in early postmenopausal women by Visser, M., Holinka, C. F., Coelingh Bennink, H. J. T.

“…Objective To evaluate the safety, tolerability, pharmacokinetics and effect on gonadotropins of a single escalating dose of estetrol (E4). Methods A…”
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Preventive effect of oral estetrol in a menopausal hot flush model by Holinka, C. F., Brincat, M., Coelingh Bennink, H. J. T.

“…Objective To evaluate the efficacy of estetrol (E4) in alleviating hot flushes in an experimental animal model considered representative for menopausal…”
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Estrogenic uterovaginal effects of oral estetrol in the modified Allen-Doisy test by Heegaard, A.-M., Holinka, C. F., Kenemans, P., Coelingh Bennink, H. J. T.

“…Objective To evaluate the effect of estetrol (E4) on vaginal cornification and uterine wet weight in the ovariectomized rat. Methods Adult female rats served…”
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Maternal and fetal estetrol levels during pregnancy by Coelingh Bennink, F., Holinka, C. F., Visser, M., Coelingh Bennink, H. J. T.

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Estetrol: A unique steroid in human pregnancy by Holinka, C. F., Diczfalusy, E., Coelingh Bennink, H. J. T.

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Estetrol, a pregnancy-specific human steroid, prevents and suppresses mammary tumor growth in a rat model by Coelingh Bennink, H. J. T., Singer, C., Simoncini, T., Genazzani, A. R., Holinka, C. F., Kubista, E.

“…Estetrol (E4) is a pregnancy-specific D-ring metabolite of estradiol (E2) and estriol (E3) produced by the human fetal liver and present in both male and…”
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Ovulation inhibition by estetrol in an in vivo model by Coelingh Bennink, H. J. T., Skouby, S., Bouchard, P., Holinka, C. F.

“…Background Currently, the synthetic steroid ethinylestradiol is the preferred estrogen in combined oral contraceptives. The aim of the present study was to…”
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A new route of synthesis of estetrol by Warmerdam, E. G. J. C., Visser, M., Coelingh Bennink, H. J. T., Groen, M.

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FSH and ovarian response: spontaneous recovery of pituitary-ovarian activity during the pill-free period vs. exogenous recombinant FSH during high-dose combined oral contraceptives by Van Heusden, A. M., Coelingh Bennink, H. J. T., Fauser, B. C. J. M.

“…Summary ojbective Compare spontaneous recovery of pituitary–ovarian activity during the pill‐free period following the correct use of low‐dose oral…”
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Detection of cervical neoplasia by DNA methylation analysis in cervico-vaginal lavages, a feasibility study by Eijsink, J.J.H, Yang, N, Lendvai, A, Klip, H.G, Volders, H.H, Buikema, H.J, van Hemel, B.M, Voll, M, Bennink, H.J.T. Coelingh, Schuuring, E, Wisman, G.B.A, van der Zee, A.G.J

“…Abstract Objective To explore the feasibility of DNA methylation analysis for the detection of cervical neoplasia in self-obtained cervico-vaginal lavages…”
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High dose gonadotrophin-releasing hormone antagonist (ganirelix) may prevent ovarian hyperstimulation syndrome caused by ovarian stimulation for in-vitro fertilization by de Jong, D, Macklon, N S, Mannaerts, B M, Coelingh Bennink, H J, Fauser, B C

“…This case report describes the first attempt to treat imminent ovarian hyperstimulation syndrome (OHSS) by using a gonadotrophin-releasing hormone (GnRH)…”
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