Search Results - "Benning, Matthew M"

High Resolution X-ray Structures of Different Metal-Substituted Forms of Phosphotriesterase from Pseudomonas diminuta by Benning, Matthew M, Shim, Hyunbo, Raushel, Frank M, Holden, Hazel M

“…Phosphotriesterase, isolated from the soil-dwelling bacterium Pseudomonas diminuta, catalyzes the detoxification of organophosphate-based insecticides and…”
Get full text

Three-Dimensional Structure of Phosphotriesterase: An Enzyme Capable of Detoxifying Organophosphate Nerve Agents by Benning, Matthew M, Kuo, Jane M, Raushel, Frank M, Holden, Hazel M

“…Organophosphates, such as parathion and paraoxon, constitute the largest class of insecticides currently used in industrialized nations. In addition, many of…”
Get full text

Molecular structure of an N‐formyltransferase from Providencia alcalifaciens O30 by Genthe, Nicholas A., Thoden, James B., Benning, Matthew M., Holden, Hazel M.

“…The existence of N‐formylated sugars in the O‐antigens of Gram‐negative bacteria has been known since the middle 1980s, but only recently have the biosynthetic…”
Get full text

Molecular Structure of the Rat Vitamin D Receptor Ligand Binding Domain Complexed with 2-Carbon-Substituted Vitamin D3 Hormone Analogues and a LXXLL-Containing Coactivator Peptide by Vanhooke, Janeen L, Benning, Matthew M, Bauer, Cary B, Pike, J. Wesley, DeLuca, Hector F

“…We have determined the crystal structures of the ligand binding domain (LBD) of the rat vitamin D receptor in ternary complexes with a synthetic…”
Get full text

Divergence of Chemical Function in the Alkaline Phosphatase Superfamily: Structure and Mechanism of the P−C Bond Cleaving Enzyme Phosphonoacetate Hydrolase by Kim, Alexander, Benning, Matthew M, OkLee, Sang, Quinn, John, Martin, Brian M, Holden, Hazel M, Dunaway-Mariano, Debra

“…Phosphonates constitute a class of natural products that mimic the properties of the more common organophosphate ester metabolite yet are not readily degraded…”
Get full text

Structure−Function Relationships in Anabaena Ferredoxin:  Correlations between X-ray Crystal Structures, Reduction Potentials, and Rate Constants of Electron Transfer to Ferredoxin:NADP+ Reductase for Site-Specific Ferredoxin Mutants by Hurley, John K, Weber-Main, Anne M, Stankovich, Marian T, Benning, Matthew M, Thoden, James B, Vanhooke, Janeen L, Holden, Hazel M, Chae, Young Kee, Xia, Bin, Cheng, Hong, Markley, John L, Martinez-Júlvez, Marta, Gómez-Moreno, Carlos, Schmeits, James L, Tollin, Gordon

“…A combination of structural, thermodynamic, and transient kinetic data on wild-type and mutant Anabaena vegetative cell ferredoxins has been used to…”
Get full text

New analogs of 2-methylene-19-nor-(20S)-1,25-dihydroxyvitamin D3 with conformationally restricted side chains: Evaluation of biological activity and structural determination of VDR-bound conformations by Vanhooke, Janeen L., Tadi, Bulli Padmaja, Benning, Matthew M., Plum, Lori A., DeLuca, Hector F.

“…We have successfully prepared E- and Z- isomers of 17–20 dehydro analogs of 2-methylene-19-nor-(20S)-1α,25-dihydroxyvitamin D3 (2MD). Both isomers bind to the…”
Get full text

The Crotonase Superfamily:  Divergently Related Enzymes That Catalyze Different Reactions Involving Acyl Coenzyme A Thioesters by Holden, Hazel M, Benning, Matthew M, Haller, Toomas, Gerlt, John A

“…Synergistic investigations of the reactions catalyzed by several members of an enzyme superfamily provide a more complete understanding of the relationships…”
Get full text

Molecular Structure of the Oxidized High-Potential Iron-Sulfur Protein Isolated from Ectothiorhodospira vacuolata by Benning, Matthew M, Meyer, Terrance E, Rayment, Ivan, Holden, Hazel M

“…The high-potential iron-sulfur protein (iso-form II) isolated from Ectothiorhodospira vacuolata has been crystallized and its three-dimensional structure…”
Get full text

Three-Dimensional Structure of Myosin Subfragment-1: A Molecular Motor by Rayment, Ivan, Rypniewski, Wojciech R., Schmidt-Bäse, Karen, Smith, Robert, Tomchick, Diana R., Benning, Matthew M., Winkelmann, Donald A., Wesenberg, Gary, Holden, Hazel M.

“…Directed movement is a characteristic of many living organisms and occurs as a result of the transformation of chemical energy into mechanical energy. Myosin…”
Get full text

Crystal structure of Npun_R1517, a putative negative regulator of heterocyst differentiation from Nostoc punctiforme PCC 73102 by Ni, Shuisong, Benning, Matthew M., Smola, Matthew J., Feldmann, Erik A., Kennedy, Michael A.

Get full text

Three-Dimensional Structure of the Zinc-Containing Phosphotriesterase with the Bound Substrate Analog Diethyl 4-Methylbenzylphosphonate by Vanhooke, Janeen L, Benning, Matthew M, Raushel, Frank M, Holden, Hazel M

“…Phosphotriesterase from Pseudomonas diminuta catalyzes the hydrolysis of paraoxon and related acetylcholinesterase inhibitors with rate enhancements that…”
Get full text

Structure of the Bis(Mg2+)−ATP−Oxalate Complex of the Rabbit Muscle Pyruvate Kinase at 2.1 Å Resolution:  ATP Binding over a Barrel by Larsen, Todd M, Benning, Matthew M, Rayment, Ivan, Reed, George H

“…Pyruvate kinase from rabbit muscle has been cocrystallized as a complex with MgIIATP, oxalate, Mg2+, and either K+ or Na+. Crystals with either Na+ or K+…”
Get full text

The Binding of Substrate Analogs to Phosphotriesterase by Benning, Matthew M., Hong, Suk-Bong, Raushel, Frank M., Holden, Hazel M.

“…Phosphotriesterase (PTE) from Pseudomonas diminuta catalyzes the detoxification of organophosphates such as the widely utilized insecticide paraoxon and the…”
Get full text

Three-dimensional structure of the binuclear metal center of phosphotriesterase by Benning, Matthew M, Kuo, Jane M, Raushel, Frank M, Holden, Hazel M

“…Phosphotriesterase, as isolated from Pseudomonas diminuta, is capable of detoxifying widely used pesticides such as paraoxon and parathion and various…”
Get full text

New Reactions in the Crotonase Superfamily:  Structure of Methylmalonyl CoA Decarboxylase from Escherichia coli by Benning, Matthew M, Haller, Toomas, Gerlt, John A, Holden, Hazel M

“…The molecular structure of methylmalonyl CoA decarboxylase (MMCD), a newly defined member of the crotonase superfamily encoded by the Escherichia coli genome,…”
Get full text

The Three-dimensional Structure of 4-Hydroxybenzoyl-CoA Thioesterase from Pseudomonas sp. Strain CBS-3 by Benning, M M, Wesenberg, G, Liu, R, Taylor, K L, Dunaway-Mariano, D, Holden, H M

“…The soil-dwelling microbe, Pseudomonas sp. strain CBS-3, has attracted recent attention due to its ability to survive on 4-chlorobenzoate as its sole carbon…”
Get full text

Structure of 4-Chlorobenzoyl Coenzyme A Dehalogenase Determined to 1.8 Å Resolution:  An Enzyme Catalyst Generated via Adaptive Mutation by Benning, Matthew M, Taylor, Kimberly L, Liu, Rui-Qin, Yang, Guang, Xiang, Hong, Wesenberg, Gary, Dunaway-Mariano, Debra, Holden, Hazel M

“…Here we describe the three-dimensional structure of 4-chlorobenzoyl-CoA dehalogenase from Pseudomonas sp. strain CBS-3. This enzyme catalyzes the hydrolysis of…”
Get full text

f-Element/crown ether complexes. 22. Preparation and structural characterization of lanthanide chloride complexes of 12-crown-4 by Rogers, Robin D, Rollins, Andrew N, Benning, Matthew M

Get full text

Next-generation home-lab systems for the changing structural biology landscape by Benning, Matthew M., Mrosek, Michael

“…Abstract only…”
Get full text