Search Results - "Bennett Saidu, Nathaniel Edward"

Dimethyl fumarate, a two‐edged drug: Current status and future directions by Saidu, Nathaniel Edward Bennett, Kavian, Niloufar, Leroy, Karen, Jacob, Claus, Nicco, Carole, Batteux, Frédéric, Alexandre, Jérôme

“…Dimethyl fumarate (DMF) is a fumaric acid ester registered for the treatment of relapsing‐remitting multiple sclerosis (RRMS). It induces protein succination…”
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The NRF2 transcriptional target NQO1 has low mRNA levels in TP53-mutated endometrial carcinomas by Beinse, Guillaume, Just, Pierre-Alexandre, Rance, Bastien, Izac, Brigitte, Letourneur, Franck, Saidu, Nathaniel Edward Bennett, Chouzenoux, Sandrine, Nicco, Carole, Goldwasser, François, Pasmant, Eric, Batteux, Frederic, Borghese, Bruno, Alexandre, Jérôme, Leroy, Karen

“…NRF2 is a major transcription factor regulating the expression of antioxidative/detoxifying enzymes, involved in oncogenic processes and drug resistance. We…”
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Dimethyl fumarate is highly cytotoxic in KRAS mutated cancer cells but spares non-tumorigenic cells by Bennett Saidu, Nathaniel Edward, Bretagne, Marie, Mansuet, Audrey Lupo, Just, Pierre-Alexandre, Leroy, Karen, Cerles, Olivier, Chouzenoux, Sandrine, Nicco, Carole, Damotte, Diane, Alifano, Marco, Borghese, Bruno, Goldwasser, François, Batteux, Frédéric, Alexandre, Jérôme

“…KRAS mutation, one of the most common molecular alterations observed in adult carcinomas, was reported to activate the anti-oxidant program driven by the…”
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HPV Oncoproteins and the Ubiquitin Proteasome System: A Signature of Malignancy? by Đukić, Anamaria, Lulić, Lucija, Thomas, Miranda, Skelin, Josipa, Bennett Saidu, Nathaniel Edward, Grce, Magdalena, Banks, Lawrence, Tomaić, Vjekoslav

“…Human papillomavirus (HPV) E6 and E7 oncoproteins are critical for development and maintenance of the malignant phenotype in HPV-induced cancers. These two…”
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Preventive action of benztropine on platinum-induced peripheral neuropathies and tumor growth by Cerles, Olivier, Gonçalves, Tânia Cristina, Chouzenoux, Sandrine, Benoit, Evelyne, Schmitt, Alain, Bennett Saidu, Nathaniel Edward, Kavian, Niloufar, Chéreau, Christiane, Gobeaux, Camille, Weill, Bernard, Coriat, Romain, Nicco, Carole, Batteux, Frédéric

“…The endogenous cholinergic system plays a key role in neuronal cells, by suppressing neurite outgrowth and myelination and, in some cancer cells, favoring…”
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IUIS 2023: yEFIS workshop on career development and code‐switching by Kempkes, Rosalie W M, Nikolaou, Christos, Nabhan, Myriam, Saidu, Nathaniel Edward Bennett

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New Approaches for the Treatment of Chronic Graft-Versus-Host Disease: Current Status and Future Directions by Saidu, Nathaniel Edward Bennett, Bonini, Chiara, Dickinson, Anne, Grce, Magdalena, Inngjerdingen, Marit, Koehl, Ulrike, Toubert, Antoine, Zeiser, Robert, Galimberti, Sara

“…Chronic graft-versus-host disease (cGvHD) is a severe complication of allogeneic hematopoietic stem cell transplantation that affects various organs leading to…”
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Identifying a core protein signature of small extracellular vesicles derived from B‐cell precursor acute lymphoblastic leukaemia by Saidu, Nathaniel Edward Bennett, Aarsund, Miriam, Sørensen, Eva, Stensland, Maria, Nyman, Tuula Anneli, Ulvmoen, Aina, Wu, Yunjie, Inngjerdingen, Marit

“…Acute paediatric leukaemia is diagnosed and monitored via bone marrow aspirate assessment of blasts as a measure of minimal residual disease. Liquid biopsies…”
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Coumarin polysulfides inhibit cell growth and induce apoptosis in HCT116 colon cancer cells by Saidu, Nathaniel Edward Bennett, Valente, Sergio, Bana, Emilie, Kirsch, Gilbert, Bagrel, Denyse, Montenarh, Mathias

“…Coumarins and coumarin derivatives as well as diallyl polysulfides are well known as anticancer drugs. In order to find new drugs with anticancer activities,…”
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The Nrf2 -Antioxidant Response Element Signaling Pathway Controls Fibrosis and Autoimmunity in Scleroderma by Kavian, Niloufar, Mehlal, Souad, Jeljeli, Mohamed, Saidu, Nathaniel Edward Bennett, Nicco, Carole, Cerles, Olivier, Chouzenoux, Sandrine, Cauvet, Anne, Camus, Claire, Ait-Djoudi, Mehdi, Chéreau, Christiane, Kerdine-Römer, Saadia, Allanore, Yannick, Batteux, Frederic

“…Systemic sclerosis (SSc) is an autoimmune disease with fibrosis of the skin and internal organs and vascular alterations. Dysregulations in the…”
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Dimethyl Fumarate Controls the NRF2/DJ-1 Axis in Cancer Cells: Therapeutic Applications by Saidu, Nathaniel Edward Bennett, Noé, Gaëlle, Cerles, Olivier, Cabel, Luc, Kavian-Tessler, Niloufar, Chouzenoux, Sandrine, Bahuaud, Mathilde, Chéreau, Christiane, Nicco, Carole, Leroy, Karen, Borghese, Bruno, Goldwasser, François, Batteux, Frédéric, Alexandre, Jérôme

“…The transcription factor NRF2 (NFE2L2), regulates important antioxidant and cytoprotective genes. It enhances cancer cell proliferation and promotes…”
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Identification of TP53 mutated group using a molecular and immunohistochemical classification of endometrial carcinoma to improve prognostic evaluation for adjuvant treatments by Beinse, Guillaume, Rance, Bastien, Just, Pierre-Alexandre, Izac, Brigitte, Letourneur, Franck, Saidu, Nathaniel Edward Bennett, Chouzenoux, Sandrine, Nicco, Carole, Goldwasser, François, Batteux, Frederic, Durdux, Catherine, Chapron, Charles, Pasmant, Eric, Leroy, Karen, Alexandre, Jerome, Borghese, Bruno

“…Molecular classification of endometrial carcinoma has been proposed to predict survival. However, its role in patient management remains to be determined. We…”
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Corrigendum: The Nrf2-Antioxidant Response Element Signaling Pathway Controls Fibrosis and Autoimmunity in Scleroderma by Kavian, Niloufar, Mehlal, Souad, Jeljeli, Mohamed, Saidu, Nathaniel Edward Bennett, Nicco, Carole, Cerles, Olivier, Chouzenoux, Sandrine, Cauvet, Anne, Camus, Claire, Ait-Djoudi, Mehdi, Chéreau, Christiane, Kerdine-Römer, Saadia, Allanore, Yannick, Batteux, Frederic

“…Abstract The skin is frequently exposed to chemical stress by organic chemicals or metal ions that can directly or indirectly challenge its immune components…”
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ER stress signaling in ARPE-19 cells after inhibition of protein kinase CK2 by CX-4945 by Intemann, Johanna, Saidu, Nathaniel Edward Bennett, Schwind, Lisa, Montenarh, Mathias

“…Protein kinase CK2 is a critical factor for the survival of cells. It is overexpressed in many cancer cells and provides protection against apoptosis in these…”
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Identifying a core protein signature of small extracellular vesicles derived from B-cell precursor acute lymphoblastic leukaemia by Saidu, Nathaniel Edward Bennett, Larsen, Miriam Aarsund, Sørensen, Eva, Stensland, Maria, Nyman, Tuula Anneli, Ulvmoen, Aina, Wu, Yunjie, Inngjerdingen, Marit

“…Abstract Acute paediatric leukaemia is diagnosed and monitored via bone marrow aspirate assessment of blasts as a measure of minimal residual disease. Liquid…”
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PDZ Domain-Containing Protein NHERF-2 Is a Novel Target of Human Papillomavirus 16 (HPV-16) and HPV-18 by Saidu, Nathaniel Edward Bennett, Filić, Vedrana, Thomas, Miranda, Sarabia-Vega, Vanessa, Đukić, Anamaria, Miljković, Frane, Banks, Lawrence, Tomaić, Vjekoslav

“…Cancer-causing human papillomavirus (HPV) E6 oncoproteins have a class I PDZ-binding motif (PBM) on their C termini, which play critical roles that are related…”
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Comparison between the effects of diallyl tetrasulfide on human retina pigment epithelial cells (ARPE-19) and HCT116 cells by Saidu, Nathaniel Edward Bennett, Abu Asali, Imad, Czepukojc, Brigitte, Seitz, Berthold, Jacob, Claus, Montenarh, Mathias

“…Diallyl mono- and polysulfanes from garlic are known to induce an adaptive cell response and the formation of antioxidants in cancer cells. In the case of a…”
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A new tellurium-containing amphiphilic molecule induces apoptosis in HCT116 colon cancer cells by Du, Peng, Saidu, Nathaniel Edward Bennett, Intemann, Johanna, Jacob, Claus, Montenarh, Mathias

“…Chalcogen-based redox modulators over the years have attracted considerable attention as anti-cancer agents. New selenium- and tellurium-containing compounds…”
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Diallyl tetrasulfane activates both the eIF2α and Nrf2/HO-1 pathways by Saidu, Nathaniel Edward Bennett, Touma, Rania, Asali, Imad Abu, Jacob, Claus, Montenarh, Mathias

“…Diallyl polysulfanes have been shown to exert cell cycle arrest, anti-tumor and anti-inflammatory activities in a variety of in vitro and in vivo models…”
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