Search Results - "Bennett, Seth A"

Epigenetics in amyotrophic lateral sclerosis: a role for histone post-translational modifications in neurodegenerative disease by Bennett, Seth A., Tanaz, Royena, Cobos, Samantha N., Torrente, Mariana P.

“…Amyotrophic lateral sclerosis (ALS) is the third most common adult onset neurodegenerative disorder worldwide. It is generally characterized by progressive…”
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[PRION + ] States Are Associated with Specific Histone H3 Post-Translational Modification Changes by Cobos, Samantha N, Janani, Chaim, Cruz, Gabriel, Rana, Navin, Son, Elizaveta, Frederic, Rania, Paredes Casado, Jailene, Khan, Maliha, Bennett, Seth A, Torrente, Mariana P

“…Prions are proteins able to take on alternative conformations and propagate them in a self-templating process. In , prions enable heritable responses to…”
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The impact of histone post-translational modifications in neurodegenerative diseases by Cobos, Samantha N., Bennett, Seth A., Torrente, Mariana P.

“…Every year, neurodegenerative disorders take more than 5000 lives in the US alone. Cures have not yet been found for many of the multitude of neuropathies. The…”
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Mapping Out Histone Post‐Translational Modifications in a Yeast Prion Model by Cobos, Samantha N., Son, Elizaveta, Paredes, Jailene, Rana, Navin, Bennett, Seth A., Torrente, Mariana P.

“…Prions are proteins with the ability to self‐template into alternative folds, allowing them to operate outside the canonical steps of the central dogma of…”
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Trichostatin A Relieves Growth Suppression and Restores Histone Acetylation at Specific Sites in a FUS ALS/FTD Yeast Model by Bennett, Seth A, Cobos, Samantha N, Mirzakandova, Melagras, Fallah, Michel, Son, Elizaveta, Angelakakis, George, Rana, Navin, Hugais, Muna, Torrente, Mariana P

“…Amyotrophic lateral sclerosis (ALS) is an incurable neurodegenerative disease that often occurs concurrently with frontotemporal dementia (FTD), another…”
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Neurodegenerative Disease Proteinopathies Are Connected to Distinct Histone Post-translational Modification Landscapes by Chen, Karen, Bennett, Seth A, Rana, Navin, Yousuf, Huda, Said, Mohamed, Taaseen, Sadiqa, Mendo, Natalie, Meltser, Steven M, Torrente, Mariana P

“…Amyotrophic lateral sclerosis (ALS) and Parkinson’s disease (PD) are devastating neurodegenerative diseases involving the progressive degeneration of neurons…”
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Impaired RNA Binding Does Not Prevent Histone Modification Changes in a FUS ALS/FTD Yeast Model by Bennett, Seth A, Cobos, Samantha N, Son, Elizaveta, Segal, Rianna, Mathew, Shana, Yousuf, Huda, Torrente, Mariana P

“…Mutations in the RNA-binding protein FUS are linked to amyotrophic lateral sclerosis and frontotemporal dementia (ALS/FTD). FUS mutants mislocalize and…”
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Characterizing Histone Post-translational Modification Alterations in Yeast Neurodegenerative Proteinopathy Models by Bennett, Seth A, Cobos, Samantha N, Meykler, Marcella, Fallah, Michel, Rana, Navin, Chen, Karen, Torrente, Mariana P

“…Neurodegenerative diseases, such as amyotrophic lateral sclerosis (ALS) and Parkinson's disease (PD), cause the loss of hundreds of thousands of lives each…”
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Changes in Histone H3 Acetylation on Lysine 9 Accompany Aβ 1-40 Overexpression in an Alzheimer's Disease Yeast Model by Hugais, Muna M, Cobos, Samantha N, Bennett, Seth A, Paredes, Jailene, an, Genevieve, Torrente, Mariana P

“…Alzheimer’s Disease (AD), the most common type of dementia, is a neurodegenerative disease characterized by plaques of amyloid-beta (Aβ) peptides found in the…”
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