Search Results - "Bennett, LM"

A Strong Candidate for the Breast and Ovarian Cancer Susceptibility Gene BRCA1 by Miki, Yoshio, Swensen, Jeff, Shattuck-Eidens, Donna, Futreal, P. Andrew, Harshman, Keith, Tavtigian, Sean, Liu, Qingyun, Cochran, Charles, Bennett, L. Michelle, Ding, Wei, Bell, Russell, Rosenthal, Judith, Hussey, Charles, Tran, Thanh, McClure, Melody, Frye, Cheryl, Hattier, Tom, Phelps, Robert, Haugen-Strano, Astrid, Katcher, Harold, Yakumo, Kazuko, Gholami, Zahra, Shaffer, Daniel, Stone, Steven, Bayer, Steven, Wray, Christian, Bogden, Robert, Dayananth, Priya, Ward, John, Tonin, Patricia, Narod, Steven, Bristow, Pam K., Norris, Frank H., Helvering, Leah, Morrison, Paul, Rosteck, Paul, Lai, Mei, Barrett, J. Carl, Lewis, Cathryn, Neuhausen, Susan, Cannon-Albright, Lisa, Goldgar, David, Wiseman, Roger, Kamb, Alexander, Skolnick, Mark H.

“…A strong candidate for the 17q-linked BRCA1 gene, which influences susceptibility to breast and ovarian cancer, has been identified by positional cloning…”
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BRCA1 Mutations in Primary Breast and Ovarian Carcinomas by Futreal, P. Andrew, Liu, Qingyun, Shattuck-Eidens, Donna, Cochran, Charles, Harshman, Keith, Tavtigian, Sean, Bennett, L. Michelle, Haugen-Strano, Astrid, Swensen, Jeff, Miki, Yoshio, Eddington, Ken, McClure, Melody, Frye, Cheryl, Weaver-Feldhaus, Jane, Ding, Wei, Gholami, Zahra, Söderkvist, Peter, Terry, Lori, Jhanwar, Suresh, Berchuck, Andrew, Iglehart, J. Dirk, Marks, Jeff, Ballinger, Dennis G., Barrett, J. Carl, Skolnick, Mark H., Kamb, Alexander, Wiseman, Roger

“…Loss of heterozygosity data from familial tumors suggest that BRCA1, a gene that confers susceptibility to ovarian and early-onset breast cancer, encodes a…”
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Cancer susceptibility of mice with a homozygous deletion in the COOH-terminal domain of the Brca2 gene by MCALLISTER, Kimberly A, BENNETT, L. Michelle, EDDY, E. Mitch, DAVIS, Barbara J, WISEMAN, Roger W, HOULE, Chris D, WARD, Toni, MALPHURS, Jason, COLLINS, N. Keith, CACHAFEIRO, Carol, HASEMAN, Joseph, GOULDING, Eugenia H, BUNCH, Donna

“…Inherited mutations of the human BRCA2 gene confer increased risks for developing breast, ovarian, and several other cancers. Unlike previously described Brca2…”
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Impact of environmental exposures on the mutagenicity/carcinogenicity of heterocyclic amines by Felton, James S., Knize, Mark G., Bennett, L.Michelle, Malfatti, Michael A., Colvin, Michael E., Kulp, Kristen S.

“…Carcinogenic heterocyclic amines are produced from overcooked foods and are highly mutagenic in most short-term test systems. One of the most abundant of these…”
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A Potent Modifier of Liver Cancer Risk on Distal Mouse Chromosome 1: Linkage Analysis and Characterization of Congenic Lines by Bilger, Andrea, Bennett, L. Michelle, Carabeo, Reynaldo A, Chiaverotti, Teresa A, Dvorak, Cecily, Liss, Kristin M, Schadewald, Susan A, Pitot, Henry C, Drinkwater, Norman R

“…The C3H/HeJ (C3H) and CBA/J (CBA) mouse strains are classical mouse models of cancer susceptibility, exhibiting high risks for both spontaneous and chemically…”
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PhIP Carcinogenicity in Breast Cancer:  Computational and Experimental Evidence for Competitive Interactions with Human Estrogen Receptor by Bennion, Brian J, Cosman, Monique, Lightstone, Felice C, Knize, Mark G, Montgomery, Jennifer L, Bennett, L. Michelle, Felton, James S, Kulp, Kristen S

“…Many carcinogens have been shown to cause tissue specific tumors in animal models. The mechanism for this specificity has not been fully elucidated and is…”
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A targeted mouse Brca1 mutation removing the last BRCT repeat results in apoptosis and embryonic lethality at the headfold stage by Hohenstein, P, Kielman, M F, Breukel, C, Bennett, L M, Wiseman, R, Krimpenfort, P, Cornelisse, C, van Ommen, G J, Devilee, P, Fodde, R

“…A mouse model with a targeted mutation in the 3' end of the endogenous Brca1 gene, Brca1(1700T), was generated to compare the phenotypic consequences of…”
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Hammett 13C NMR and X-ray studies of π-allylpalladium phosphinooxazoline chiral ligand complexes by Armstrong, Paul B., Bennett, Lisa M., Constantine, Ryan N., Fields, Jessica L., Jasinski, Jerry P., Staples, Richard J., Bunt, Richard C.

“…[Display omitted] The transmission of substituent effects across the palladium center to the allyl carbons is monitored by 13C NMR and X-ray crystallography as…”
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Identification of mammary carcinogens in rodent bioassays by Bennett, L. Michelle, Davis, Barbara J.

“…Results from chemical carcinogenesis studies in rodents are useful to identify substances in our environment that may contribute to cancer development. The…”
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Breast cancer: Genetic predisposition and exposure to radiation by Bennett, L. Michelle

“…The identification of breast cancer susceptibility genes, such as BRCA1, BRCA2, ATM, and p53, has been accompanied by the examination of the effects of…”
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Brca1 and Brca2 expression patterns in mitotic and meiotic cells of mice by Blackshear, P E, Goldsworthy, S M, Foley, J F, McAllister, K A, Bennett, L M, Collins, N K, Bunch, D O, Brown, P, Wiseman, R W, Davis, B J

“…The mouse homologues of the breast cancer susceptibility genes, Brca1 and Brca2, are expressed in a cell cycle-dependent fashion in vitro and appear to be…”
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Flor-Essence® herbal tonic does not inhibit mammary tumor development in Sprague Dawley rats by BENNETT, L. Michelle, MONTGOMERY, Jennifer L, STEINBERG, Seth M, KULP, Kristen S

“…Women who are diagnosed with breast cancer often self-administer complementary and alternative medicines to augment their conventional treatments, improve…”
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Mice heterozygous for a Brca1 or Brca2 mutation display distinct mammary gland and ovarian phenotypes in response to diethylstilbestrol by BENNETT, L. M, MCALLISTER, K. A, MALPHURS, J, WARD, T, COLLINS, N. K, SEELY, J. C, GOWEN, L. C, KOLLER, B. H, DAVIS, B. J, WISEMAN, R. W

“…Women who inherit mutations in the breast cancer susceptibility genes, BRCA1 and BRCA2, are predisposed to the development of breast and ovarian cancer. We…”
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Identification of Hepatocarcinogen-Resistance Genes in DBA/2 Mice by Lee, G. H, Bennett, L. M, Carabeo, R. A, Drinkwater, N. R

“…Male DBA/2J mice are approximately 20-fold more susceptible than male C57BL/6J mice to hepatocarcinogenesis induced by perinatal treatment with…”
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The partnership between breast cancer advocates and scientists by Platner, Janice H., Bennett, L. Michelle, Millikan, Robert, Barker, Mary D.G.

“…The National Breast Cancer Coalition (NBCC) is a grassroots organization that represents breast cancer advocates and is committed to eradicating breast cancer…”
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Characterization of the rat and mouse homologues of the BRCA2 breast cancer susceptibility gene by MCALLISTER, K. A, HAUGEN-STRANO, A, HAGEVIK, S, BROWNLEE, H. A, COLLINS, N. K, FUTREAL, P. A, BENNETT, L. M, WISEMAN, R. W

“…Inherited BRCA2 mutations confer profound susceptibility to human breast and ovarian cancer. The rat and mouse Brca2 homologues share 58% and 59% identity (72%…”
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Brca1 is expressed independently of hormonal stimulation in the mouse ovary by Phillips, K W, Goldsworthy, S M, Bennett, L M, Brownlee, H A, Wiseman, R W, Davis, B J

“…BRCA1 mutations lead to cancer susceptibility in hormonally dependent tissues such as the ovary and breast. To test the hypothesis that Brca1 expression in the…”
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Sequence analysis of the rat Brca1 homolog and its promoter region by Bennett, L M, Brownlee, H A, Hagavik, S, Wiseman, R W

“…Since the identification of the human breast and ovarian cancer gene, BRCA1, a large spectrum of germline mutations has been characterized that predispose…”
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Brca2-Null Embryonic Survival is Prolonged on the BALB/c Genetic Background by Bennett, L. Michelle, McAllister, Kimberly A., Blackshear, Pamela E., Malphurs, Jason, Goulding, Gina, Collins, N. Keith, Ward, Toni, Bunch, Donna O., Eddy, Edward M., Davis, Barbara J., Wiseman, Roger W.

“…Women who inherit mutations in the BRCA2 cancer susceptibility gene have an 85% chance of developing breast cancer. The function of the BRCA2 gene remains…”
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Isolation of a diverged homeobox gene, MOX1, from the BRCA1 region on 17q21 by solution hybrid capture by Futreal, P A, Cochran, C, Rosenthal, J, Miki, Y, Swenson, J, Hobbs, M, Bennett, L M, Haugen-Strano, A, Marks, J, Barrett, J C

“…Using the technique of solution hybridization coupled with magnetic bead capture, we have isolated a novel homeobox-containing gene from the BRCA1 region of…”
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