Search Results - "Bennett, Holly A."

Functional Discovery via a Compendium of Expression Profiles by Hughes, Timothy R, Marton, Matthew J, Jones, Allan R, Roberts, Christopher J, Stoughton, Roland, Armour, Christopher D, Bennett, Holly A, Coffey, Ernest, Dai, Hongyue, He, Yudong D, Kidd, Matthew J, King, Amy M, Meyer, Michael R, Slade, David, Lum, Pek Y, Stepaniants, Sergey B, Shoemaker, Daniel D, Gachotte, Daniel, Chakraburtty, Kalpana, Simon, Julian, Bard, Martin, Friend, Stephen H

“…Ascertaining the impact of uncharacterized perturbations on the cell is a fundamental problem in biology. Here, we describe how a single assay can be used to…”
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Signaling and Circuitry of Multiple MAPK Pathways Revealed by a Matrix of Global Gene Expression Profiles by Roberts, Christopher J., Nelson, Bryce, Marton, Matthew J., Stoughton, Roland, Meyer, Michael R., Bennett, Holly A., He, Yudong D., Dai, Hongyue, Walker, Wynn L., Hughes, Timothy R., Tyers, Mike, Boone, Charles, Friend, Stephen H.

“…Genome-wide transcript profiling was used to monitor signal transduction during yeast pheromone response. Genetic manipulations allowed analysis of changes in…”
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Drug target validation and identification of secondary drug target effects using DNA microarrays by Marton, Matthew J., DeRisi, Joseph L., Bennett, Holly A., Iyer, Vishwanath R., Meyer, Michael R., Roberts, Christopher J., Stoughton, Roland, Burchard, Julja, Slade, David, Dai, Hongyue, Bassett, Douglas E., Hartwell, Leland H., Brown, Patrick O., Friend, Stephen H.

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Drug target validation and identification of secondary drug target effects using DNA microarrays by Friend, Stephen H, Marton, Matthew J, DeRisi, Joseph L, Bennett, Holly A, Iyer, Vishwanath R, Meyer, Michael R, Roberts, Christopher J, Stoughton, Roland, Burchard, Julja, Slade, David, Dai, Hongyue, Bassett, Douglas E, Hartwell, Leland H, Brown, Patrick O

“…We describe here a method for drug target validation and identification of secondary drug target effects based on genome-wide gene expression patterns. The…”
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