Search Results - "Bennett, F."

Immune cell regulation of glia during CNS injury and disease by Greenhalgh, Andrew D., David, Sam, Bennett, F. Chris

“…Glial cells are abundant in the CNS and are essential for brain development and homeostasis. These cells also regulate tissue recovery after injury and their…”
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The influence of environment and origin on brain resident macrophages and implications for therapy by Bennett, Mariko L., Bennett, F. Chris

“…Microglia are the tissue-resident macrophages of the brain and spinal cord. They are critical players in the development, normal function, and decline of the…”
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A Combination of Ontogeny and CNS Environment Establishes Microglial Identity by Bennett, F. Chris, Bennett, Mariko L., Yaqoob, Fazeela, Mulinyawe, Sara B., Grant, Gerald A., Hayden Gephart, Melanie, Plowey, Edward D., Barres, Ben A.

“…Microglia, the brain’s resident macrophages, are dynamic CNS custodians with surprising origins in the extra-embryonic yolk sac. The consequences of their…”
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The immune system and psychiatric disease: a basic science perspective by Bennett, F. C., Molofsky, A. V.

“…Summary Mental illness exerts a major burden on human health, yet evidence‐based treatments are rudimentary due to a limited understanding of the underlying…”
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Diverse Requirements for Microglial Survival, Specification, and Function Revealed by Defined-Medium Cultures by Bohlen, Christopher J., Bennett, F. Chris, Tucker, Andrew F., Collins, Hannah Y., Mulinyawe, Sara B., Barres, Ben A.

“…Microglia, the resident macrophages of the CNS, engage in various CNS-specific functions that are critical for development and health. To better study…”
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Molecular and metabolic heterogeneity of astrocytes and microglia by Hasel, Philip, Aisenberg, William H., Bennett, F. Chris, Liddelow, Shane A.

“…Astrocytes and microglia are central players in a myriad of processes in the healthy and diseased brain, ranging from metabolism to immunity. The crosstalk…”
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New tools for studying microglia in the mouse and human CNS by Bennett, Mariko L., Bennett, F. Chris, Liddelow, Shane A., Ajami, Bahareh, Zamanian, Jennifer L., Fernhoff, Nathaniel B., Mulinyawe, Sara B., Bohlen, Christopher J., Adil, Aykezar, Tucker, Andrew, Weissman, Irving L., Chang, Edward F., Li, Gordon, Grant, Gerald A., Gephart, Melanie G. Hayden, Barres, Ben A.

“…The specific function of microglia, the tissue resident macrophages of the brain and spinal cord, has been difficult to ascertain because of a lack of tools to…”
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Prospective Trial of a Pediatric Ventricular Assist Device by Fraser, Charles D, Jaquiss, Robert D.B, Rosenthal, David N, Humpl, Tilman, Canter, Charles E, Blackstone, Eugene H, Naftel, David C, Ichord, Rebecca N, Bomgaars, Lisa, Tweddell, James S, Massicotte, M. Patricia, Turrentine, Mark W, Cohen, Gordon A, Devaney, Eric J, Pearce, F. Bennett, Carberry, Kathleen E, Kroslowitz, Robert, Almond, Christopher S

“…In a single-group trial, 48 children with severe heart failure received a ventricular assist device designed for children. Survival rates were significantly…”
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Identifying wildlife corridors for the restoration of regional habitat connectivity: A multispecies approach and comparison of resistance surfaces by Liu, Canran, Newell, Graeme, White, Matt, Bennett, Andrew F

“…Many large-scale connectivity initiatives have been proposed around the world with the aim of maintaining or restoring connectivity to offset the impacts on…”
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Microglia cannibalism during neurodevelopment results in necroptotic cell death by Bennett, F Chris, Bennett, Mariko L

“…Clearance of dying neurons by microglia is critical to healthy neurodevelopment, but what else do microglia eat? A new study in PLOS Biology demonstrates that…”
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Atomistic Simulations of Pore Formation and Closure in Lipid Bilayers by Bennett, W. F. Drew, Sapay, Nicolas, Tieleman, D. Peter

“…Cellular membranes separate distinct aqueous compartments, but can be breached by transient hydrophilic pores. A large energetic cost prevents pore formation,…”
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Accelerators for Classical Molecular Dynamics Simulations of Biomolecules by Jones, Derek, Allen, Jonathan E., Yang, Yue, Drew Bennett, William F., Gokhale, Maya, Moshiri, Niema, Rosing, Tajana S.

“…Atomistic Molecular Dynamics (MD) simulations provide researchers the ability to model biomolecular structures such as proteins and their interactions with…”
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The Molecular Diversity of Adaptive Convergence by Tenaillon, Olivier, Rodríguez-Verdugo, Alejandra, Gaut, Rebecca L., McDonald, Pamela, Bennett, Albert F., Long, Anthony D., Gaut, Brandon S.

“…To estimate the number and diversity of beneficial mutations, we experimentally evolved 115 populations of Escherichia coli to 42.2°C for 2000 generations and…”
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Defective NADPH production in mitochondrial disease complex I causes inflammation and cell death by Balsa, Eduardo, Perry, Elizabeth A., Bennett, Christopher F., Jedrychowski, Mark, Gygi, Steven P., Doench, John G., Puigserver, Pere

“…Electron transport chain (ETC) defects occurring from mitochondrial disease mutations compromise ATP synthesis and render cells vulnerable to nutrient and…”
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Distribution of Amino Acids in a Lipid Bilayer from Computer Simulations by MacCallum, Justin L., Bennett, W. F. Drew, Tieleman, D. Peter

“…We have calculated the distribution in a lipid bilayer of small molecules mimicking 17 natural amino acids in atomistic detail by molecular dynamics…”
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Isolation and Culture of Microglia by Bohlen, Christopher J, Bennett, F Chris, Bennett, Mariko L

“…Microglia represent 5-10% of cells in the central nervous system and contribute to the development, homeostasis, injury, and repair of neural tissues. As the…”
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Engineering an inhibitor-resistant human CSF1R variant for microglia replacement by Chadarevian, Jean Paul, Lombroso, Sonia I, Peet, Graham C, Hasselmann, Jonathan, Tu, Christina, Marzan, Dave E, Capocchi, Joia, Purnell, Freddy S, Nemec, Kelsey M, Lahian, Alina, Escobar, Adrian, England, Whitney, Chaluvadi, Sai, O'Brien, Carleigh A, Yaqoob, Fazeela, Aisenberg, William H, Porras-Paniagua, Matias, Bennett, Mariko L, Davtyan, Hayk, Spitale, Robert C, Blurton-Jones, Mathew, Bennett, F Chris

“…Hematopoietic stem cell transplantation (HSCT) can replace endogenous microglia with circulation-derived macrophages but has high mortality. To mitigate the…”
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Argonaute2 complexes carry a population of circulating microRNAs independent of vesicles in human plasma by Arroyo, Jason D, Chevillet, John R, Kroh, Evan M, Ruf, Ingrid K, Pritchard, Colin C, Gibson, Donald F, Mitchell, Patrick S, Bennett, Christopher F, Pogosova-Agadjanyan, Era L, Stirewalt, Derek L, Tait, Jonathan F, Tewari, Muneesh

“…MicroRNAs (miRNAs) circulate in the bloodstream in a highly stable, extracellular form and are being developed as blood-based biomarkers for cancer and other…”
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Fat Cadherin Modulates Organ Size in Drosophila via the Salvador/Warts/Hippo Signaling Pathway by Bennett, F. Christian, Harvey, Kieran F.

“…The atypical Fat cadherin has long been known to control cell proliferation and organ size in Drosophila, but the mechanism by which Fat controls these…”
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Glia in neurodegeneration by Bennett, F. Chris, Sloan, Steven A.

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