Search Results - "Benlimame, N."
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Regulation of focal adhesion turnover by ErbB signalling in invasive breast cancer cells
Published in British journal of cancer (24-02-2009)“…A crucial early event by which cancer cells switch from localised to invasive phenotype is initiated by the acquisition of autonomous motile properties; a…”
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Clathrin-mediated endocytosis and recycling of autocrine motility factor receptor to fibronectin fibrils is a limiting factor for NIH-3T3 cell motility
Published in Journal of cell science (01-09-2000)“…Autocrine motility factor receptor (AMF-R) is internalized via a clathrin-independent pathway to smooth endoplasmic reticulum tubules. This endocytic pathway…”
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Autocrine Motility Factor Receptor Is a Marker for a Distinct Membranous Tubular Organelle
Published in The Journal of cell biology (01-04-1995)“…Autocrine motility factor (AMF) is secreted by tumor cells and is capable of stimulating the motility of the secreting cells. In addition to being expressed on…”
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A novel parasite-derived suicide gene for cancer gene therapy with specificity for lung cancer cells
Published in Human gene therapy (01-09-2001)“…The enzyme hypoxanthine-guanine phosphoribosyltransferase (HGPRT) expressed by the parasite Trypanosoma brucei (Tb) can convert allopurinol, a purine analogue,…”
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FAK signaling is critical for ErbB-2/ErbB-3 receptor cooperation for oncogenic transformation and invasion
Published in The Journal of cell biology (07-11-2005)“…The overexpression of members of the ErbB tyrosine kinase receptor family has been associated with cancer progression. We demonstrate that focal adhesion…”
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E6 E7 proteins of HPV type 16 and ErbB-2 cooperate to induce neoplastic transformation of primary normal oral epithelial cells
Published in Oncogene (15-01-2004)“…Head and neck squamous cell carcinomas (HNSCC) are characterized by a marked propensity for local invasion and spread to cervical lymph nodes, with distant…”
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Differential regulation of tumor angiogenesis by distinct ErbB homo- and heterodimers
Published in Molecular biology of the cell (01-11-2002)“…Interactions between cancer cells and their microenvironment are critical for the development and progression of solid tumors. This study is the first to…”
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Technology & tools development
Published in Annals of oncology (01-06-2012)Get full text
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Localization of autocrine motility factor receptor to caveolae and clathrin-independent internalization of its ligand to smooth endoplasmic reticulum
Published in Molecular biology of the cell (01-07-1998)“…Autocrine motility factor receptor (AMF-R) is a cell surface receptor that is also localized to a smooth subdomain of the endoplasmic reticulum, the AMF-R…”
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Regulation of multiple tumor microenvironment markers by overexpression of single or paired combinations of ErbB receptors
Published in Cancer research (Chicago, Ill.) (01-07-2003)“…The progression of primary tumors to an invasive phenotype requires dynamic changes in multiple cellular and local tumor microenvironment markers. In this…”
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Transcriptional Regulation of the TFIIH Transcription Repair Components XPB and XPD by the Hepatitis B Virus x Protein in Liver Cells and Transgenic Liver Tissue
Published in The Journal of biological chemistry (27-04-2001)“…Human hepatitis B virus is a risk factor for the development of hepatocellular carcinoma. The hepatitis B virus x protein (HBx) has been shown to inactivate…”
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Regulation of E-cadherin/catenin complex patterns by epidermal growth factor receptor modulation in human lung cancer cells
Published in Lung cancer (Amsterdam, Netherlands) (01-07-2002)“…We previously demonstrated that a ligand-blocking monoclonal antibody (mAb) against the epidermal growth factor-receptor (EGF-R), LA1, induced morphological…”
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145 A mitogenic-independent mechanism for ErbB receptor-induced tumour cell invasion
Published in European journal of cancer supplements (01-09-2004)Get full text
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RBT1, a novel transcriptional co-activator, binds the second subunit of replication protein A
Published in Nucleic acids research (15-09-2000)“…Replication Protein A (RPA) is required for DNA recombination, repair and replication in all eukaryotes. RPA participation in these pathways is mediated by…”
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Identification of the interferon-inducible double-stranded RNA-dependent protein kinase as a regulator of cellular response to bulky adducts
Published in Cancer research (Chicago, Ill.) (15-12-2000)“…The double-stranded RNA-dependent protein kinase PKR plays a central role in IFN-mediated antiviral response. The ability of PKR mutants to transform rodent…”
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The AMF-R tubule is a smooth ilimaquinone-sensitive subdomain of the endoplasmic reticulum
Published in Journal of cell science (01-12-1997)“…Autocrine motility factor receptor (AMF-R) is a marker for a distinct smooth membranous tubule. Ilimaquinone (IQ) is a sea sponge metabolite which induces the…”
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Action of low calcemic 1alpha,25-dihydroxyvitamin D3 analogue EB1089 in head and neck squamous cell carcinoma
Published in JNCI : Journal of the National Cancer Institute (16-05-2001)“…1alpha,25-Dihydroxyvitamin D(3) [1,25(OH)(2)D(3)] and its analogues inhibit growth of various types of cancer cells. Although the therapeutic potential of…”
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