Search Results - "Benlasfer, Ouidad"

Mesenchymal stromal cells of myelodysplastic syndrome and acute myeloid leukemia patients have distinct genetic abnormalities compared with leukemic blasts by Blau, Olga, Baldus, Claudia Dorothea, Hofmann, Wolf-Karsten, Thiel, Gundula, Nolte, Florian, Burmeister, Thomas, Türkmen, Seval, Benlasfer, Ouidad, Schümann, Elke, Sindram, Annette, Molkentin, Mara, Mundlos, Stefan, Keilholz, Ulrich, Thiel, Eckhard, Blau, Igor Wolfgang

“…Mesenchymal stromal cells (MSCs) are an essential cell type of the hematopoietic microenvironment. Concerns have been raised about the possibility that MSCs…”
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Early Thymic Progenitor Leukemia (ETP-ALL) in Adults: A Distinct Molecular Entity by Neumann, Martin, Heesch, Sandra, Seide, Claudia, Benlasfer, Ouidad, Burmeister, Thomas, Schwartz, Stefan, Gökbuget, Nicola, Hoelzer, Dieter, Hofmann, Wolf-Karsten, Thiel, Eckhard, Baldus, Claudia D

“…Abstract 3551 Early thymic progenitor acute lymphoblastic leukemia (ETP-ALL) has been characterized as new T-ALL subgroup characterized by a specific gene…”
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High WT1 Expression Is Associated with a Shorter Time to Complete Remission After ATRA Based Induction Therapy In Acute Promyelocytic Leukemia by Nolte, Florian, Nowak, Daniel, Hecht, Anna, Erben, Philipp, Hanfstein, Benjamin, Benlasfer, Ouidad, Buchner, Thomas, Hofmann, Wolf-Karsten, Lengfelder, Eva

“…Abstract 1694 In acute promyelocytic leukemia (APL) the t(15;17) is detectable in the vast majority of cases and leads to the fusion transcript PML-RARα. The…”
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Antileukemic Activity of the HSP70 Inhibitor Pifithrin-μ by Kaiser, Martin, Kuehnl, Andrea, Ortiz-Tanchez, Jutta, Benlasfer, Ouidad, Schlee, Cornelia, Heesch, Sandra, Thiel, Eckhard, Baldus, Claudia

“…Abstract 3306 Heat shock protein (HSP) 70 is aberrantly expressed in acute leukemias and other hematologic and solid malignancies, promoting tumor cell…”
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Prediction of Response to Treatment with Lenalidomide in Patients with Non-Del 5q Myelodysplastic Syndrome by Gene Expression Profiling Remains Difficult by Hofmann, Wolf-Karsten, Nolte, Florian, Benlasfer, Ouidad, Thiel, Eckhard, Ehninger, Gerhard, Platzbecker, Uwe

“…Abstract 2781 Poster Board II-757 Lenalidomide belongs to a proprietary class of immunmodulatory drugs showing therapeutic activity in patients with…”
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Consequent Iron Chelation Therapy in Patients with Low Risk Myelodysplastic Syndrome Leads to up-Regulation of .CXCL12, JAK2 and HSF2: Possible Link Between Iron Chelation and Improvement of Erythropoiesis by Nolte, Florian, Neumann, Martin, Benlasfer, Ouidad, Heesch, Sandra, Thiel, Eckhard, Platzbecker, Uwe, Hofmann, Wolf-Karsten

“…Abstract 2787 Poster Board II-763 Myelodysplastic syndromes (MDS) are characterized by ineffective hematopoiesis and an increased risk of evolution to acute…”
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High Rate of FLT3 Mutations In Adult ETP-ALL by Neumann, Martin, Coskun, Ebru, Benlasfer, Ouidad, Heesch, Sandra, Schwartz, Stefan, Goekbuget, Nicola, Hoelzer, Dieter, Hofmann, Wolf-Karsten, Thiel, Eckhard, Baldus, Claudia

“…Abstract 1031 Mutations of FLT3 are recognized as important prognostic factor in acute myeloid leukemia (AML) with an impact on new therapeutic strategies…”
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Identification of Highly Clonal Cells in CD34+ and Unselected Bone Marrow Samples From Patients with Myelodysplastic Syndrome Using a Sensitive Quantitative PCR Approach by Mossner, Maximilian, Nowak, Daniel, Benlasfer, Ouidad, Reins, Jana, Hopfer, Olaf Joachim, Baldus, Claudia D, Thiel, Eckhard, Hofmann, Wolf-Karsten

“…Abstract 1760 Poster Board I-786 Myelodysplastic syndromes (MDS) are clonal hematologic malignancies with molecular defects most probably arising in the…”
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Mesenchimal Stroma Cells From Patients with Myelodysplastic Syndrome and Acute Myeloid Leukemia Show Distinct Cytogenetic and DNA-Mutation Data as Compared with Bone Marrow Leukemic Blasts by Blau, Olga, Hofmann, Wolf-Karsten, Baldus, Claudia D, Thiel, Gundula, Nolte, Florian, Schuemann, Elke, Benlasfer, Ouidad, Sindram, Annette, Thiel, Eckhard, Blau, Igor W.

“…Abstract 4697 Bone marrow mesenchymal stroma cells (BMSC) are key components of the hematopoietic microenvironment. BMSC from patients with acute myeloid…”
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Detection of Differential Mitotic Cell Ages in Bone Marrow CD34+ Cells Selected from Patients with Myelodysplastic Syndrome and Acute Leukemia by Pyrosequencing Analysis of An Epigenetic Molecular Clock DNA Signature by Mossner, Maximilian, Hopfer, Olaf, Baldus, Claudia D, Neumann, Uwe, Kmetsch, Anke, Benlasfer, Ouidad, Thiel, Eckhard, Hofmann, Wolf-Karsten

“…Introduction: Disturbed proliferation and differentiation are the most crucial oncogeneic factors leading to malignant turnover of hematopoiesis in myeloid…”
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Detection of differential mitotic cell age in bone marrow CD34+ cells from patients with myelodysplastic syndrome and acute leukemia by analysis of an epigenetic molecular clock DNA signature by Mossner, Maximilian, Hopfer, Olaf, Nowak, Daniel, Baldus, Claudia D, Neumann, Uwe, Kmetsch, Anke, Benlasfer, Ouidad, John, Thilo, Perka, Carsten, Thiel, Eckhard, Hofmann, Wolf-Karsten

“…Objective Recently, the “epigenetic molecular clock hypothesis” linked increasing DNA methylation in a distinct CpG island in the cardiac-specific homeobox…”
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Analysis of Chromosomal Aberrations and DNA Mutations in Bone Marrow Mesenchymal Stroma Cells from Patients with Myelodysplastic Syndrome Amd Acute Myeloid Leukemia by Blau, Olga, Hofmann, Wolf-Karsten, Blau, Igor W., Baldus, Claudia D, Nolte, Florian, Thiel, Gundula, Schuemann, Elke, Benlasfer, Ouidad, Thiel, Eckhard

“…Introduction: The biology of myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML) is not well understood. In MDS, ineffective hematopoiesis may…”
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