Search Results - "Benitez, Julio"
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Laser capture microscopy coupled with Smart-seq2 for precise spatial transcriptomic profiling
Published in Nature communications (08-07-2016)“…Laser capture microscopy (LCM) coupled with global transcriptome profiling could enable precise analyses of cell populations without the need for tissue…”
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Evaluation of cellular uptake, cytotoxicity and cellular ultrastructural effects of heteroleptic oxidovanadium(IV) complexes of salicylaldimines and polypyridyl ligands
Published in Journal of inorganic biochemistry (01-01-2017)“…Searching for prospective vanadium-based drugs for cancer treatment, a new series of structurally related [VIVO(L−2H)(NN)] compounds (1–8) was developed. They…”
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Preventable risk factors for type 2 diabetes can be detected using noninvasive spontaneous electroretinogram signals
Published in PloS one (12-01-2023)“…Given the ever-increasing prevalence of type 2 diabetes and obesity, the pressure on global healthcare is expected to be colossal, especially in terms of…”
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Leaning Tower of Pisa? Avoiding a major neurologic complication with the erector spinae plane block
Published in Regional anesthesia and pain medicine (01-07-2019)“…According to Panjabi et al 4, sustained muscle hypertonicity is often observed with spinal instability, and this may be an adaptive response of the body to…”
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Vanadium polypyridyl compounds as potential antiparasitic and antitumoral agents: New achievements
Published in Journal of inorganic biochemistry (01-02-2011)“…In the search for new therapeutic tools against diseases produced by kinetoplastid parasites five vanadyl complexes, [VIVO(L-2H)(phen)], including…”
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6
Characterization of the consistent completion of analytic hierarchy process comparison matrices using graph theory
Published in Journal of multi-criteria decision analysis (01-01-2019)“…Decision‐making is frequently affected by uncertainty and/or incomplete information, which turn decision‐making into a complex task. It is often the case that…”
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LCM-Seq: A Method for Spatial Transcriptomic Profiling Using Laser Capture Microdissection Coupled with PolyA-Based RNA Sequencing
Published in Methods in molecular biology (Clifton, N.J.) (2018)“…LCM-seq couples laser capture microdissection of cells from frozen tissues with polyA-based RNA sequencing and is applicable to single neurons. The method…”
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New oxidovanadium(IV) N-acylhydrazone complexes: promising antileishmanial and antitrypanosomal agents
Published in European journal of medicinal chemistry (01-04-2013)“…Searching for new promising metal-based hits against Trypanosoma cruzi and Leishmania parasites, two related oxidovanadium(IV) N-acylhydrazone complexes,…”
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Oxidovanadium(IV) and dioxidovanadium(V) complexes of tridentate salicylaldehyde semicarbazones: Searching for prospective antitrypanosomal agents
Published in Journal of inorganic biochemistry (01-10-2013)“…As a contribution to the identification of the relevant species for biological activity and the understanding of structure–activity relationships of…”
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A short proof of a matrix decomposition with applications
Published in Linear algebra and its applications (01-02-2013)“…We give a very short proof of the main result of J. Benı´tez, A new decomposition for square matrices, Electron. J. Linear Algebra 20 (2010) 207–225. Also, we…”
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Impact of genetic polymorphisms on tacrolimus pharmacokinetics and the clinical outcome of renal transplantation
Published in Transplant international (01-04-2012)“…We retrospectively examined the association of polymorphisms in the CYP3A, CYP2J2, CYP2C8, and ABCB1 genes with pharmacokinetic (PKs) and pharmacodynamic (PDs)…”
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Expanding the family of heteroleptic oxidovanadium(IV) compounds with salicylaldehyde semicarbazones and polypyridyl ligands showing anti-Trypanosoma cruzi activity
Published in Journal of inorganic biochemistry (01-06-2015)“…Searching for prospective vanadium-based drugs for the treatment of Chagas disease, a new series of heteroleptic [VIVO(L-2H)(NN)] compounds was developed by…”
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13
Design of vanadium mixed-ligand complexes as potential anti-protozoa agents
Published in Journal of inorganic biochemistry (01-04-2009)“…In the search for new therapeutic tools against Chagas’ disease (American Trypanosomiasis) four novel mixed-ligand vanadyl complexes, [V IVO(L 2-2H)(L 1)],…”
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A novel vanadyl complex with a polypyridyl DNA intercalator as ligand: A potential anti-protozoa and anti-tumor agent
Published in Journal of inorganic biochemistry (01-10-2009)“…In the search for new metal-based drugs for the treatment of tumoral and parasitic diseases a vanadyl complex, [V IVO(SO 4)(H 2O) 2(dppz)]·2H 2O, that includes…”
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Chromosomal instability in a patient with ring chromosome 14 syndrome: a case report
Published in Molecular cytogenetics (18-07-2024)“…Ring chromosome 14 syndrome is a rare disorder primarily marked by early-onset epilepsy, microcephaly, distinctive craniofacial features, hypotonia,…”
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Exploring Oxidovanadium(IV) Complexes as YopH Inhibitors: Mechanism of Action and Modeling Studies
Published in ACS medicinal chemistry letters (08-10-2015)“…YopH tyrosine phosphatase, a virulence factor produced by pathogenic species of Yersinia, is an attractive drug target. In this work, three oxidovanadium(IV)…”
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Differential neuronal vulnerability identifies IGF-2 as a protective factor in ALS
Published in Scientific reports (16-05-2016)“…The fatal disease amyotrophic lateral sclerosis (ALS) is characterized by the loss of somatic motor neurons leading to muscle wasting and paralysis. However,…”
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Challenges in acute care surgery: penetrating vertebral artery injury in ‘extremis’ patient
Published in Trauma surgery & acute care open (05-04-2021)“…Given a suspected VA injury in zone 2 in a patient in critical hemodynamic state, and not having immediate angioembolization, we decided to maintain temporary…”
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Cytogenomic characterization of a de novo 4q34.1 deletion in a girl with mild dysmorphic features and a coagulation disorder
Published in Molecular cytogenetics (04-09-2021)“…Background 4q deletion syndrome is a rare chromosomal disorder that mostly arises de novo. The syndrome is characterized by craniofacial dysmorphism, digital…”
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Characterization of Consistent Completion of Reciprocal Comparison Matrices
Published in Abstract and Applied Analysis (01-01-2014)“…Analytic hierarchy process (AHP) is a leading multi-attribute decision-aiding model that is designed to help make better choices when faced with complex…”
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