Search Results - "Benitez, Itziar Ibarlucea"
-
1
Control of directed cell migration in vivo by membrane-to-cortex attachment
Published in PLoS biology (01-11-2010)“…Cell shape and motility are primarily controlled by cellular mechanics. The attachment of the plasma membrane to the underlying actomyosin cortex has been…”
Get full text
Journal Article -
2
Kinesins relocalize the chromosomal passenger complex to the midzone for spindle disassembly
Published in The Journal of cell biology (07-05-2018)“…Mitotic spindle disassembly after chromosome separation is as important as spindle assembly, yet the molecular mechanisms for spindle disassembly are unclear…”
Get full text
Journal Article -
3
Targeting myeloid suppressive cells revives cytotoxic anti-tumor responses in pancreatic cancer
Published in iScience (18-11-2022)“…Immunotherapy for cancer that aims to promote T cell anti-tumor activity has changed current clinical practice, where some previously lethal cancers have now…”
Get full text
Journal Article -
4
1187 Antibody-lectin bispecifics for glyco-immune checkpoint blockade
Published in Journal for immunotherapy of cancer (01-11-2023)“…BackgroundDespite the curative potential of checkpoint blockade immunotherapy, a majority of patients remain unresponsive to existing treatments. Glyco-immune…”
Get full text
Journal Article -
5
Siglecs-7/9 function as inhibitory immune checkpoints in vivo and can be targeted to enhance therapeutic antitumor immunity
Published in Proceedings of the National Academy of Sciences - PNAS (29-06-2021)“…Given the role of myeloid cells in T cell activation and in the antitumor response, targeting checkpoint molecules expressed on this population represents a…”
Get full text
Journal Article -
6
Targeting a scavenger receptor on tumor-associated macrophages activates tumor cell killing by natural killer cells
Published in Proceedings of the National Academy of Sciences - PNAS (15-12-2020)“…Tumor-associated macrophages (TAMs) can have protumor properties, including suppressing immune responses, promoting vascularization and, consequently,…”
Get full text
Journal Article -
7
A genomic toolkit to investigate kinesin and myosin motor function in cells
Published in Nature cell biology (01-03-2013)“…Coordination of multiple kinesin and myosin motors is required for intracellular transport, cell motility and mitosis. However, comprehensive resources that…”
Get full text
Journal Article -
8
Mechanisms of Mitotic Spindle Function in Saccharomyces cerevisiae
Published 01-01-2017“…Cell division is an essential process for multicellular organisms. The fundamental goal of mitosis is to duplicate and segregate the genetic material of one…”
Get full text
Dissertation -
9
Control of Directed Cell Migration In Vivo by Membrane-to-Cortex Attachment: e1000544
Published in PLoS biology (01-11-2010)“…Cell shape and motility are primarily controlled by cellular mechanics. The attachment of the plasma membrane to the underlying actomyosin cortex has been…”
Get full text
Journal Article