Search Results - "Benike, C J"

Idiotype Vaccination Using Dendritic Cells After Autologous Peripheral Blood Stem Cell Transplantation for Multiple Myeloma—A Feasibility Study by Reichardt, Volker L., Okada, Craig Y., Liso, Arcangelo, Benike, Claudia J., Stockerl-Goldstein, Keith E., Engleman, Edgar G., Blume, Karl G., Levy, Ronald

“…The idiotype (Id) determinant on the multiple myeloma (MM) protein can be regarded as a tumor-specific marker. Immunotherapy directed at the MM Id may stem the…”
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Evidence that T cell activation is required for HIV-1 entry in CD4+ lymphocytes by Gowda, SD, Stein, BS, Mohagheghpour, N, Benike, CJ, Engleman, EG

“…The relationship of T cell activation to HIV entry and generation of viral DNA intermediates was studied in freshly isolated CD4+ T lymphocytes. Unstimulated…”
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Recombinant interleukin 2 enhanced natural killer cell-mediated cytotoxicity in human lymphocyte subpopulations expressing the Leu 7 and Leu 11 antigens by Lanier, LL, Benike, CJ, Phillips, JH, Engleman, EG

“…Highly purified recombinant human interleukin 2 (rIL 2) markedly augments the natural killer (NK) cell-mediated cytotoxicity of peripheral blood lymphocytes…”
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Studies of a Human T Lymphocyte Antigen Recognized by a Monoclonal Antibody by Engleman, E. G., Warnke, R., Fox, R. I., Dilley, J., Benike, C. J., Levy, R.

“…A monoclonal antibody (designated L17F12) detects an antigen present on 95-100% of human peripheral T lymphocytes, the majority of thymocytes, and acute…”
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Activation of human T lymphocyte subsets: helper and suppressor/cytotoxic T cells recognize and respond to distinct histocompatibility antigens by Engleman, EG, Benike, CJ, Grumet, FC, Evans, RL

“…This study was directed at determining the major histocompatibility complex (MHC) antigens recognized by helper (Leu-3) and suppressor-cytotoxic (Leu-2) T…”
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Isolation and Utilization of Human Dendritic Cells from Peripheral Blood to Assay an In Vitro Primary Immune Response to Varicella-Zoster Virus Peptides by Jenkins, Darlene E., Yasukawa, Linda L., Benike, Claudia J., Engleman, Edgar G., Arvin, Ann M.

“…A human dendritic cell-based assay used to monitor a T cell proliferation response to viral peptides in vitro is described. Dendritic cells and autologous CD4+…”
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CTL Response to Mycobacterium tuberculosis: Identification of an Immunogenic Epitope in the 19-kDa Lipoprotein by Mohagheghpour, Nahid, Gammon, Dawn, Kawamura, Loyce Masae, van Vollenhoven, Annika, Benike, Claudia J, Engleman, Edgar G

“…The successful resolution of infection with Mycobacterium tuberculosis (M.tb) is believed to involve the induction of CTLs that are capable of killing cells…”
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Activation of HLA-restricted EBV-specific cytotoxic T cells does not require CD4+ (helper) T cells or exogenous cytokines by Fishwild, DM, Benike, CJ, Engleman, EG

“…MHC-restricted, viral Ag-specific "memory" CTL are thought to play a decisive role in the defense against pathogenic viruses. However, the requirements for…”
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Human T lymphocyte proliferation induced by a pan-T monoclonal antibody (anti-Leu 4): heterogeneity of response is a function of monocytes by Kaneoka, H, Perez-Rojas, G, Sasasuki, T, Benike, CJ, Engleman, EG

“…Anti-Leu-4 is a murine monoclonal antibody that defines a molecule of 20,000 to 25,000 daltons present on all mature T lymphocytes in man. When cultured in the…”
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Activation of antigen-specific suppressor T cells in the presence of cyclosporin requires interactions between T cells of inducer and suppressor lineage by MOHAGHEGHPOUR, N, BENIKE, C. J, KANSAS, G, BIEBER, C, ENGLEMAN, E. G

“…To probe the mechanism of suppressor T cell generation in man, we have carried out mixed leukocyte reactions (MLR) in the presence of cyclosporin (CsA), a…”
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Induction of immunoglobulin-secreting cells in the allogeneic mixed leukocyte reaction: regulation by helper and suppressor lymphocyte subsets in man by Kotzin, BL, Benike, CJ, Engleman, EG

“…The existence of functionally distinct T lymphocyte subsets in man, initially demonstrated with heteroantisera, has been confirmed with monoclonal reagents…”
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Autologous mixed lymphocyte reaction in patients with Hodgkin's disease. Evidence for a T cell defect by Engleman, E G, Benike, C J, Hoppe, R T, Kaplan, H S, Berberich, F R

“…The proliferative response of T lymphocytes cultured with autologous non-T lymphocytes is known as the autologous mixed lymphocyte reaction (MLR). This…”
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Cultured Human Epidermal Cells Do Not Synthesize HLA-DR by Morhenn, Vera B., Benike, Claudia J., Cox, Alvin J., Charron, Dominique J., Engleman, Edgar G.

“…All nucleated cells express HLA-A, B, and C antigens. However, only a few cells, including epidermal cells, demonstrate HLA-DR antigens which are potent…”
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Blocking of human T lymphocyte functions by anti-Leu-2 and anti-Leu-3 antibodies: differential inhibition of proliferation and suppression by Engleman, EG, Benike, CJ, Metzler, C, Gatenby, PA, Evans, RL

“…We have shown previously that monoclonal antibodies to the Leu-2 and Leu-3 T cell antigens block the response of their respective subsets in allogeneic MLR…”
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Idiotype vaccination using dendritic cells after autologous peripheral blood progenitor cell transplantation for multiple myeloma by Liso, Arcangelo, Stockerl-Goldstein, Keith E., Auffermann-Gretzinger, Susanne, Benike, Claudia J., Reichardt, Volker, van Beckhoven, Adrienne, Rajapaksa, Ranjani, Engleman, Edgar G., Blume, Karl G., Levy, Ronald

“…The idiotype (Id) determinants on the multiple myeloma immunoglobulin can serve as tumor-specific antigens. An anti-Id immune response may stem the growth of…”
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Ia antigen on peripheral blood mononuclear leukocytes in man. II. Functional studies of HLA-DR-positive T cells activated in mixed lymphocyte reactions by Engleman, E G, Benike, C J, Charron, D J

“…Blast transformation of T cells in response to allogeneic lymphocytes is followed by expression of HLA-DR antigen on up to 60% of the T cells. Murine…”
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Primed LD typing: reagent preparation and definition of the HLA-D-region antigens by Bach, F H, Jarrett-Toh, E K, Benike, C J, Shih, C Y, Valentine, E A, Sondel, P M, Bach, M L

“…Primed LD typing cells were prepared against single HLA haplotypes within families and used to type a random panel of 48 individuals. PLT cells could be…”
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Ia antigens on alloreactive T cells in man detected by monoclonal antibodies. Evidence for synthesis of HLA-D/DR molecules of the responder type by Charron, D J, Engelman, E G, Benike, C J, McDevitt, H O

“…A monoclonal antibody (Ab 2.06) directed against a nonpolymorphic determinant of HLA-D/DR molecules was used to study the expression and the biosynthesis of Ia…”
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Ia antigen on peripheral blood mononuclear leukocytes in man. I. Expression, biosynthesis, and function of HLA-DR antigen non-T cells by Engleman, E G, Charron, D J, Benike, C J, Stewart, G J

“…Murine monoclonal antibodies to monomorphic components of HLA-DR antigen were used to analyze the distribution and function of DR molecules on non-T…”
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Use of the Fluorescence-Activated Cell Sorter to Quantitate and Enrich for Subpopulations of Human Skin Cells by Morhenn, Vera B., Benike, Claudia J., Charron, Dominique J., Cox, Alvin, Mahrle, Gustav, Wood, Gary S., Engleman, Edgar G.

“…A variety of immunologic staining techniques were compared in a quantitative study of antigen expression by human epidermal cells. Virtually all nucleated…”
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