Search Results - "Benigni, Paolo"

Foci of Programmed Cell Death-Ligand 1 (PD-L1)-positive Tumor Areas With Tumor-infiltrating Leukocytes (TILs) Evocative of a PD-1/PD-L1-related Adaptive Immune Resistance are Frequent in Merkel Cell Carcinoma by Bénigni, Paolo, Guénolé, Morgan, Bonsang, Benjamin, Marcorelles, Pascale, Schick, Ulrike, Uguen, Arnaud

“…Immune checkpoint inhibitors (ICIs) targeting the programmed cell death 1 (PD-1)/programmed cell death-ligand 1 (PD-L1) axis have revolutionized the treatment…”
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Oversampling Selective Accumulation Trapped Ion Mobility Spectrometry Coupled to FT-ICR MS: Fundamentals and Applications by Benigni, Paolo, Fernandez-Lima, Francisco

“…In the present paper, we describe the fundamentals and analytical advantages of Oversampling Selective Accumulation Trapped Ion Mobility Spectrometry…”
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The prognostic significance of PD-L1 expression on tumor and immune cells in Merkel cell carcinoma by Guénolé, Morgan, Bénigni, Paolo, Bourbonne, Vincent, Lucia, François, Legoupil, Delphine, Pradier, Olivier, Misery, Laurent, Uguen, Arnaud, Schick, Ulrike

“…Introduction The aim of this study was to evaluate prognostic factors in patients with non-metastatic Merkel cell carcinoma (MCC), with a particular focus on…”
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Analysis of Photoirradiated Water Accommodated Fractions of Crude Oils Using Tandem TIMS and FT-ICR MS by Benigni, Paolo, Sandoval, Kathia, Thompson, Christopher J, Ridgeway, Mark E, Park, Melvin A, Gardinali, Piero, Fernandez-Lima, Francisco

“…For the first time, trapped ion mobility spectrometry (TIMS) in tandem with Fourier transform ion cyclotron resonance mass spectrometry (FT-ICR MS) is applied…”
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Targeted High-Resolution Ion Mobility Separation Coupled to Ultrahigh-Resolution Mass Spectrometry of Endocrine Disruptors in Complex Mixtures by Benigni, Paolo, Thompson, Christopher J, Ridgeway, Mark E, Park, Melvin A, Fernandez-Lima, Francisco

“…Traditional separation and detection of targeted compounds from complex mixtures from environmental matrices requires the use of lengthy prefractionation steps…”
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Towards Discovery and Targeted Peptide Biomarker Detection Using nanoESI-TIMS-TOF MS by Garabedian, Alyssa, Benigni, Paolo, Ramirez, Cesar E., Baker, Erin S., Liu, Tao, Smith, Richard D., Fernandez-Lima, Francisco

“…In the present work, the potential of trapped ion mobility spectrometry coupled to TOF mass spectrometry (TIMS-TOF MS) for discovery and targeted monitoring of…”
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Increasing Analytical Separation and Duty Cycle with Nonlinear Analytical Mobility Scan Functions in TIMS-FT-ICR MS by Benigni, Paolo, Porter, Jacob, Ridgeway, Mark. E, Park, Melvin. A, Fernandez-Lima, Francisco

“…In this work, nonlinear, stepping analytical mobility scan functions are implemented to increase the analytical separation and duty cycle during tandem Trapped…”
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Increasing Polyaromatic Hydrocarbon (PAH) Molecular Coverage during Fossil Oil Analysis by Combining Gas Chromatography and Atmospheric-Pressure Laser Ionization Fourier Transform Ion Cyclotron Resonance Mass Spectrometry (FT-ICR MS) by Benigni, Paolo, DeBord, J. Daniel, Thompson, Christopher J, Gardinali, Piero, Fernandez-Lima, Francisco

“…Thousands of chemically distinct compounds are encountered in fossil oil samples that require rapid screening and accurate identification. In the present…”
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Towards unsupervised polyaromatic hydrocarbons structural assignment from SA-TIMS –FTMS data by Benigni, Paolo, Marin, Rebecca, Fernandez-Lima, Francisco

“…With the advent of high resolution ion mobility analyzers and their coupling to ultrahigh resolution mass spectrometers, there is a need to further develop a…”
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Coupling trapped ion mobility spectrometry to mass spectrometry: trapped ion mobility spectrometry–time‐of‐flight mass spectrometry versus trapped ion mobility spectrometry–Fourier transform ion cyclotron resonance mass spectrometry by Tose, Lilian V., Benigni, Paolo, Leyva, Dennys, Sundberg, Abigail, Ramírez, César E., Ridgeway, Mark E., Park, Melvin A., Romão, Wanderson, Jaffé, Rudolf, Fernandez‐Lima, Francisco

“…Rationale There is a need for fast, post‐ionization separation during the analysis of complex mixtures. In this study, we evaluate the use of a high‐resolution…”
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An atypical sarcoidosis involvement in FDG PET/CT: A case report by Robin, Philippe, Benigni, Paolo, Feger, Benoit, Salaun, Pierre-Yves, Abgral, Ronan

“…Sarcoidosis is an idiopathic systemic inflammatory granulomatous disorder comprised of epithelioid and multinucleated giant cells with little necrosis which…”
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NRASQ61R and BRAFV600E Mutation-specific Immunohistochemistry Is a Helpful Tool to Diagnose Metastatic Undifferentiated/Dedifferentiated Melanomas by Uguen, Arnaud, Sassolas, Bruno, Mondine, Philippe, Doucet, Laurent, Ginestet, Florent, Benigni, Paolo, Costa, Sebastian, De Braekeleer, Marc, Marcorelles, Pascale

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Fast, ultra-trace detection of juvenile hormone III from mosquitoes using mass spectrometry by Ramirez, Cesar E., Nouzova, Marcela, Benigni, Paolo, Quirke, J. Martin E., Noriega, Fernando G., Fernandez-Lima, Francisco

“…In the present work, a new protocol for fast separation and quantification of JH III from biological samples using liquid chromatography coupled to…”
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Analysis of Geologically Relevant Metal Porphyrins Using Trapped Ion Mobility Spectrometry–Mass Spectrometry and Theoretical Calculations by Benigni, Paolo, Bravo, Carlos, Quirke, J. Martin E, DeBord, John D, Mebel, Alexander M, Fernandez-Lima, Francisco

“…The structural characterization of metal porphyrins has been traditionally challenging as a result of their large structural and compositional diversity. In…”
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Analysis of photo-irradiated water accommodated fractions of crude oils using tandem TIMS and FT-ICR MS by Benigni, Paolo, Sandoval, Kathia, Thompson, Christopher J., Ridgeway, Mark E., Park, Melvin A., Gardinali, Piero, Fernandez-Lima, Francisco

“…For the first time, trapped ion mobility spectrometry (TIMS) in tandem with Fourier transform ion cyclotron resonance mass spectrometry (FT-ICR MS) is applied…”
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An atypical sarcoidosis involvement in FDG PET/CT by Robin, Philippe, Benigni, Paolo, Feger, Benoit, Salaun, Pierre-Yves, Abgral, Ronan

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Chemical Analysis of Water-accommodated Fractions of Crude Oil Spills Using TIMS-FT-ICR MS by Benigni, Paolo, Marin, Rebecca, Sandoval, Kathia, Gardinali, Piero, Fernandez-Lima, Francisco

“…Multiple chemical processes control how crude oil is incorporated into seawater and also the chemical reactions that occur overtime. Studying this system…”
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Trapped Ion Mobility Spectrometry Coupled to Fourier Transform Ion Cyclotron Resonance Mass Spectrometry for the Analysis of Complex Mixtures by Benigni, Paolo

“…Analytical Characterization of complex mixtures, such as crude oil, environmental samples, and biological mixtures, is challenging because of the large…”
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Primary Epicardial Malt Lymphoma: A New Physiopathologic Entity Mimicking a Pericardial Compressive Syndrome by Grandmougin, Daniel, Bouhlel, Mahmoud Cheikh, Lardenois, Emilie, Donaint, Pierre, Benigni, Paolo, Sbaffi, Alessandra, Sirbu, Christina, Feugier, Pierre, Touati, Rabea, Maureira, Juan-Pablo

“…MALT lymphoma is a non-Hodgkin lymphoma developing from B cells and is a type of marginal zone lymphoma. It can develop in any organs, but no case of primary…”
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Primary Epicardial Malt Lymphoma by Grandmougin, Daniel, Bouhlel, Mahmoud Cheikh, Lardenois, Emilie, Donaint, Pierre, Benigni, Paolo, Sbaffi, Alessandra, Sirbu, Christina, Feugier, Pierre, Touati, Rabea, Maureira, Juan-Pablo

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