Search Results - "Beng, K"

Parotid-sparing intensity modulated versus conventional radiotherapy in head and neck cancer (PARSPORT): a phase 3 multicentre randomised controlled trial by Nutting, Christopher M, Dr, Morden, James P, MSc, Harrington, Kevin J, FRCR, Urbano, Teresa Guerrero, PhD, Bhide, Shreerang A, FRCR, Clark, Catharine, PhD, Miles, Elizabeth A, MPhil, Miah, Aisha B, FRCR, Newbold, Kate, FRCR, Tanay, MaryAnne, MSc, Adab, Fawzi, FRCR, Jefferies, Sarah J, FRCR, Scrase, Christopher, FRCR, Yap, Beng K, FRCR, A'Hern, Roger P, MSc, Sydenham, Mark A, BSc, Emson, Marie, BSc, Hall, Emma, PhD

“…Summary Background Xerostomia is the most common late side-effect of radiotherapy to the head and neck. Compared with conventional radiotherapy,…”
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Serendipitous synthesis of cross-conjugated dienes by cascade deconstructive esterification of thiomorpholinone-tethered alkenoic acids by Farah, Abdikani Omar, Garcia, Jorge, Borg, Claire, Beng, Timothy K

“…Functionalized 1,3-dienes are ubiquitous structural motifs in biologically pertinent molecules. They are frequently employed as precursors for a broad range of…”
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Application of Catalytic Dynamic Resolution of N-Boc-2-lithiopiperidine to the Asymmetric Synthesis of 2-Aryl and 2-Vinyl Piperidines by Beng, Timothy K., Gawley, Robert E.

“…The highly enantioselective synthesis of 2-aryl- and 2-vinyl-piperidines has been accomplished through a catalytic dynamic resolution (CDR) of…”
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Phase II trial of sorafenib in advanced salivary adenoid cystic carcinoma of the head and neck by Thomson, David J., Silva, Priyamal, Denton, Kim, Bonington, Suzanne, Mak, Soo K., Swindell, Ric, Homer, Jarrod, Sykes, Andrew J., Lee, Lip W., Yap, Beng K., Slevin, Nicholas J.

“…Background There is a need to improve the systemic treatment of advanced adenoid cystic carcinoma (ACC). Response rates to chemotherapy are poor and…”
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Management of the compromised airway and role of tracheotomy in anaplastic thyroid carcinoma by Mani, Navin, McNamara, Katherine, Lowe, Natalie, Loughran, Sean, Yap, Beng K.

“…ABSTRACT Background Anaplastic thyroid carcinoma (ATC) is an uncommon thyroid malignancy with a poor prognosis. American Thyroid Association (ATA) guidelines…”
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Synthetic Applications and Inversion Dynamics of Configurationally Stable 2‑Lithio-2-arylpyrrolidines and -piperidines by Beng, Timothy K, Woo, Jin Sun, Gawley, Robert E

“…In diethyl ether, N-Boc-2-lithio-2-arylpiperidines have been found to be configurationally stable at −80 °C, whereas N-Boc-2-lithio-2-arylpyrrolidines are…”
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O 087 - Gait patterns of patients with leg length discrepancies who had femur lengthening surgery with external fixator or intramedullary magnetic nail by Aydil, S., Sokucu, S., Beng, K., Kirat, A., Demir, B.

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Gait abnormalities in neglected adult cerebral palsy patients by Aydil, S, Beng, K, Lapcin, O, Kabukcuoglu, Y.S

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Anaplastic Thyroid Cancer: The Addition of Systemic Chemotherapy to Radiotherapy Led to an Observed Improvement in Survival—A Single Centre Experience and Review of the Literature by Yap, Beng K., Slevin, Nicholas J., Loughran, Sean, Lowe, Natalie M.

“…Introduction. Anaplastic thyroid carcinoma (ATC) is rare yet accounts for up to 50% of all thyroid cancer deaths. This study reviews outcomes of patients with…”
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CATALYTIC DYNAMIC RESOLUTION APPLIED TO THE SYNTHESIS OF 2,6-DISUBSTITUTED PIPERIDINES: PREPARATION OF (+)-LUPETIDINE AND (-)-EPIDIHYDROPINIDINE by Beng, Timothy K, Gawley, Robert E

“…The diastereoselective synthesis of trans-2,6-disubstituted piperidines has been rendered enantioselective by incorporating a catalytic dynamic resolution into…”
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What's the effectiveness of multilevel intramuscular botulinum toxin A injection in patients with spastic cerebral palsy patients in a single session? by Beng, K, Akpinar, E, Aydil, S, Bayhan, I.A, Sahin, Y, Yagmurlu, M.F

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Three-dimensional gait analysis of healthy subjects in different age groups in Turkey by Beng, K, Aydil, S, Lapcin, O, Ozkan, P, Albayrak, K, Kabukcuoglu, Y.S

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Dose intensified hypofractionated intensity-modulated radiotherapy with synchronous cetuximab for intermediate stage head and neck squamous cell carcinoma by Thomson, David J, Ho, Kean F, Ashcroft, Linda, Denton, Kim, Betts, Guy, Mais, Kathleen L, Garcez, Kate, Yap, Beng K, Lee, Lip W, Sykes, Andrew J, Rowbottom, Carl G, Slevin, Nicholas J

“…For stage II and III head and neck squamous cell carcinoma (HNSCC) treated with radiotherapy alone, loco-regional recurrence is the main cause of treatment…”
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Patterns of relapse following radiotherapy for differentiated thyroid cancer: Implication for target volume delineation by Azrif, Muhammad, Slevin, Nicholas J, Sykes, Andrew J, Swindell, Ric, Yap, Beng K

“…Abstract Introduction Post-operative residual disease in differentiated thyroid cancer is an indication for external beam radiotherapy (EBRT) especially if…”
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Cribriform-Morular Variant of Papillary Thyroid Carcinoma : Molecular Characterization of a Case With Neuroendocrine Differentiation and Aggressive Behavior by CAMESELLE-TEIJEIRO, José, MENASCE, Lia P, YAP, Beng K, COLACO, Rovel J, CASTRO, Patricia, CELESTINO, Ricardo, RUIZ-PONTE, Clara, SOARES, Paula, SOBRINHO-SIMOES, Manuel

“…We describe an especially aggressive case of cribriform-morular variant (C-MV) of papillary thyroid carcinoma (PTC) in a 42-year-old man with familial…”
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Enantiomerization Dynamics and a Catalytic Dynamic Resolution of N-Trimethylallyl-2-lithiopyrrolidine by Beng, Timothy K, Yousaf, Taher I, Coldham, Iain, Gawley, Robert E

“…The barriers to enantiomerization of N-trimethylallyl-2-lithiopyrrolidine have been measured in the presence of sparteine,1, N,N′-diisopropylbispidine, 2, and…”
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Stereocontrolled and time-honored access to piperidine- and pyrrolidine-fused 3-methylenetetrahydropyrans using lactam-tethered alkenols by Beng, Timothy K, Anosike, Ifeyinwa S, Kaur, Jasleen

“…Polycyclic oxygen-heterocycles bearing the 3-methylenetetrahydropyran ( , 3-MeTHP) motif are resident in bioactive molecules such as hodgsonox and iridoid…”
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IMRT dose fractionation for head and neck cancer: variation in current approaches will make standardisation difficult by Ho, Kean F, Fowler, Jack F, Sykes, Andrew J, Yap, Beng K, Lee, Lip W, Slevin, Nick J

“…Altered fractionation has demonstrated clinical benefits compared to the conventional 2 Gy/day standard of 70 Gy. When using synchronous chemotherapy, there is…”
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Catalytic, selective, and stereocontrolled construction of C4 quaternary and homobenzylic dihydroisoquinolones by sp C-H benzylation by Beng, Timothy K, Moreno, Antonio

“…C1 benzylated isoquinoline derivatives constitute the core of benzylisoquinoline alkaloids (BIAs). However, their C4 congeners remain elusive. Here, we…”
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Introducing a sulfone-embedded anhydride to the anhydride-imine reaction for the modular synthesis of N-heterocyclic sulfones bearing vicinal stereocenters by Beng, Timothy K, Garcia, Jorge, Eichwald, Jane, Borg, Claire

“…N-heterocyclic sulfones constitute the core of several pharmaceuticals, including the antityrpanosomal drug Nifurtimox. Their biological relevance and…”
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