Search Results - "Benford, H L"

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  1. 1

    Visualization of bisphosphonate-induced caspase-3 activity in apoptotic osteoclasts in vitro by Benford, H.L, McGowan, N.W.A, Helfrich, M.H, Nuttall, M.E, Rogers, M.J

    Published in Bone (New York, N.Y.) (01-05-2001)
    “…Bisphosphonates inhibit osteoclast-mediated bone resorption by mechanisms that have only recently become clear. Whereas nitrogen-containing bisphosphonates…”
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    Journal Article
  2. 2

    The pharmacology of bisphosphonates and new insights into their mechanisms of action by Russell, R. Graham G., Rogers, Michael J., Frith, Julie C., Luckman, Steven P., Coxon, Fraser P., Benford, Helena L., Croucher, Peter I., Shipman, Claire, Fleisch, Herbert A.

    Published in Journal of bone and mineral research (01-10-1999)
    “…Bisphosphonates are chemically stable analogs of inorganic pyrophosphate, which are resistant to breakdown by enzymatic hydrolysis. The biological effects of…”
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    Journal Article Conference Proceeding
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    Farnesol and geranylgeraniol prevent activation of caspases by aminobisphosphonates: biochemical evidence for two distinct pharmacological classes of bisphosphonate drugs by Benford, H L, Frith, J C, Auriola, S, Mönkkönen, J, Rogers, M J

    Published in Molecular pharmacology (01-07-1999)
    “…Recently, advances have been made in understanding the molecular mechanisms by which bisphosphonate drugs inhibit bone resorption. Studies with the…”
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    Journal Article
  6. 6

    Protein synthesis is required for caspase activation and induction of apoptosis by bisphosphonate drugs by Coxon, F P, Benford, H L, Russell, R G, Rogers, M J

    Published in Molecular pharmacology (01-10-1998)
    “…The exact mechanisms of action of antiresorptive bisphosphonate drugs remain unclear, although they may inhibit bone resorption by mechanisms that can lead to…”
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    Journal Article
  7. 7

    Cellular and molecular mechanisms of action of bisphosphonates by Rogers, Michael J., Gordon, S., Benford, H. L., Coxon, F. P., Luckman, S. P., Monkkonen, J., Frith, J. C.

    Published in Cancer (15-06-2000)
    “…BACKGROUND Bisphosphonates currently are the most important class of antiresorptive agents used in the treatment of metabolic bone diseases, including…”
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    Journal Article
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