Search Results - "Benešová, Martina"

Albumin-Binding PSMA Ligands: Optimization of the Tissue Distribution Profile by Benešová, Martina, Umbricht, Christoph A, Schibli, Roger, Müller, Cristina

“…The prostate-specific membrane antigen (PSMA) has emerged as an attractive prostate cancer associated target for radiotheragnostic application using…”
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Preclinical Development of Novel PSMA-Targeting Radioligands: Modulation of Albumin-Binding Properties To Improve Prostate Cancer Therapy by Umbricht, Christoph A, Benešová, Martina, Schibli, Roger, Müller, Cristina

“…The treatment of metastatic castration-resistant prostate cancer (mCRPC) remains challenging with current treatment options. The development of more effective…”
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Preclinical Evaluation of a Tailor-Made DOTA-Conjugated PSMA Inhibitor with Optimized Linker Moiety for Imaging and Endoradiotherapy of Prostate Cancer by Benešová, Martina, Schäfer, Martin, Bauder-Wüst, Ulrike, Afshar-Oromieh, Ali, Kratochwil, Clemens, Mier, Walter, Haberkorn, Uwe, Kopka, Klaus, Eder, Matthias

“…Despite many advances in the past years, the treatment of metastatic prostate cancer still remains challenging. In recent years, prostate-specific membrane…”
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Linker Modification Strategies To Control the Prostate-Specific Membrane Antigen (PSMA)-Targeting and Pharmacokinetic Properties of DOTA-Conjugated PSMA Inhibitors by Benešová, Martina, Bauder-Wüst, Ulrike, Schäfer, Martin, Klika, Karel D, Mier, Walter, Haberkorn, Uwe, Kopka, Klaus, Eder, Matthias

“…Since prostate-specific membrane antigen (PSMA) is up-regulated in nearly all stages of prostate cancer (PCa), PSMA can be considered as a viable diagnostic…”
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Glu-Ureido-Based Inhibitors of Prostate-Specific Membrane Antigen: Lessons Learned During the Development of a Novel Class of Low-Molecular-Weight Theranostic Radiotracers by Kopka, Klaus, Benešová, Martina, Bařinka, Cyril, Haberkorn, Uwe, Babich, John

“…In recent years, several radioligands targeting prostate-specific membrane antigen (PSMA) have been clinically introduced as a new class of theranostic…”
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Atomic Nanogenerators in Targeted Alpha Therapies: Curie's Legacy in Modern Cancer Management by Roscher, Mareike, Bakos, Gábor, Benešová, Martina

“…Atomic in vivo nanogenerators such as actinium-225, thorium-227, and radium-223 are of increasing interest and importance in the treatment of patients with…”
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Are there fractals in sign language? by Andres, Jan, Benešová, Martina, Fišerová, Eva, Langer, Jiří

“…Sign language is analyzed from the perspective of Menzerath-Altmann law (MAL). In reply to a question posed in the title, this study involves a comprehensive…”
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Biodistribution and dosimetry of a single dose of albumin-binding ligand [177Lu]Lu-PSMA-ALB-56 in patients with mCRPC by Kramer, Vasko, Fernández, René, Lehnert, Wencke, Jiménez-Franco, Luis David, Soza-Ried, Cristian, Eppard, Elisabeth, Ceballos, Matias, Meckel, Marian, Benešová, Martina, Umbricht, Christoph A., Kluge, Andreas, Schibli, Roger, Zhernosekov, Konstantin, Amaral, Horacio, Müller, Cristina

“…Introduction PSMA-targeted radionuclide therapy with lutetium-177 has emerged as an effective treatment option for metastatic, castration-resistant prostate…”
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Preclinical Comparison of Albumin-Binding Radiofolates: Impact of Linker Entities on the in Vitro and in Vivo Properties by Siwowska, Klaudia, Haller, Stephanie, Bortoli, Francesca, Benešová, Martina, Groehn, Viola, Bernhardt, Peter, Schibli, Roger, Müller, Cristina

“…Tumor targeting with folic acid radioconjugates has been proposed as a promising strategy for radionuclide therapy of folate receptor α (FR)-positive cancer…”
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Synthesis, Radiolabeling, and Characterization of Plasma Protein-Binding Ligands: Potential Tools for Modulation of the Pharmacokinetic Properties of (Radio)Pharmaceuticals by Müller, Cristina, Farkas, Renáta, Borgna, Francesca, Schmid, Raffaella M, Benešová, Martina, Schibli, Roger

“…The development of (radio)­pharmaceuticals with favorable pharmacokinetic profiles is crucial for allowing the optimization of the imaging or therapeutic…”
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Design and Evaluation of Novel Albumin-Binding Folate Radioconjugates: Systematic Approach of Varying the Linker Entities by Benešová, Martina, Guzik, Patrycja, Deberle, Luisa M, Busslinger, Sarah D, Landolt, Tanja, Schibli, Roger, Müller, Cristina

“…Tumor targeting using folate radioconjugates is a promising strategy for theragnostics of folate receptor-positive tumors. The aim of this study was to…”
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Metastatic Spread in Prostate Cancer Patients Influencing Radiotherapy Response by Klusa, Daria, Lohaus, Fabian, Furesi, Giulia, Rauner, Martina, Benešová, Martina, Krause, Mechthild, Kurth, Ina, Peitzsch, Claudia

“…Radiotherapy and surgery are curative treatment options for localized prostate cancer (PCa) with a 5-year survival rate of nearly 100%. Once PCa cells spread…”
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Novel Synthetic Strategies Enable the Efficient Development of Folate Conjugates for Cancer Radiotheranostics by Deberle, Luisa M, Benešová, Martina, Becker, Anna E, Ratz, Magdalena, Guzik, Patrycja, Schibli, Roger, Müller, Cristina

“…The folate receptor (FR) is an interesting target for radiotheranostics due to its overexpression in several tumor types. The progress in developing novel…”
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Development of a new class of PSMA radioligands comprising ibuprofen as an albumin-binding entity by Deberle, Luisa M, Benešová, Martina, Umbricht, Christoph A, Borgna, Francesca, Büchler, Manuel, Zhernosekov, Konstantin, Schibli, Roger, Müller, Cristina

“…Prostate-specific membrane antigen (PSMA)-targeted radioligands have been used for the treatment of metastatic castration-resistant prostate cancer (mCRPC)…”
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Preclinical evaluation of 5-methyltetrahydrofolate-based radioconjugates—new perspectives for folate receptor–targeted radionuclide therapy by Guzik, Patrycja, Benešová, Martina, Ratz, Magdalena, Monné Rodríguez, Josep M., Deberle, Luisa M., Schibli, Roger, Müller, Cristina

“…Purpose The folate receptor (FR) is frequently overexpressed in a variety of tumor types and, hence, an interesting target for radionuclide therapy. The aim of…”
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44Sc-PSMA-617 for radiotheragnostics in tandem with 177Lu-PSMA-617—preclinical investigations in comparison with 68Ga-PSMA-11 and 68Ga-PSMA-617 by Umbricht, Christoph A., Benešová, Martina, Schmid, Raffaella M., Türler, Andreas, Schibli, Roger, van der Meulen, Nicholas P., Müller, Cristina

“…Background The targeting of the prostate-specific membrane antigen (PSMA) is of particular interest for radiotheragnostic purposes of prostate cancer…”
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Towards a Fractal Analysis of the Sign Language by Andres, Jan, Benešová, Martina, Langer, Jiří

“…In this paper, it is the first attempt to discuss and explore a possible extension of Hřebíček's conjecture about a fractal structure of language from a…”
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Identification of a PET Radiotracer for Imaging of the Folate Receptor-α: A Potential Tool to Select Patients for Targeted Tumor Therapy by Guzik, Patrycja, Fang, Hsin-Yu, Deberle, Luisa M, Benešová, Martina, Cohrs, Susan, Boss, Silvan D, Ametamey, Simon M, Schibli, Roger, Müller, Cristina

“…The aim of this study was to identify a folate receptor-α (FRα)-selective PET agent potentially suitable for the selection of patients who might profit from…”
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Conference Report QUALICO 2014, Olomouc 29th May-1st June 2014, Czech Republic by Benešová, Martina

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[68Ga]Ga-DOTA-TOC: The First FDA-Approved 68Ga-Radiopharmaceutical for PET Imaging by Hennrich, Ute, Benešová, Martina

“…In the United States, [68Ga]Ga-DOTA-TOC has been approved by the Food and Drug Administration (FDA) in 2019 as the first 68Ga-radiopharmaceutical for imaging…”
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