Search Results - "Beneker, Chad M."

A new fluorescent sensor mitoferrofluor indicates the presence of chelatable iron in polarized and depolarized mitochondria by Kholmukhamedov, Andaleb, Li, Li, Lindsey, Christopher C., Hu, Jiangting, Nieminen, Anna-Liisa, Takemoto, Kenji, Beeson, Gyda C., Beneker, Chad M., McInnes, Campbell, Beeson, Craig C., Lemasters, John J.

“…Mitochondrial chelatable iron contributes to the severity of several injury processes, including ischemia/reperfusion, oxidative stress, and drug toxicity…”
Get full text

Design and Synthesis of Type-IV Inhibitors of BRAF Kinase That Block Dimerization and Overcome Paradoxical MEK/ERK Activation by Beneker, Chad M, Rovoli, Magdalini, Kontopidis, George, Röring, Michael, Galda, Simeon, Braun, Sandra, Brummer, Tilman, McInnes, Campbell

“…Despite the clinical success of BRAF inhibitors like vemurafenib in treating metastatic melanoma, resistance has emerged through “paradoxical MEK/ERK…”
Get full text