Search Results - "Benegiamo, Giorgia"

Diurnal transcriptome atlas of a primate across major neural and peripheral tissues by Mure, Ludovic S, Le, Hiep D, Benegiamo, Giorgia, Chang, Max W, Rios, Luis, Jillani, Ngalla, Ngotho, Maina, Kariuki, Thomas, Dkhissi-Benyahya, Ouria, Cooper, Howard M, Panda, Satchidananda

“…Diurnal gene expression patterns underlie time-of-the-day-specific functional specialization of tissues. However, available circadian gene expression atlases…”
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Genetic and dietary modulators of the inflammatory response in the gastrointestinal tract of the BXD mouse genetic reference population by Li, Xiaoxu, Morel, Jean-David, Benegiamo, Giorgia, Poisson, Johanne, Bachmann, Alexis, Rapin, Alexis, Sulc, Jonathan, Williams, Evan, Perino, Alessia, Schoonjans, Kristina, Bou Sleiman, Maroun, Auwerx, Johan

“…Inflammatory gut disorders, including inflammatory bowel disease (IBD), can be impacted by dietary, environmental, and genetic factors. While the incidence of…”
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Sodium ferrous citrate and 5‐aminolevulinic acid improve type 2 diabetes by maintaining muscle and mitochondrial health by Kitamura, Naho, Zhang, Shiyang, Morel, Jean‐David, Nagano, Utana, Taworntawat, Tanon, Hosoda, Shotaro, Nakamura, Anna, Ogawa, Yoko, Benegiamo, Giorgia, Auwerx, Johan, Tsubota, Kazuo, Yokoyama, Yoko, Watanabe, Mitsuhiro

“…Objective Improving mitochondrial function is a promising strategy for intervention in type 2 diabetes mellitus. This study investigated the preventive effects…”
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ARNTL2 and SERPINE1: potential biomarkers for tumor aggressiveness in colorectal cancer by Mazzoccoli, Gianluigi, Pazienza, Valerio, Panza, Anna, Valvano, Maria Rosa, Benegiamo, Giorgia, Vinciguerra, Manlio, Andriulli, Angelo, Piepoli, Ada

“…Purpose Cathepsin and plasmin may favor cancer cell invasion degrading extracellular matrix. Plasmin formation from plasminogen is regulated by plasminogen…”
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DNA Methyltransferases 1 and 3b Expression in Huh-7 Cells Expressing HCV Core Protein of Different Genotypes by Benegiamo, Giorgia, Vinciguerra, Manlio, Mazzoccoli, Gianluigi, Piepoli, Ada, Andriulli, Angelo, Pazienza, Valerio

“…Background Hepatitis C virus infects ~3 % of the population and it is a risk factor for hepatocarcinogenesis. The epigenetic mechanisms of HCV-induced…”
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Mutual antagonism between circadian protein period 2 and hepatitis C virus replication in hepatocytes by Benegiamo, Giorgia, Mazzoccoli, Gianluigi, Cappello, Francesco, Rappa, Francesca, Scibetta, Nunzia, Oben, Jude, Greco, Azzura, Williams, Roger, Andriulli, Angelo, Vinciguerra, Manlio, Pazienza, Valerio

“…Hepatitis C virus (HCV) infects approximately 3% of the world population and is the leading cause of liver disease, impacting hepatocyte metabolism, depending…”
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Altered expression of the clock gene machinery in kidney cancer patients by Mazzoccoli, Gianluigi, Piepoli, Ada, Carella, Massimo, Panza, Anna, Pazienza, Valerio, Benegiamo, Giorgia, Palumbo, Orazio, Ranieri, Elena

“…Abstract Background and aim Kidney cancer is associated with alteration in the pathways regulated by von Hippel-Lindau protein and hypoxia inducible factor α…”
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Genetic background and sex control the outcome of high-fat diet feeding in mice by Bachmann, Alexis Maximilien, Morel, Jean-David, El Alam, Gaby, Rodríguez-López, Sandra, Imamura de lima, Tanes, Goeminne, Ludger J.E., Benegiamo, Giorgia, Loric, Sylvain, Conti, Marc, Sleiman, Maroun Bou, Auwerx, Johan

“…The sharp increase in obesity prevalence worldwide is mainly attributable to changes in physical activity and eating behavior but the metabolic and clinical…”
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Differential patterns in the periodicity and dynamics of clock gene expression in mouse liver and stomach by Mazzoccoli, Gianluigi, Francavilla, Massimo, Pazienza, Valerio, Benegiamo, Giorgia, Piepoli, Ada, Vinciguerra, Manlio, Giuliani, Francesco, Yamamoto, Takuro, Takumi, Toru

“…The rhythmic recurrence of biological processes is driven by the functioning of cellular circadian clocks, operated by a set of genes and proteins that…”
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Asperuloside Improves Obesity and Type 2 Diabetes through Modulation of Gut Microbiota and Metabolic Signaling by Nakamura, Anna, Yokoyama, Yoko, Tanaka, Kazuki, Benegiamo, Giorgia, Hirayama, Akiyoshi, Zhu, Qi, Kitamura, Naho, Sugizaki, Taichi, Morimoto, Kohkichi, Itoh, Hiroshi, Fukuda, Shinji, Auwerx, Johan, Tsubota, Kazuo, Watanabe, Mitsuhiro

“…Asperuloside (ASP) is an iridoid glycoside that is extracted from Eucommia leaves. Eucommia is used in traditional Chinese medicine and has a long history of…”
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Correlations among PPARγ, DNMT1, and DNMT3B Expression Levels and Pancreatic Cancer by Pazienza, Valerio, Tavano, Francesca, Benegiamo, Giorgia, Vinciguerra, Manlio, Burbaci, Francesca Paola, Copetti, Massimiliano, di Mola, Fabio Francesco, Andriulli, Angelo, di Sebastiano, Pierluigi

“…Emerging evidence indicates that peroxisome proliferator-activated receptor γ (PPARγ) and DNA methyltransferases (DNMTs) play a role in carcinogenesis. In this…”
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Time-Qualified Patterns of Variation of PPARγ, DNMT1, and DNMT3B Expression in Pancreatic Cancer Cell Lines by Pazienza, Valerio, Tavano, Francesca, Francavilla, Massimo, Fontana, Andrea, Pellegrini, Fabio, Benegiamo, Giorgia, Corbo, Vincenzo, di Mola, Fabio Francesco, di Sebastiano, Pierluigi, Andriulli, Angelo, Mazzoccoli, Gianluigi

“…Carcinogenesis is related to the loss of homeostatic control of cellular processes regulated by transcriptional circuits and epigenetic mechanisms. Among…”
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Correlations among PPAR, DNMT1, and DNMT3B Expression Levels and Pancreatic Cancer by Pazienza, Valerio, Tavano, Francesca, Benegiamo, Giorgia, Vinciguerra, Manlio, Burbaci, Francesca Paola, Copetti, Massimiliano, di Mola, Fabio Francesco, Andriulli, Angelo, di Sebastiano, Pierluigi

“…Emerging evidence indicates that peroxisome proliferator-activated receptor γ (PPAR γ ) and DNA methyltransferases (DNMTs) play a role in carcinogenesis. In…”
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Gene replacement therapy provides benefit in an adult mouse model of Leigh syndrome by Reynaud-Dulaurier, Robin, Benegiamo, Giorgia, Marrocco, Elena, Al-Tannir, Racha, Surace, Enrico Maria, Auwerx, Johan, Decressac, Michael

“…Mutations in nuclear-encoded mitochondrial genes are responsible for a broad spectrum of disorders among which Leigh syndrome is the most common in infancy. No…”
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The RNA-Binding Protein NONO Coordinates Hepatic Adaptation to Feeding by Benegiamo, Giorgia, Mure, Ludovic S., Erikson, Galina, Le, Hiep D., Moriggi, Ermanno, Brown, Steven A., Panda, Satchidananda

“…The mechanisms by which feeding and fasting drive rhythmic gene expression for physiological adaptation to daily rhythm in nutrient availability are not well…”
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Wars1 downregulation in hepatocytes induces mitochondrial stress and disrupts metabolic homeostasis by Pontanari, Francesca, Demagny, Hadrien, Faure, Adrien, Li, Xiaoxu, Benegiamo, Giorgia, Jalil, Antoine, Perino, Alessia, Auwerx, Johan, Schoonjans, Kristina

“…Several laboratories, including ours, have employed the Slc25a47tm1c(EUCOMM)Hmgu mouse model to investigate the role of SLC25A47, a hepatocyte-specific…”
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Sustained Melanopsin Photoresponse Is Supported by Specific Roles of β-Arrestin 1 and 2 in Deactivation and Regeneration of Photopigment by Mure, Ludovic S., Hatori, Megumi, Ruda, Kiersten, Benegiamo, Giorgia, Demas, James, Panda, Satchidananda

“…Melanopsin-expressing intrinsically photosensitive retinal ganglion cells (ipRGCs) are indispensable for non-image-forming visual responses that sustain under…”
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RNA Dynamics in the Control of Circadian Rhythm by Benegiamo, Giorgia, Brown, Steven A, Panda, Satchidananda

“…The circadian oscillator is based on transcription-translation feedback loops that generate 24 h oscillations in gene expression. Although circadian regulation…”
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The genetic background shapes the susceptibility to mitochondrial dysfunction and NASH progression by Benegiamo, Giorgia, von Alvensleben, Giacomo V G, Rodríguez-López, Sandra, Goeminne, Ludger J E, Bachmann, Alexis M, Morel, Jean-David, Broeckx, Ellen, Ma, Jing Ying, Carreira, Vinicius, Youssef, Sameh A, Azhar, Nabil, Reilly, Dermot F, D'Aquino, Katharine, Mullican, Shannon, Bou-Sleiman, Maroun, Auwerx, Johan

“…Non-alcoholic steatohepatitis (NASH) is a global health concern without treatment. The challenge in finding effective therapies is due to the lack of good…”
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Genetic and dietary modulators of the inflammatory response in the gastrointestinal tract of the BXD mouse genetic reference population by Li, Xiaoxu, Morel, Jean-David, Benegiamo, Giorgia, Poisson, Johanne, Bachmann, Alexis, Rapin, Alexis, Sulc, Jonathan, Williams, Evan, Perino, Alessia, Schoonjans, Kristina, Bou Sleiman, Maroun, Auwerx, Johan

“…Inflammatory gut disorders, including inflammatory bowel disease (IBD), can be impacted by dietary, environmental, and genetic factors. While the incidence of…”
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