Search Results - "Benedeković, Goran"

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  1. 1

    Synthesis and antiproliferative activity of (−)-cleistenolide, (6S)-cleistenolide and 4-substituted cleistenolide analogues by Benedeković, Goran, Farkas, Sándor, Popsavin, Mirjana, Stanisavljević, Sladjana, Djokić, Sanja, Francuz, Jovana, Kojić, Vesna, Popsavin, Velimir

    Published in Bioorganic & medicinal chemistry (01-09-2024)
    “…Nineteen new analogues of (−)-cleistenolide were designed, synthesized and evaluated for their in vitro antitumour activity. [Display omitted] •A simple total…”
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  2. 2

    Asymmetric synthesis and biological evaluation of (+)-cardiobutanolide, (−)-3-deoxycardiobutanolide and analogues as antiproliferative agents by Kovačević, Ivana, Kesić, Jelena, Popsavin, Mirjana, Francuz, Jovana, Kojić, Vesna, Jakimov, Dimitar, Rodić, Marko V., Zelenović, Bojana Srećo, Benedeković, Goran, Popsavin, Velimir

    Published in Tetrahedron (24-09-2021)
    “…Two natural products, (+)-cardiobutanolide and (−)-3-deoxycardiobutanolide, as well as five new analogues, were synthesized in several steps that included…”
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  3. 3

    Synthesis and antiproliferative activity of (5R)-cleistenolide and analogues by Farkas, Sándor, Benedekovic, Goran, Stanisavljevic, Sladjana, Sreco-Zelenovic, Bojana, Popsavin, Mirjana, Popsavin, Velimir, Jakimov, Dimitar

    “…(5R)-Cleistenolide and a few related analogues have been synthesized starting from d-glucose. The key steps of the synthesis included a Z-selective Wittig…”
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  4. 4

    The first total synthesis and revision of absolute stereochemistry of natural cytotoxic lactone cleistanolate by Kesić, Jelena, Kovačević, Ivana, Popsavin, Mirjana, Benedeković, Goran, Rodić, Marko V., Kojić, Vesna, Popsavin, Velimir

    Published in Bioorganic chemistry (01-11-2022)
    “…[Display omitted] •The first total synthesis of the natural product Cleistanolate was achieved.•The proposed structure of the natural product was…”
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  5. 5

    Conformationally restricted goniofufurone mimics with halogen, azido or benzoyloxy groups at the C-7 position: Design, synthesis and antiproliferative activity by Svirčev, Miloš, Benedeković, Goran, Kovačević, Ivana, Popsavin, Mirjana, Kojić, Vesna, Jakimov, Dimitar, Srdić-Rajić, Tatjana, Rodić, Marko V., Popsavin, Velimir

    Published in Tetrahedron (06-09-2018)
    “…A series of new conformationally restricted goniofufurone mimics, bearing an additional 1,3-dioxan ring and a halogen, azido or benzoyloxy functionality at the…”
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  6. 6

    New antitumour agents with α,β-unsaturated δ-lactone scaffold: Synthesis and antiproliferative activity of (−)-cleistenolide and analogues by Benedeković, Goran, Kovačević, Ivana, Popsavin, Mirjana, Francuz, Jovana, Kojić, Vesna, Bogdanović, Gordana, Popsavin, Velimir

    Published in Bioorganic & medicinal chemistry letters (15-07-2016)
    “…[Display omitted] A stereoselective total synthesis of (−)-cleistenolide (1) from d-glucose has been achieved. This new approach for the synthesis of…”
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  7. 7

    Divergent Synthesis of Cytotoxic Styryl Lactones Related to Goniobutenolides A and B, and to Crassalactone D by Popsavin, Velimir, Kovačević, Ivana, Benedeković, Goran, Popsavin, Mirjana, Kojić, Vesna, Bogdanović, Gordana

    Published in Organic letters (07-12-2012)
    “…Goniobutenolides A (1) and B (2), crassalactone D (3), 4-epi-crassalactone D (4), and the corresponding 7-epimers have been synthesized starting from…”
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  8. 8

    Novel (−)-goniofufurone mimics: Synthesis, antiproliferative activity and SAR analysis by Sreco-Zelenovic, Bojana, Kekezovic, Sladjana, Popsavin, Mirjana, Kojic, Vesna, Benedekovic, Goran, Popsavin, Velimir

    “…Divergent syntheses of novel (?)-goniofufurone mimics with an alkoxymethyl group as the side chain have been accomplished from D-glucose in nine synthetic…”
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  9. 9

    Synthesis and in vitro antitumour activity of crassalactone D, its stereoisomers and novel cinnamic ester derivatives by Kovačević, Ivana, Popsavin, Mirjana, Benedeković, Goran, Kesić, Jelena, Kojić, Vesna, Jakimov, Dimitar, Srdić-Rajić, Tatjana, Bogdanović, Gordana, Divjaković, Vladimir, Popsavin, Velimir

    Published in European journal of medicinal chemistry (07-07-2017)
    “…Naturally occurring styryl lactone, crassalactone D (1), unnatural 4-epi-crassalactone D (2), and the corresponding 7-epimers (3 and 4) have been synthesized…”
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  10. 10

    Design, synthesis and SAR analysis of antitumour styryl lactones related to (+)-crassalactones B and C by Benedeković, Goran, Popsavin, Mirjana, Francuz, Jovana, Kovačević, Ivana, Kojić, Vesna, Bogdanović, Gordana, Divjaković, Vladimir, Popsavin, Velimir

    Published in European journal of medicinal chemistry (24-11-2014)
    “…A series of styryl lactones containing the cinnamic acid ester groups such as (+)-crassalactones B (3a) and C (4a), 5,7-di-O-cinamoyl derivative 6, the…”
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    Conformationally constrained goniofufurone mimics as inhibitors of tumour cells growth: Design, synthesis and SAR study by Benedeković, Goran, Francuz, Jovana, Kovačević, Ivana, Popsavin, Mirjana, Zelenović, Bojana Srećo, Kojić, Vesna, Bogdanović, Gordana, Divjaković, Vladimir, Popsavin, Velimir

    Published in European journal of medicinal chemistry (23-07-2014)
    “…Synthesis of conformationally restricted (+)-goniofufurone (1) and 7-epi-(+)-goniofufurone (2) analogues, with embedded O-isopropylidene, O-methylidene or…”
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  14. 14
  15. 15

    Enantiodivergent synthesis of cytotoxic styryl lactones from d-xylose. The first total synthesis of (+)- and (−)-crassalactone C by Popsavin, Velimir, Benedeković, Goran, Srećo, Bojana, Francuz, Jovana, Popsavin, Mirjana, Kojić, Vesna, Bogdanović, Gordana, Divjaković, Vladimir

    Published in Tetrahedron (19-12-2009)
    “…Enantiodivergent total syntheses of both (+)- and (−)-enantiomers of goniofufurone, 7- epi-goniofufurone and crassalactone C have been accomplished starting…”
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  16. 16

    Heteroannelated and 7-deoxygenated goniofufurone mimics with antitumour activity: Design, synthesis and preliminary SAR studies by Popsavin, Velimir, Francuz, Jovana, Srećo Zelenović, Bojana, Benedeković, Goran, Popsavin, Mirjana, Kojić, Vesna, Bogdanović, Gordana

    Published in Bioorganic & medicinal chemistry letters (15-10-2013)
    “…Cytotoxic (+)-goniofufurone mimic such as benzoxepane 2 was preferentially formed after the treatment of 7-O-benzoyl-5-O-benzyl (+)-goniofufurone derivative 6…”
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  17. 17

    Novel goniofufurone and 7-epi-goniofufurone mimics from an unexpected titanium-mediated displacement process by Francuz, Jovana, Srećo, Bojana, Popsavin, Mirjana, Benedeković, Goran, Divjaković, Vladimir, Kojić, Vesna, Bogdanović, Gordana, Kapor, Agneš, Popsavin, Velimir

    Published in Tetrahedron letters (04-04-2012)
    “…The synthesis and preliminary antitumour screening of several new goniofufurone mimics bearing chloride and bromide substituents at C-7 are described…”
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  18. 18

    Heteroannelated (+)-muricatacin mimics: synthesis, antiproliferative properties and structure–activity relationships by Srećo, Bojana, Benedeković, Goran, Popsavin, Mirjana, Hadžić, Pavle, Kojić, Vesna, Bogdanović, Gordana, Divjaković, Vladimir, Popsavin, Velimir

    Published in Tetrahedron (02-12-2011)
    “…Six new (+)-muricatacin mimics bearing a furano-furanone core have been synthesized and their in vitro antiproliferative activity was evaluated against a panel…”
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  19. 19

    Chromatographic lipophilicity and pharmacokinetic behavior of some newly synthesized styryl lactone stereoisomers by Lоnčаr Dаvоr М., Мilоšеvić Nаtаšа P., Vitas Jasmina S., Karadžić Milica Ž., Jevrić Lidija R., Benedeković Goran

    Published in Acta Periodica Technologica (01-01-2017)
    “…The RP-HPLC retention constants of several newly synthesized cytotoxic styryl lactone stereoisomers were determined as parameters of their lipophilicity…”
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  20. 20

    Synthesis, antiproliferative activity and SAR analysis of (−)-cleistenolide and analogues by Benedeković, Goran, Popsavin, Mirjana, Kovačević, Ivana, Kojić, Vesna, Rodić, Marko, Popsavin, Velimir

    Published in European journal of medicinal chemistry (15-09-2020)
    “…A new, modified total synthesis of (−)-cleistenolide (1) and sixteen new analogues or derivatives was achieved starting from commercially available…”
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