Search Results - "Benedé‐Ubieto, Raquel"
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The Lieber‐DeCarli Diet—A Flagship Model for Experimental Alcoholic Liver Disease
Published in Alcoholism, clinical and experimental research (01-10-2018)“…Alcoholic liver disease (ALD) is the most common chronic liver disease in the Western world, and it persists at a high prevalence. Understanding the…”
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Fecal microbiota transplantation from female donors restores gut permeability and reduces liver injury and inflammation in middle-aged male mice exposed to alcohol
Published in Frontiers in nutrition (Lausanne) (18-04-2024)“…Alcohol misuse, binge drinking pattern, and gender-specific effects in the middle-aged population has been clearly underestimated. In the present study, we…”
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An Experimental DUAL Model of Advanced Liver Damage
Published in Hepatology communications (01-06-2021)“…Individuals exhibiting an intermediate alcohol drinking pattern in conjunction with signs of metabolic risk present clinical features of both…”
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Fat: Quality, or Quantity? What Matters Most for the Progression of Metabolic Associated Fatty Liver Disease (MAFLD)
Published in Biomedicines (22-09-2021)“…Objectives: Lately, many countries have restricted or even banned transfat, and palm oil has become a preferred replacement for food manufacturers. Whether…”
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Guidelines and Considerations for Metabolic Tolerance Tests in Mice
Published in Diabetes, metabolic syndrome and obesity (01-02-2020)“…The epidemic of the century, Diabetes Mellitus (DM) is continuously rising. Intensive research is urgently needed whereby experimental models represent an…”
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Breaking the barriers: the role of gut homeostasis in Metabolic-Associated Steatotic Liver Disease (MASLD)
Published in Gut microbes (2024)“…Obesity, insulin resistance (IR), and the gut microbiome intricately interplay in Metabolic-associated Steatotic Liver Disease (MASLD), previously known as…”
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The outcome of boosting mitochondrial activity in alcohol-associated liver disease is organ-dependent
Published in Hepatology (Baltimore, Md.) (01-09-2023)“…Alcohol-associated liver disease (ALD) accounts for 70% of liver-related deaths in Europe, with no effective approved therapies. Although mitochondrial…”
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Lack of Cyclin E1 in hepatocytes aggravates ethanol-induced liver injury and hepatic steatosis in experimental murine model of acute and chronic alcohol-associated liver disease
Published in Biochimica et biophysica acta. Molecular basis of disease (01-04-2023)“…Cyclin E1 is the regulatory subunit of cyclin-dependent kinase 2 (Cdk2) and one of the central players in cell cycle progression. We recently showed its…”
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A Shortcut from Metabolic-Associated Fatty Liver Disease (MAFLD) to Hepatocellular Carcinoma (HCC): c-MYC a Promising Target for Preventative Strategies and Individualized Therapy
Published in Cancers (31-12-2021)“…Metabolic-associated fatty liver disease (MAFLD) has risen as one of the leading etiologies for hepatocellular carcinoma (HCC). Oncogenes have been suggested…”
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Abnormal Liver Function Test in Patients Infected with Coronavirus (SARS-CoV-2): A Retrospective Single-Center Study from Spain
Published in Journal of clinical medicine (03-03-2021)“…The outbreak of the novel coronavirus SARS-CoV-2 epidemic has rapidly spread and still poses a serious threat to healthcare systems worldwide. In the present…”
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WED-528-YI Isolation and characterization of extracellular vesicles in faecal matter: implications for future biomarker discovery
Published in Journal of hepatology (01-06-2024)Get full text
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Loss of Cdkn1a protects against MASLD alone or with alcohol intake by preserving lipid homeostasis
Published in JHEP reports (01-10-2024)Get full text
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