Search Results - "Bendzick, Laura E"
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A dominantly acting murine allele of Mcm4 causes chromosomal abnormalities and promotes tumorigenesis
Published in PLoS genetics (01-11-2012)“…Here we report the isolation of a murine model for heritable T cell lymphoblastic leukemia/lymphoma (T-ALL) called Spontaneous dominant leukemia (Sdl). Sdl…”
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Reverse Translation Identifies the Synergistic Role of Immune Checkpoint Blockade and IL15 to Enhance Immunotherapy of Ovarian Cancer
Published in Cancer immunology research (03-05-2023)“…Immune checkpoint blockade (ICB) has changed the standard of care for many patients with cancer, yet no ICB is approved for ovarian cancer. We hypothesized…”
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Whole-body sleeping beauty mutagenesis can cause penetrant leukemia/lymphoma and rare high-grade glioma without associated embryonic lethality
Published in Cancer research (Chicago, Ill.) (01-11-2009)“…The Sleeping Beauty (SB) transposon system has been used as a somatic mutagen to identify candidate cancer genes. In previous studies, efficient…”
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Journal Article