Search Results - "Bendová, Petra"
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Methyl and ethyl ketone analogs of salicylaldehyde isonicotinoyl hydrazone: Novel iron chelators with selective antiproliferative action
Published in Chemico-biological interactions (30-05-2012)“…[Display omitted] ► New analogs of aroylhydrazone iron chelator SIH examined for antiproliferative action. ► Higher toxicity observed towards the cancer cell…”
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Current requirements for early hearing detection and intervention at bilateral congenital profound hearing loss
Published in Listy klinické logopedie (14-12-2019)“…Bilateral congenital hearing impairment is a serious lifelong handicap for the disabled child, especially due to the limited reception of information,…”
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MRI-based registration of pelvic alignment affected by altered pelvic floor muscle characteristics
Published in Clinical biomechanics (Bristol) (01-11-2007)“…Abstract Background Pelvic floor muscles have potential to influence relative pelvic alignment. Side asymmetry in pelvic floor muscle tension is claimed to…”
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Mutational analysis of driver genes defines the colorectal adenoma: in situ carcinoma transition
Published in Scientific reports (16-02-2022)“…A large proportion of colorectal carcinomas (CRC) evolve from colorectal adenomas. However, not all individuals with colonic adenomas have a risk of CRC…”
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Author Correction: Mutational analysis of driver genes defines the colorectal adenoma: in situ carcinoma transition
Published in Scientific reports (04-04-2022)Get full text
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Author Correction: Mutational analysis of driver genes defines the colorectal adenoma: in situ carcinoma transition
Published in Scientific reports (21-10-2022)Get full text
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The Associations of Selenoprotein Genetic Variants with the Risks of Colorectal Adenoma and Colorectal Cancer: Case–Control Studies in Irish and Czech Populations
Published in Nutrients (29-06-2022)“…Background: Selenium manifests its biological effects through its incorporation into selenoproteins, which play several roles in countering oxidative and…”
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Genetic variations in microRNA-binding sites of solute carrier transporter genes as predictors of clinical outcome in colorectal cancer
Published in Carcinogenesis (New York) (17-04-2021)“…One of the principal mechanisms of chemotherapy resistance in highly frequent solid tumors, such as colorectal cancer (CRC), is the decreased activity of drug…”
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Polymorphisms in microRNA binding sites of mucin genes as predictors of clinical outcome in colorectal cancer patients
Published in Carcinogenesis (New York) (01-01-2017)“…Polymorphisms in microRNA (miRNA) binding sites may affect miRNA/target gene interaction, resulting in differential mRNA/protein expression and susceptibility…”
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Synthesis and Initial in Vitro Evaluations of Novel Antioxidant Aroylhydrazone Iron Chelators with Increased Stability against Plasma Hydrolysis
Published in Chemical research in toxicology (21-03-2011)“…Oxidative stress is known to contribute to a number of cardiovascular pathologies. Free intracellular iron ions participate in the Fenton reaction and…”
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Expression quantitative trait loci in ABC transporters are associated with survival in 5-FU treated colorectal cancer patients
Published in Mutagenesis (11-07-2020)“…The chemotherapeutic efficacy in colorectal cancer (CRC) is limited due to the inter-individual variability in drug response and the development of tumour…”
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Abstract 3411: Role of mucin gene variations in microRNA binding sites in modulating colorectal cancer susceptibility and clinical outcomes
Published in Cancer research (Chicago, Ill.) (15-07-2016)“…Abstract Mucins, high molecular weight glycoproteins predominantly expressed at the epithelial surface of tissues, provide protection for colon surface under…”
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Comparison of Clinically Used and Experimental Iron Chelators for Protection against Oxidative Stress-Induced Cellular Injury
Published in Chemical research in toxicology (21-06-2010)“…Iron imbalance plays an important role in oxidative stress associated with numerous pathological conditions. Therefore, iron chelation may be an effective…”
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