Search Results - "Bendor, Jacob"

The Function of α-Synuclein by Bendor, Jacob T., Logan, Todd P., Edwards, Robert H.

“…Human genetics has indicated a causal role for the protein α-synuclein in the pathogenesis of familial Parkinson’s disease (PD), and the aggregation of…”
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Acetylcholine receptor based chemogenetics engineered for neuronal inhibition and seizure control assessed in mice by Nguyen, Quynh-Anh, Klein, Peter M., Xie, Cheng, Benthall, Katelyn N., Iafrati, Jillian, Homidan, Jesslyn, Bendor, Jacob T., Dudok, Barna, Farrell, Jordan S., Gschwind, Tilo, Porter, Charlotte L., Keravala, Annahita, Dodson, G. Steven, Soltesz, Ivan

“…Epilepsy is a prevalent disorder involving neuronal network hyperexcitability, yet existing therapeutic strategies often fail to provide optimal patient…”
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FGF acts as a co-transmitter through adenosine A2A receptor to regulate synaptic plasticity by Flajolet, Marc, Wang, Zhongfeng, Futter, Marie, Shen, Weixing, Nuangchamnong, Nina, Bendor, Jacob, Wallach, Iwona, Nairn, Angus C, Surmeier, D James, Greengard, Paul

“…Adenosine receptor A 2A R is known to antagonize dopaminergic signaling in the striatum and its malfunctions have been implicated in various striatum-related…”
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A mouse model of autism implicates endosome pH in the regulation of presynaptic calcium entry by Ullman, Julie C., Yang, Jing, Sullivan, Michael, Bendor, Jacob, Levy, Jonathan, Pham, Ellen, Silm, Katlin, Seifikar, Helia, Sohal, Vikaas S., Nicoll, Roger A., Edwards, Robert H.

“…Psychoactive compounds such as chloroquine and amphetamine act by dissipating the pH gradient across intracellular membranes, but the physiological mechanisms…”
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Norbin Is an Endogenous Regulator of Metabotropic Glutamate Receptor 5 Signaling by Wang, Hong, Westin, Linda, Nong, Yi, Birnbaum, Shari, Bendor, Jacob, Brismar, Hjalmar, Nestler, Eric, Aperia, Anita, Flajolet, Marc, Greengard, Paul

“…Metabotropic glutamate receptor 5 (mGluR5) is highly expressed in the mammalian central nervous system (CNS). It is involved in multiple physiological…”
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Mu opioid receptor and orexin/hypocretin mRNA levels in the lateral hypothalamus and striatum are enhanced by morphine withdrawal by Zhou, Yan, Bendor, Jacob, Hofmann, Lauren, Randesi, Matthew, Ho, Ann, Kreek, Mary Jeanne

“…In this study, we investigated the effects of acute morphine administration, chronic intermittent escalating-dose morphine administration and spontaneous…”
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Cerebellar vermis involvement in cocaine-related behaviors by ANDERSON, Carl M, MAAS, Luis C, KAUFMAN, Marc J, FREDERICK, Blaise De B, BENDOR, Jacob T, SPENCER, Thomas J, LIVNI, Eli, LUKAS, Scott E, FISCHMAN, Alan J, MADRAS, Bertha K, RENSHAW, Perry F

“…Although the cerebellum is increasingly being viewed as a brain area involved in cognition, it typically is excluded from circuitry considered to mediate…”
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Loss of α-Synuclein Does Not Affect Mitochondrial Bioenergetics in Rodent Neurons by Pathak, Divya, Berthet, Amandine, Bendor, Jacob T, Yu, Katharine, Sellnow, Rhyomi C, Orr, Adam L, Nguyen, Mai K, Edwards, Robert H, Manfredsson, Fredric P, Nakamura, Ken

“…Increased α-synuclein (αsyn) and mitochondrial dysfunction play central roles in the pathogenesis of Parkinson's disease (PD), and lowering αsyn is under…”
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AGAP1/AP-3-dependent endocytic recycling of M5 muscarinic receptors promotes dopamine release by Bendor, Jacob, Lizardi-Ortiz, José E, Westphalen, Robert I, Brandstetter, Markus, Hemmings Jr, Hugh C, Sulzer, David, Flajolet, Marc, Greengard, Paul

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α-Synuclein promotes dilation of the exocytotic fusion pore by Logan, Todd, Bendor, Jacob, Toupin, Chantal, Thorn, Kurt, Edwards, Robert H

“…The authors used knockout mice to demonstrate the normal function of the protein α-synuclein, which has a central role in Parkinson's and other…”
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Dopamine transporter (DAT) inhibitors alleviate specific parkinsonian deficits in monkeys: association with DAT occupancy in vivo by Madras, Bertha K, Fahey, Michele A, Goulet, Martin, Lin, Zhicheng, Bendor, Jacob, Goodrich, Claudia, Meltzer, Peter C, Elmaleh, David R, Livni, Eli, Bonab, Ali A, Fischman, Alan J

“…Viable dopamine neurons in Parkinson's disease express the dopamine transporter (DAT) and release dopamine (DA). We postulated that potent DAT inhibitors, with…”
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FGF acts as a co-transmitter through adenosine A(2A) receptor to regulate synaptic plasticity by Flajolet, Marc, Wang, Zhongfeng, Futter, Marie, Shen, Weixing, Nuangchamnong, Nina, Bendor, Jacob, Wallach, Iwona, Nairn, Angus C, Surmeier, D James, Greengard, Paul

“…Abnormalities of striatal function have been implicated in several major neurological and psychiatric disorders, including Parkinson's disease, schizophrenia…”
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[alpha]-Synuclein promotes dilation of the exocytotic fusion pore by Logan, Todd, Bendor, Jacob, Toupin, Chantal, Thorn, Kurt, Edwards, Robert H

“…The protein α-synuclein has a central role in the pathogenesis of Parkinson's disease. Like that of other proteins that accumulate in neurodegenerative…”
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The Function of ?-Synuclein by Bendor, Jacob T, Logan, Todd P, Edwards, Robert H

“…Human genetics has indicated a causal role for the protein ?-synuclein in the pathogenesis of familial Parkinson's disease (PD), and the aggregation of…”
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AGAP1/AP-3-dependent endocytic recycling of M 5 muscarinic receptors promotes dopamine release by Bendor, Jacob, Lizardi-Ortiz, José E, Westphalen, Robert I, Brandstetter, Markus, Hemmings, Hugh C, Sulzer, David, Flajolet, Marc, Greengard, Paul

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Cerebellar Vermis Involvement in Cocaine-Related Behaviors by Anderson, Carl M, Maas, Luis C, Frederick, Blaise deB, Bendor, Jacob T, Spencer, Thomas J, Livni, Eli, Lukas, Scott E, Fischman, Alan J, Madras, Bertha K, Renshaw, Perry F, Kaufman, Marc J

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AGAP1/AP‐3‐dependent endocytic recycling of M5 muscarinic receptors promotes dopamine release by Bendor, Jacob, Lizardi‐Ortiz, José E, Westphalen, Robert I, Brandstetter, Markus, Hemmings, Hugh C, Sulzer, David, Flajolet, Marc, Greengard, Paul

“…Of the five mammalian muscarinic acetylcholine (ACh) receptors, M 5 is the only subtype expressed in midbrain dopaminergic neurons, where it functions to…”
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FGF acts as a co-transmitter through adenosine A sub(2A) receptor to regulate synaptic plasticity by Flajolet, Marc, Wang, Zhongfeng, Futter, Marie, Shen, Weixing, Nuangchamnong, Nina, Bendor, Jacob, Wallach, Iwona, Nairn, Angus C, Surmeier, D James, Greengard, Paul

“…Abnormalities of striatal function have been implicated in several major neurological and psychiatric disorders, including Parkinson's disease, schizophrenia…”
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FGF acts as a co-transmitter through Adenosine A2A receptor to regulate morphological and physiological synaptic plasticity by Flajolet, Marc, Wang, Zhongfeng, Futter, Marie, Shen, Weixing, Nuangchamnong, Nina, Bendor, Jacob, Palaszewski, Iwona, Nairn, Angus C., Surmeier, D. James, Greengard, Paul

“…Abnormalities of striatal function have been implicated in several major neurological and psychiatric disorders, including Parkinson's disease, schizophrenia,…”
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Immediate withdrawal from chronic “binge” cocaine administration increases μ-opioid receptor mRNA levels in rat frontal cortex by Bailey, Alexis, Yuferov, Vadim, Bendor, Jacob, Schlussman, Stefan D., Zhou, Yan, Ho, Ann, Kreek, Mary Jeanne

“…An increase in preprodynorphin (ppdyn) mRNA was detected in the caudate putamen of chronically cocaine-treated and 3-h withdrawn rats. An increase in μ-opioid…”
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