Search Results - "Bendlin, Barbara B."

Biomarkers for Alzheimer’s disease—preparing for a new era of disease-modifying therapies by Zetterberg, Henrik, Bendlin, Barbara B.

“…Clinical trial results presented in 2019 suggest that antibody-based removal of cerebral amyloid β (Aβ) plaques may possibly clear tau tangles and modestly…”
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Gut microbiome alterations in Alzheimer’s disease by Vogt, Nicholas M., Kerby, Robert L., Dill-McFarland, Kimberly A., Harding, Sandra J., Merluzzi, Andrew P., Johnson, Sterling C., Carlsson, Cynthia M., Asthana, Sanjay, Zetterberg, Henrik, Blennow, Kaj, Bendlin, Barbara B., Rey, Federico E.

“…Alzheimer’s disease (AD) is the most common form of dementia. However, the etiopathogenesis of this devastating disease is not fully understood. Recent studies…”
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The gut microbiota-derived metabolite trimethylamine N-oxide is elevated in Alzheimer's disease by Vogt, Nicholas M, Romano, Kymberleigh A, Darst, Burcu F, Engelman, Corinne D, Johnson, Sterling C, Carlsson, Cynthia M, Asthana, Sanjay, Blennow, Kaj, Zetterberg, Henrik, Bendlin, Barbara B, Rey, Federico E

“…Trimethylamine N-oxide (TMAO), a small molecule produced by the metaorganismal metabolism of dietary choline, has been implicated in human disease…”
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Microstructural white matter alterations in preclinical Alzheimer's disease detected using free water elimination diffusion tensor imaging by Hoy, Andrew R, Ly, Martina, Carlsson, Cynthia M, Okonkwo, Ozioma C, Zetterberg, Henrik, Blennow, Kaj, Sager, Mark A, Asthana, Sanjay, Johnson, Sterling C, Alexander, Andrew L, Bendlin, Barbara B

“…Brain changes associated with Alzheimer's disease (AD) begin decades before disease diagnosis. While β-amyloid plaques and neurofibrillary tangles are defining…”
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Cortical Microstructural Alterations in Mild Cognitive Impairment and Alzheimer’s Disease Dementia by Vogt, Nicholas M, Hunt, Jack F, Adluru, Nagesh, Dean, Douglas C, Johnson, Sterling C, Asthana, Sanjay, Yu, John-Paul J, Alexander, Andrew L, Bendlin, Barbara B

“…Abstract In Alzheimer’s disease (AD), neurodegenerative processes are ongoing for years prior to the time that cortical atrophy can be reliably detected using…”
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An examination of a novel multipanel of CSF biomarkers in the Alzheimer's disease clinical and pathological continuum by Van Hulle, Carol, Jonaitis, Erin M., Betthauser, Tobey J., Batrla, Richard, Wild, Norbert, Kollmorgen, Gwendlyn, Andreasson, Ulf, Okonkwo, Ozioma, Bendlin, Barbara B., Asthana, Sanjay, Carlsson, Cynthia M., Johnson, Sterling C., Zetterberg, Henrik, Blennow, Kaj

“…Introduction This study examines the utility of a multipanel of cerebrospinal fluid (CSF) biomarkers complementing Alzheimer's disease (AD) biomarkers in a…”
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Optimizing the intrinsic parallel diffusivity in NODDI: An extensive empirical evaluation by Guerrero, Jose M, Adluru, Nagesh, Bendlin, Barbara B, Goldsmith, H Hill, Schaefer, Stacey M, Davidson, Richard J, Kecskemeti, Steven R, Zhang, Hui, Alexander, Andrew L

“…NODDI is widely used in parameterizing microstructural brain properties. The model includes three signal compartments: intracellular, extracellular, and free…”
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Alterations of Myelin Content in Parkinson's Disease: A Cross-Sectional Neuroimaging Study by Dean, 3rd, Douglas C, Sojkova, Jitka, Hurley, Samuel, Kecskemeti, Steven, Okonkwo, Ozioma, Bendlin, Barbara B, Theisen, Frances, Johnson, Sterling C, Alexander, Andrew L, Gallagher, Catherine L

“…Alterations to myelin may be a core pathological feature of neurodegenerative diseases. Although white matter microstructural differences have been described…”
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Insulin resistance predicts brain amyloid deposition in late middle-aged adults by Willette, Auriel A, Johnson, Sterling C, Birdsill, Alex C, Sager, Mark A, Christian, Bradley, Baker, Laura D, Craft, Suzanne, Oh, Jennifer, Statz, Eric, Hermann, Bruce P, Jonaitis, Erin M, Koscik, Rebecca L, La Rue, Asenath, Asthana, Sanjay, Bendlin, Barbara B

“…Abstract Background Insulin resistance (IR) increases Alzheimer's disease (AD) risk. IR is related to greater amyloid burden post-mortem and increased…”
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Insulin Resistance, Brain Atrophy, and Cognitive Performance in Late Middle―Aged Adults by WILLETTE, Auriel A, GUOFAN XU, JOHNSON, Sterling C, BIRDSILL, Alex C, JONAITIS, Erin M, SAGER, Mark A, HERMANN, Bruce P, LA RUE, Asenath, ASTHANA, Sanjay, BENDLIN, Barbara B

“…Insulin resistance dysregulates glucose uptake and other functions in brain areas affected by Alzheimer disease. Insulin resistance may play a role in…”
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Physical activity attenuates age-related biomarker alterations in preclinical AD by Okonkwo, Ozioma C, Schultz, Stephanie A, Oh, Jennifer M, Larson, Jordan, Edwards, Dorothy, Cook, Dane, Koscik, Rebecca, Gallagher, Catherine L, Dowling, N.M, Carlsson, Cynthia M, Bendlin, Barbara B, LaRue, Asenath, Rowley, Howard A, Christian, Brad T, Asthana, Sanjay, Hermann, Bruce P, Johnson, Sterling C, Sager, Mark A

“…OBJECTIVE:To examine whether engagement in physical activity might favorably alter the age-dependent evolution of Alzheimer disease (AD)-related brain and…”
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Cerebrospinal Fluid and Plasma Levels of Inflammation Differentially Relate to CNS Markers of Alzheimer's Disease Pathology and Neuronal Damage by Bettcher, Brianne M, Johnson, Sterling C, Fitch, Ryan, Casaletto, Kaitlin B, Heffernan, Kate S, Asthana, Sanjay, Zetterberg, Henrik, Blennow, Kaj, Carlsson, Cynthia M, Neuhaus, John, Bendlin, Barbara B, Kramer, Joel H

“…Inflammatory markers have been shown to predict neurocognitive outcomes in aging adults; however, the degree to which peripheral markers mirror the central…”
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Insights from the IronTract challenge: Optimal methods for mapping brain pathways from multi-shell diffusion MRI by Maffei, Chiara, Girard, Gabriel, Schilling, Kurt G., Aydogan, Dogu Baran, Adluru, Nagesh, Zhylka, Andrey, Wu, Ye, Mancini, Matteo, Hamamci, Andac, Sarica, Alessia, Teillac, Achille, Baete, Steven H., Karimi, Davood, Yeh, Fang-Cheng, Yildiz, Mert E., Gholipour, Ali, Bihan-Poudec, Yann, Hiba, Bassem, Quattrone, Andrea, Quattrone, Aldo, Boshkovski, Tommy, Stikov, Nikola, Yap, Pew-Thian, de Luca, Alberto, Pluim, Josien, Leemans, Alexander, Prabhakaran, Vivek, Bendlin, Barbara B., Alexander, Andrew L., Landman, Bennett A., Canales-Rodríguez, Erick J., Barakovic, Muhamed, Rafael-Patino, Jonathan, Yu, Thomas, Rensonnet, Gaëtan, Schiavi, Simona, Daducci, Alessandro, Pizzolato, Marco, Fischi-Gomez, Elda, Thiran, Jean-Philippe, Dai, George, Grisot, Giorgia, Lazovski, Nikola, Puch, Santi, Ramos, Marc, Rodrigues, Paulo, Prčkovska, Vesna, Jones, Robert, Lehman, Julia, Haber, Suzanne N., Yendiki, Anastasia

“…Limitations in the accuracy of brain pathways reconstructed by diffusion MRI (dMRI) tractography have received considerable attention. While the technical…”
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The iterative process of fluid biomarker development and validation in Alzheimer's disease by Bendlin, Barbara B., Zetterberg, Henrik

“…Alzheimer's disease (AD) is a progressive neurodegenerative dementia for which disease-modifying treatments, likely to be the most effective in early disease…”
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Multi-resolution statistical analysis of brain connectivity graphs in preclinical Alzheimer's disease by Kim, Won Hwa, Adluru, Nagesh, Chung, Moo K., Okonkwo, Ozioma C., Johnson, Sterling C., B. Bendlin, Barbara, Singh, Vikas

“…There is significant interest, both from basic and applied research perspectives, in understanding how structural/functional connectivity changes can explain…”
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The Wisconsin Registry for Alzheimer's Prevention: A review of findings and current directions by Johnson, Sterling C., Koscik, Rebecca L., Jonaitis, Erin M., Clark, Lindsay R., Mueller, Kimberly D., Berman, Sara E., Bendlin, Barbara B., Engelman, Corinne D., Okonkwo, Ozioma C., Hogan, Kirk J., Asthana, Sanjay, Carlsson, Cynthia M., Hermann, Bruce P., Sager, Mark A.

“…The Wisconsin Registry for Alzheimer's Prevention is a longitudinal observational cohort study enriched with persons with a parental history (PH) of probable…”
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Longitudinal white matter microstructural change in Parkinson's disease by Pozorski, Vincent, Oh, Jennifer M., Adluru, Nagesh, Merluzzi, Andrew P., Theisen, Frances, Okonkwo, Ozioma, Barzgari, Amy, Krislov, Stephanie, Sojkova, Jitka, Bendlin, Barbara B., Johnson, Sterling C., Alexander, Andrew L., Gallagher, Catherine L.

“…Postmortem studies of Parkinson's disease (PD) suggest that Lewy body pathology accumulates in a predictable topographical sequence, beginning in the olfactory…”
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Author Correction: Whole-body metabolic modelling reveals microbiome and genomic interactions on reduced urine formate levels in Alzheimer’s disease by Martinelli, Filippo, Heinken, Almut, Henning, Ann-Kristin, Ulmer, Maria A., Hensen, Tim, González, Antonio, Arnold, Matthias, Asthana, Sanjay, Budde, Kathrin, Engelman, Corinne D., Estaki, Mehrbod, Grabe, Hans-Jörgen, Heston, Margo B., Johnson, Sterling, Kastenmüller, Gabi, Martino, Cameron, McDonald, Daniel, Rey, Federico E., Kilimann, Ingo, Peters, Olive, Wang, Xiao, Spruth, Eike Jakob, Schneider, Anja, Fliessbach, Klaus, Wiltfang, Jens, Hansen, Niels, WenzelGlanz, Buerger, Katharina, Janowitz, Daniel, Laske, Christoph, Munk, Matthias H., Spottke, Annika, Roy, Nina, Nauck, Matthias, Teipel, Stefan, Knight, Rob, Kaddurah-Daouk, Rima F., Bendlin, Barbara B., Hertel, Johannes, Thiele, Ines

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Measuring longitudinal cognition: Individual tests versus composites by Jonaitis, Erin M., Koscik, Rebecca L., Clark, Lindsay R., Ma, Yue, Betthauser, Tobey J., Berman, Sara E., Allison, Samantha L., Mueller, Kimberly D., Hermann, Bruce P., Van Hulle, Carol A., Christian, Bradley T., Bendlin, Barbara B., Blennow, Kaj, Zetterberg, Henrik, Carlsson, Cynthia M., Asthana, Sanjay, Johnson, Sterling C.

“…Longitudinal cohort studies of cognitive aging must confront several sources of within-person variability in scores. In this article, we compare several…”
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Longitudinal diffusion tensor imaging and neuropsychological correlates in traumatic brain injury patients by Farbota, Kimberly D, Bendlin, Barbara B, Alexander, Andrew L, Rowley, Howard A, Dempsey, Robert J, Johnson, Sterling C

“…Traumatic brain injury (TBI) often involves focal cortical injury and white matter (WM) damage that can be measured shortly after injury. Additionally, slowly…”
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