Search Results - "Bencze, László Csaba"
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A Peptidomimetic Antibiotic Interacts with the Periplasmic Domain of LptD from Pseudomonas aeruginosa
Published in ACS chemical biology (16-03-2018)“…The outer membrane (OM) in Gram-negative bacteria is an asymmetric bilayer with mostly lipopolysaccharide (LPS) molecules in the outer leaflet. During OM…”
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2
Engineered, Scalable Production of Optically Pure l‑Phenylalanines Using Phenylalanine Ammonia-Lyase from Arabidopsis thaliana
Published in Journal of organic chemistry (20-01-2023)“…An efficient preparative-scale synthetic procedure of l-phenylalanine derivatives has been developed using mutant variants of phenylalanine ammonia-lyase from…”
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3
Toolbox for the structure-guided evolution of ferulic acid decarboxylase (FDC)
Published in Scientific reports (01-03-2022)“…The interest towards ferulic acid decarboxylase (FDC), piqued by the enzyme’s unique 1,3-dipolar cycloaddition mechanism and its atypic prFMN cofactor,…”
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4
Towards a general approach for tailoring the hydrophobic binding site of phenylalanine ammonia-lyases
Published in Scientific reports (23-06-2022)“…Unnatural substituted amino acids play an important role as chiral building blocks, especially for pharmaceutical industry, where the synthesis of chiral…”
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5
Efficient and Stable Magnetic Chitosan-Lipase B from Candida Antarctica Bioconjugates in the Enzymatic Kinetic Resolution of Racemic Heteroarylethanols
Published in Molecules (Basel, Switzerland) (15-01-2020)“…Lipase B from immobilized by covalent binding on sebacoyl-activated chitosan-coated magnetic nanoparticles proved to be an efficient biocatalyst (49.2-50%…”
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6
Efficient Biodiesel Production Catalyzed by Nanobioconjugate of Lipase from Pseudomonas fluorescens
Published in Molecules (Basel, Switzerland) (03-02-2020)“…The Amano lipase from (L-AK) was covalently immobilized on various carbon nanomaterials (functionalized single-walled carbon nanotubes and graphene oxide) and…”
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7
Heterocycles 48. Synthesis, Characterization and Biological Evaluation of Imidazo[2,1- b ][1,3,4]Thiadiazole Derivatives as Anti-Inflammatory Agents
Published in Molecules (Basel, Switzerland) (21-09-2018)“…Non-steroidal anti-inflammatory drugs (NSAIDs) are an important pharmacological class of drugs used for the treatment of inflammatory diseases. They are also…”
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8
Green Process for the Enzymatic Synthesis of Aroma Compounds Mediated by Lipases Entrapped in Tailored Sol–Gel Matrices
Published in ACS sustainable chemistry & engineering (19-04-2021)“…We report a simple enzymatic procedure for the synthesis of short-chained flavor esters by direct esterification of natural acids with short-chain primary…”
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9
Exploring the substrate scope of ferulic acid decarboxylase (FDC1) from Saccharomyces cerevisiae
Published in Scientific reports (24-01-2019)“…Ferulic acid decarboxylase from Saccharomyces cerevisiae ( Sc FDC1) was described to possess a novel, prenylated flavin mononucleotide cofactor (prFMN)…”
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10
Solvent-Free Biocatalytic Synthesis of 2,5-bis-(Hydroxymethyl)Furan Fatty Acid Diesters from Renewable Resources
Published in ACS sustainable chemistry & engineering (27-01-2020)“…Fatty acid diesters of 2,5-bis-(hydroxymethyl)furan (BHMF), promising candidates as sustainable bioadditives for increasing the cetane number of biodiesel…”
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11
Saturation Mutagenesis for Phenylalanine Ammonia Lyases of Enhanced Catalytic Properties
Published in Biomolecules (Basel, Switzerland) (30-05-2020)“…Phenylalanine ammonia-lyases (PALs) are attractive biocatalysts for the stereoselective synthesis of non-natural phenylalanines. The rational design of PALs…”
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12
Heterocycles 38. Biocatalytic Synthesis of New Heterocyclic Mannich Bases and Derivatives
Published in Molecules (Basel, Switzerland) (06-07-2015)“…This paper describes the biocatalytic synthesis of new Mannich bases containing various heterocyclic rings (thiazole, furane, thiophene, pyridine) by applying…”
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Heterocycles 36. Single-Walled Carbon Nanotubes-Bound N,N-Diethyl Ethanolamine as Mild and Efficient Racemisation Agent in the Enzymatic DKR of 2-Arylthiazol-4-yl-alanines
Published in Molecules (Basel, Switzerland) (25-12-2015)“…In this paper we describe the chemoenzymatic synthesis of enantiopure l-2-arylthiazol-4-yl alanines starting from their racemic N-acetyl derivatives; by…”
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14
Chemoenzymatic Preparation of 1-Heteroarylethanamines of Low Solubility
Published in European journal of organic chemistry (01-06-2012)“…Both enantiomers of biologically and pharmaceutically interesting benzofuran‐, benzothiophen‐, and phenylfuran‐based 1‐heteroarylethanamines were prepared at…”
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15
2-Amino-3-(5-phenylfuran-2-yl)propionic Acids and 5-Phenylfuran-2-ylacrylic Acids are Novel Substrates of Phenylalanine Ammonia-Lyase
Published in Heterocycles (01-03-2011)Get full text
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16
Phenylalanine ammonia-lyases: combining protein engineering and natural diversity
Published in Applied microbiology and biotechnology (01-02-2023)“…In this study, rational design and saturation mutagenesis efforts for engineering phenylalanine ammonia-lyase from Petroselinum crispum ( Pc PAL) provided…”
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17
Chemoenzymatic synthesis of highly enantiomerically enriched secondary alcohols with a thiazolic core
Published in Tetrahedron: asymmetry (15-04-2012)“…Stereoselective preparative enzymatic acylation and hydrolysis/methanolysis of various C-substituted rac-thiazol-2-yl-methanols were achieved for the…”
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18
Ancestral l-amino acid oxidase: from substrate scope exploration to phenylalanine ammonia-lyase assay
Published in Journal of biotechnology (20-11-2023)“…In this study we assessed the applicability of the recently reported ancestral l-amino acid oxidase (AncLAAO), for the development of an enzyme-coupled…”
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19
A novel phenylalanine ammonia-lyase from Pseudozyma antarctica for stereoselective biotransformations of unnatural amino acids
Published in Catalysis today (15-04-2021)“…[Display omitted] •Novel phenylalanine ammonia-lyase for the production of unnatural amino acids.•Superior turnover numbers compared to known phenylalanine…”
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20
Immobilization of d-amino acid dehydrogenase from Ureibacillus thermosphaericus
Published in Process biochemistry (1991) (01-05-2024)“…Several procedures were tested for the immobilization of the artificial d-selective amino acid dehydrogenase from Ureibacillus thermosphaericus (UtDAADH) and…”
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