Search Results - "Bencivenni, Serena"

Inhibition of A2A Adenosine Receptor Signaling in Cancer Cells Proliferation by the Novel Antagonist TP455 by Gessi, Stefania, Bencivenni, Serena, Battistello, Enrica, Vincenzi, Fabrizio, Colotta, Vittoria, Catarzi, Daniela, Varano, Flavia, Merighi, Stefania, Borea, Pier Andrea, Varani, Katia

“…Several evidences indicate that the ubiquitous nucleoside adenosine, acting through A 1 , A 2A , A 2B , and A 3 receptor (AR) subtypes, plays crucial roles in…”
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A 2B adenosine receptors stimulate IL-6 production in primary murine microglia through p38 MAPK kinase pathway by Merighi, Stefania, Bencivenni, Serena, Vincenzi, Fabrizio, Varani, Katia, Borea, Pier Andrea, Gessi, Stefania

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The activation of μ‐opioid receptor potentiates LPS‐induced NF‐kB promoting an inflammatory phenotype in microglia by Gessi, Stefania, Borea, Pier Andrea, Bencivenni, Serena, Fazzi, Debora, Varani, Katia, Merighi, Stefania

“…Increased production of proinflammatory cytokines has a prominent role in tolerance to opioids. The objectives of this study were to examine whether μ‐opioid…”
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A2B adenosine receptors stimulate IL-6 production in primary murine microglia through p38 MAPK kinase pathway by Merighi, Stefania, Bencivenni, Serena, Vincenzi, Fabrizio, Varani, Katia, Borea, Pier Andrea, Gessi, Stefania

“…[Display omitted] The hallmark of neuroinflammation is the activation of microglia, the immunocompetent cells of the CNS, releasing a number of proinflammatory…”
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A2a and a2b adenosine receptors affect HIF-1α signaling in activated primary microglial cells by Merighi, Stefania, Borea, Pier Andrea, Stefanelli, Angela, Bencivenni, Serena, Castillo, Carlos Alberto, Varani, Katia, Gessi, Stefania

“…Microglia are central nervous system (CNS)‐resident immune cells, that play a crucial role in neuroinflammation. Hypoxia‐inducible factor‐1 (HIF‐1), the main…”
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Pulsed electromagnetic field and relief of hypoxia‐induced neuronal cell death: The signaling pathway by Gessi, Stefania, Merighi, Stefania, Bencivenni, Serena, Battistello, Enrica, Vincenzi, Fabrizio, Setti, Stefania, Cadossi, Matteo, Borea, Pier Andrea, Cadossi, Ruggero, Varani, Katia

“…Low‐energy low‐frequency pulsed electromagnetic fields (PEMFs) exert several protective effects, such as the regulation of kinases, transcription factors as…”
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Signaling pathways involved in anti-inflammatory effects of Pulsed Electromagnetic Field in microglial cells by Merighi, Stefania, Gessi, Stefania, Bencivenni, Serena, Battistello, Enrica, Vincenzi, Fabrizio, Setti, Stefania, Cadossi, Matteo, Borea, Pier Andrea, Cadossi, Ruggero, Varani, Katia

“…[Display omitted] •PEMFs block neuroinflammation in microglial cells.•PEMFs reduce the production of pro-inflammatory cytokines from activated microglial…”
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Synthesis, molecular modeling and SAR study of novel pyrazolo[5,1-f][1,6]naphthyridines as CB2 receptor antagonists/inverse agonists by Dore, Antonio, Asproni, Battistina, Scampuddu, Alessia, Gessi, Stefania, Murineddu, Gabriele, Cichero, Elena, Fossa, Paola, Merighi, Stefania, Bencivenni, Serena, Pinna, Gérard A.

“…[Display omitted] •Novel pyrazolo[5,1-f][1,6]naphthyridines were synthesized.•Cannabinoid receptor binding at CB1/CB2 and functional assays were…”
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A2a and a2b adenosine receptors affect HIF-1[alpha] signaling in activated primary microglial cells by Merighi, Stefania, Borea, Pier Andrea, Stefanelli, Angela, Bencivenni, Serena, Castillo, Carlos Alberto, Varani, Katia, Gessi, Stefania

“…Microglia are central nervous system (CNS)-resident immune cells, that play a crucial role in neuroinflammation. Hypoxia-inducible factor-1 (HIF-1), the main…”
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A sub(2a) and a sub(2b) adenosine receptors affect HIF-1 alpha signaling in activated primary microglial cells by Merighi, Stefania, Borea, Pier Andrea, Stefanelli, Angela, Bencivenni, Serena, Castillo, Carlos Alberto, Varani, Katia, Gessi, Stefania

“…Microglia are central nervous system (CNS)-resident immune cells, that play a crucial role in neuroinflammation. Hypoxia-inducible factor-1 (HIF-1), the main…”
Get full text

A 2a and a 2b adenosine receptors affect HIF-1α signaling in activated primary microglial cells by Merighi, Stefania, Borea, Pier Andrea, Stefanelli, Angela, Bencivenni, Serena, Castillo, Carlos Alberto, Varani, Katia, Gessi, Stefania

“…Microglia are central nervous system (CNS)-resident immune cells, that play a crucial role in neuroinflammation. Hypoxia-inducible factor-1 (HIF-1), the main…”
Get full text

Synthesis, molecular modeling and SAR study of novel pyrazolo[5,1-f][1,6]naphthyridines as CB 2 receptor antagonists/inverse agonists by Dore, Antonio, Asproni, Battistina, Scampuddu, Alessia, Gessi, Stefania, Murineddu, Gabriele, Cichero, Elena, Fossa, Paola, Merighi, Stefania, Bencivenni, Serena, Pinna, Gérard A

“…Pyrazolo[5,1-f][1,6]naphthyridine-carboxamide derivatives were synthesized and evaluated for the affinity at CB and CB receptors. Based on the AgOTf and…”
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Synthesis, Pharmacological Evaluation, and Docking Studies of Novel Pyridazinone‐Based Cannabinoid Receptor Type 2 Ligands by Ragusa, Giulio, Bencivenni, Serena, Morales, Paula, Callaway, Tyra, Hurst, Dow P., Asproni, Battistina, Merighi, Stefania, Loriga, Giovanni, Pinna, Gerard A., Reggio, Patricia H., Gessi, Stefania, Murineddu, Gabriele

“…In recent years, cannabinoid type 2 receptors (CB2R) have emerged as promising therapeutic targets in a wide variety of diseases. Selective ligands of CB2R are…”
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Inhibition of A 2A Adenosine Receptor Signaling in Cancer Cells Proliferation by the Novel Antagonist TP455 by Gessi, Stefania, Bencivenni, Serena, Battistello, Enrica, Vincenzi, Fabrizio, Colotta, Vittoria, Catarzi, Daniela, Varano, Flavia, Merighi, Stefania, Borea, Pier Andrea, Varani, Katia

“…Several evidences indicate that the ubiquitous nucleoside adenosine, acting through A , A , A , and A receptor (AR) subtypes, plays crucial roles in tumor…”
Get full text

A 2B adenosine receptors stimulate IL-6 production in primary murine microglia through p38 MAPK kinase pathway by Merighi, Stefania, Bencivenni, Serena, Vincenzi, Fabrizio, Varani, Katia, Borea, Pier Andrea, Gessi, Stefania

“…The hallmark of neuroinflammation is the activation of microglia, the immunocompetent cells of the CNS, releasing a number of proinflammatory mediators…”
Get full text