Search Results - "Benanti, Jennifer A."

Repression of essential cell cycle genes increases cellular fitness by Conti, Michelle M, Ghizzoni, Julie M, Gil-Bona, Ana, Wang, Wen, Costanzo, Michael, Li, Rui, Flynn, Mackenzie J, Zhu, Lihua Julie, Myers, Chad L, Boone, Charles, Andrews, Brenda J, Benanti, Jennifer A

“…A network of transcription factors (TFs) coordinates transcription with cell cycle events in eukaryotes. Most TFs in the network are phosphorylated by…”
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Coordination of cell growth and division by the ubiquitin–proteasome system by Benanti, Jennifer A.

“…► Coupling of growth and the cell cycle is important for accurate cell proliferation. ► The UPS targets cell cycle and metabolic regulatory proteins for…”
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Phosphosite Scanning reveals a complex phosphorylation code underlying CDK-dependent activation of Hcm1 by Conti, Michelle M., Li, Rui, Narváez Ramos, Michelle A., Zhu, Lihua Julie, Fazzio, Thomas G., Benanti, Jennifer A.

“…Ordered cell cycle progression is coordinated by cyclin dependent kinases (CDKs). CDKs often phosphorylate substrates at multiple sites clustered within…”
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The coordinate actions of calcineurin and Hog1 mediate the stress response through multiple nodes of the cell cycle network by Leech, Cassandra M, Flynn, Mackenzie J, Arsenault, Heather E, Ou, Jianhong, Liu, Haibo, Zhu, Lihua Julie, Benanti, Jennifer A

“…Upon exposure to environmental stressors, cells transiently arrest the cell cycle while they adapt and restore homeostasis. A challenge for all cells is to…”
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Levels of Ycg1 Limit Condensin Function during the Cell Cycle by Doughty, Tyler W, Arsenault, Heather E, Benanti, Jennifer A

“…During mitosis chromosomes are condensed to facilitate their segregation, through a process mediated by the condensin complex. Although several factors that…”
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An order-to-disorder structural switch activates the FoxM1 transcription factor by Marceau, Aimee H, Brison, Caileen M, Nerli, Santrupti, Arsenault, Heather E, McShan, Andrew C, Chen, Eefei, Lee, Hsiau-Wei, Benanti, Jennifer A, Sgourakis, Nikolaos G, Rubin, Seth M

“…Intrinsically disordered transcription factor transactivation domains (TADs) function through structural plasticity, adopting ordered conformations when bound…”
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Hcm1 integrates signals from Cdk1 and calcineurin to control cell proliferation by Arsenault, Heather E, Roy, Jagoree, Mapa, Claudine E, Cyert, Martha S, Benanti, Jennifer A

“…Cyclin-dependent kinase (Cdk1) orchestrates progression through the cell cycle by coordinating the activities of cell-cycle regulators. Although phosphatases…”
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F-box protein specificity for g1 cyclins is dictated by subcellular localization by Landry, Benjamin D, Doyle, John P, Toczyski, David P, Benanti, Jennifer A

“…Levels of G1 cyclins fluctuate in response to environmental cues and couple mitotic signaling to cell cycle entry. The G1 cyclin Cln3 is a key regulator of…”
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Ubc1 turnover contributes to the spindle assembly checkpoint in Saccharomyces cerevisiae by Arsenault, Heather E, Ghizzoni, Julie M, Leech, Cassandra M, Diers, Anne R, Gesta, Stephane, Vishnudas, Vivek K, Narain, Niven R, Sarangarajan, Rangaprasad, Benanti, Jennifer A

“…Abstract The spindle assembly checkpoint protects the integrity of the genome by ensuring that chromosomes are properly attached to the mitotic spindle before…”
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Rad53 Downregulates Mitotic Gene Transcription by Inhibiting the Transcriptional Activator Ndd1 by Edenberg, Ellen R., Vashisht, Ajay, Benanti, Jennifer A., Wohlschlegel, James, Toczyski, David P.

“…Classifications Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Normal Human Fibroblasts Are Resistant to RAS-Induced Senescence by Benanti, Jennifer A., Galloway, Denise A.

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Create, activate, destroy, repeat: Cdk1 controls proliferation by limiting transcription factor activity by Benanti, Jennifer A.

“…Progression through the cell cycle is controlled by a network of transcription factors that coordinate gene expression with cell-cycle events. One…”
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Cip1 tunes cell cycle arrest duration upon calcineurin activation by Flynn, Mackenzie J, Benanti, Jennifer A

“…SignificanceTo ensure their survival, cells arrest the cell division cycle when they are exposed to environmental stress. The duration of this arrest is…”
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Epigenetic Down-Regulation of ARF Expression Is a Selection Step in Immortalization of Human Fibroblasts by c-Myc by Benanti, Jennifer A, Wang, Myra L, Myers, Hadley E, Robinson, Kristin L, Grandori, Carla, Galloway, Denise A

“…The transcription factor c-Myc is implicated in the pathogenesis of many cancers. Among the multiple functions of c-Myc, activation of hTert and other genes…”
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Sensitivity of yeast strains with long G-tails to levels of telomere-bound telomerase by Vega, Leticia R, Phillips, Jane A, Thornton, Brian R, Benanti, Jennifer A, Onigbanjo, Mutiat T, Toczyski, David P, Zakian, Virginia A

“…The Saccharomyces cerevisiae Pif1p helicase is a negative regulator of telomere length that acts by removing telomerase from chromosome ends. The catalytic…”
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Calcineurin promotes adaptation to chronic stress through two distinct mechanisms by Flynn, Mackenzie J, Harper, Nicholas W, Li, Rui, Zhu, Lihua Julie, Lee, Michael J, Benanti, Jennifer A

“…Adaptation to environmental stress requires coordination between stress-defense programs and cell cycle progression. The immediate response to many stressors…”
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A balance of deubiquitinating enzymes controls cell cycle entry by Mapa, Claudine E, Arsenault, Heather E, Conti, Michelle M, Poti, Kristin E, Benanti, Jennifer A

“…Protein degradation during the cell cycle is controlled by the opposing activities of ubiquitin ligases and deubiquitinating enzymes (DUBs). Although the…”
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Induction of Extracellular Matrix-Remodeling Genes by the Senescence-Associated Protein APA-1 by Benanti, Jennifer A., Williams, Dawnnica K., Robinson, Kristin L., Ozer, Harvey L., Galloway, Denise A.

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Regulation of a transcription factor network by Cdk1 coordinates late cell cycle gene expression by Landry, Benjamin D, Mapa, Claudine E, Arsenault, Heather E, Poti, Kristin E, Benanti, Jennifer A

“…To maintain genome stability, regulators of chromosome segregation must be expressed in coordination with mitotic events. Expression of these late cell cycle…”
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A proteomic screen reveals SCFGrr1 targets that regulate the glycolytic-gluconeogenic switch by Benanti, Jennifer A, Cheung, Stephanie K, Brady, Mariska C, Toczyski, David P

“…Entry into the cell cycle is regulated by nutrient availability such that cells do not divide when resources are limited. The Skp1-Cul1-F-box (SCF) ubiquitin…”
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