Search Results - "Benaboud, Sihem"

Optimization of the treatment with beta-lactam antibiotics in critically ill patients-guidelines from the French Society of Pharmacology and Therapeutics (Société Française de Pharmacologie et Thérapeutique-SFPT) and the French Society of Anaesthesia and Intensive Care Medicine (Société Française d'Anesthésie et Réanimation-SFAR) by Guilhaumou, Romain, Benaboud, Sihem, Bennis, Youssef, Dahyot-Fizelier, Claire, Dailly, Eric, Gandia, Peggy, Goutelle, Sylvain, Lefeuvre, Sandrine, Mongardon, Nicolas, Roger, Claire, Scala-Bertola, Julien, Lemaitre, Florian, Garnier, Marc

“…Beta-lactam antibiotics (βLA) are the most commonly used antibiotics in the intensive care unit (ICU). ICU patients present many pathophysiological features…”
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A Physiologically-Based Pharmacokinetic Model to Predict Human Fetal Exposure for a Drug Metabolized by Several CYP450 Pathways by De Sousa Mendes, Maïlys, Lui, Gabrielle, Zheng, Yi, Pressiat, Claire, Hirt, Deborah, Valade, Elodie, Bouazza, Naïm, Foissac, Frantz, Blanche, Stephane, Treluyer, Jean-Marc, Urien, Saik, Benaboud, Sihem

“…Background Pregnant women and their fetuses are exposed to numerous drugs; however, they are orphan populations with respect to the safety and efficacy of…”
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Methodological Approaches to Evaluate Fetal Drug Exposure by Bouazza, Naïm, Foissac, Frantz, Hirt, Déborah, Urien, Saïk, Benaboud, Sihem, Lui, Gabrielle, Treluyer, Jean-Marc

“…Drug prescriptions are usual during pregnancy, however, women and their fetuses still remain an orphan population with regard to drugs efficacy and safety…”
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Population pharmacokinetics of meropenem in critically ill children with different renal functions by Rapp, Mélanie, Urien, Saïk, Foissac, Frantz, Béranger, Agathe, Bouazza, Naïm, Benaboud, Sihem, Bille, Emmanuelle, Zheng, Yi, Gana, Inès, Moulin, Florence, Lesage, Fabrice, Renolleau, Sylvain, Tréluyer, Jean Marc, Hirt, Déborah, Oualha, Mehdi

“…Purpose We aimed to develop a meropenem population pharmacokinetic (PK) model in critically ill children and simulate dosing regimens in order to optimize…”
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Prediction of human fetal pharmacokinetics using ex vivo human placenta perfusion studies and physiologically based models by De Sousa Mendes, Maïlys, Hirt, Deborah, Vinot, Cécile, Valade, Elodie, Lui, Gabrielle, Pressiat, Claire, Bouazza, Naïm, Foissac, Frantz, Blanche, Stephane, Lê, Minh Patrick, Peytavin, Gilles, Treluyer, Jean‐Marc, Urien, Saik, Benaboud, Sihem

“…AIMS Pregnant women can be exposed to numerous drugs during the gestational period. For obvious ethical reasons, in vivo studies of fetal exposure to drugs are…”
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Therapeutic Drug Monitoring of Antibiotics in Critically Ill Children: An Observational Study in a Pediatric Intensive Care Unit by de Cacqueray, Noémie, Boujaafar, Sana, Bille, Emmanuelle, Moulin, Florence, Gana, Inès, Benaboud, Sihem, Hirt, Déborah, Béranger, Agathe, Toubiana, Julie, Renolleau, Sylvain, Tréluyer, Jean M., Oualha, Mehdi

“…Septic critically ill children are at a high risk of inadequate antibiotic exposure, requiring them to undergo therapeutic drug monitoring (TDM). The aim of…”
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Concentrations of Tenofovir and Emtricitabine in Breast Milk of HIV-1-Infected Women in Abidjan, Côte d'Ivoire, in the ANRS 12109 TEmAA Study, Step 2 by BENABOUD, Sihem, PRUVOST, Alain, TRELUYER, Jean-Marc, HIRT, Deborah, COFFIE, Patrick A, EKOUEVI, Didier K, URIEN, Saïk, ARRIVE, Elise, BLANCHE, Stephane, THEODORO, Frederic, AVIT, Divine, DABIS, François

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Pregnancy-Related Effects on Tenofovir Pharmacokinetics: a Population Study with 186 Women by BENABOUD, Sihem, HIRT, Deborah, MARC TRELUYER, Jean, LAUNAY, Odile, PANNIER, Emmanuelle, FIRTION, Ghislaine, REY, Elisabeth, BOUAZZA, Naim, FOISSAC, Frantz, CHAPPUY, Hélène, URIEN, Saik

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Transplacental transfer of Remdesivir and GS‐441524: An ex vivo perfusion study by Louchet, Margaux, Ribot, Mégane, Bouazza, Naïm, Foissac, Frantz, Froelicher, Léo, Buth, Victoria, Benaboud, Sihem, Treluyer, Jean‐Marc, Lui, Gabrielle

“…INTRODUCTION Remdesivir (Rmd) is a prodrug of GS-441524 (GS) originally developed against Ebola, proven to reduce in vitro SARS-Cov-2 replication. 1,2…”
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Pregnancy-Related Effects on Lamivudine Pharmacokinetics in a Population Study with 228 Women by BENABOUD, Sihem, MARC TRELUYER, Jean, HIRT, Déborah, URIEN, Saik, BLANCHE, Stéphane, BOUAZZA, Naim, CHAPPUY, Hélène, REY, Elisabeth, PANNIER, Emmanuelle, FIRTION, Ghislaine, LAUNAY, Odile

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Population Pharmacokinetics Study of Recommended Zidovudine Doses in HIV-1-Infected Children by FAUCHET, Floris, TRELUYER, Jean-Marc, FRANGE, Pierre, URIEN, Saik, FOISSAC, Frantz, BOUAZZA, Naim, BENABOUD, Sihem, BLANCHE, Stephane, HIRT, Déborah

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Population Pharmacokinetics of Nevirapine in HIV-1-Infected Pregnant Women and Their Neonates by BENABOUD, Sihem, EKOUEVI, Didier K, NERRIENET, Eric, DABIS, François, TRELUYER, Jean-Marc, HIRT, Déborah, URIEN, Saik, REY, Elisabeth, ARRIVE, Elise, BLANCHE, Stéphane, GRAY, Glenda, KRUY LEANG SIM, AVIT, Divine, MCINTYRE, James

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Pharmacokinetic of ceftazidime‐avibactam in a critically ill patient under high‐volume continuous venovenous haemodiafiltration: A first paediatric case report by Collignon, Charlotte, Benaboud, Sihem, Gana, Inès, Bendavid, Matthieu, Fournier, Benjamin, Oualha, Mehdi, Marcellus, Charles

“…Ceftazidime‐avibactam is a novel cephalosporin/B‐lactamase inhibitor developed in the context of increasing resistance. This case reports the pharmacokinetics…”
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Penetration of isavuconazole into the epithelial lining fluid of patients with pulmonary fungal infections. Comment on: ‘Pharmacokinetics of isavuconazole at different target sites in healthy volunteers after single and multiple intravenous infusions’ by Maillard, Alexis, Froelicher Bournaud, Léo, Pastre, Jean, Planquette, Benjamin, Parize, Perrine, Lanternier, Fanny, Rasmussen, Camille, Chenevier-Gobeaux, Camille, Cheurfa, Cherifa, Benaboud, Sihem, Charlier, Caroline, Canouï, Etienne

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Cefotaxime diffusion in the vitreous humour: a pharmacokinetic case series by Shalaby, Amre, Benaboud, Sihem, Dedieu, Daphné, Anjou, Mickael, Rasmussen, Camille, Brezin, Antoine, Richebe, Pauline, Froelicher Bournaud, Léo, Rouillon, Steeve, Guyonnet, Cécile, Poyart, Claire, Charlier, Caroline, Canouï, Etienne

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Beta-Lactam Antibiotic Exposure During Pediatric Extracorporeal Membrane Oxygenation: Retrospective Cohort Analysis of Drug Levels Using Standard Dosing, 2018–2020 by Marsaux, Alice, Léger, Pierre-Louis, Rambaud, Jérôme, Bille, Emmanuelle, Renolleau, Sylvain, Tréluyer, Jean Marc, Gana, Inès, Lorrot, Matthie, Grimaud, Marion, Toubiana, Julie, Béranger, Agathe, Benaboud, Sihem, Oualha, Mehdi

“…Objectives: Children on extracorporeal membrane oxygenation (ECMO) are at high risk of infection that may worsen prognosis. Even though treatment with…”
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Improving cefazolin exposure in critically ill children using a population pharmacokinetic model by Rivaud, Clémence, Oualha, Mehdi, Salvador, Elodie, Bille, Emmanuelle, Callot, Delphine, Béranger, Agathe, Bournaud, Leo Froelicher, Rouillon, Steeve, Toubiana, Julie, Benaboud, Sihem, Renolleau, Sylvain, Treluyer, Jean Marc, Hirt, Déborah, de Cacqueray, Noémie

“…Population pharmacokinetics (PK) models may be effective in improving antibiotic exposure with individualized dosing. The aim of the study is to assess…”
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Optimization of vigabatrin dosage in children with epileptic spasms: A population pharmacokinetic approach by Molimard, Agathe, Foissac, Frantz, Bouazza, Naïm, Gana, Inès, Benaboud, Sihem, Froelicher, Léo, Hirt, Déborah, Urien, Saïk, Desguerre, Isabelle, Treluyer, Jean‐Marc, Chemaly, Nicole, Nabbout, Rima

“…Aims Vigabatrin is an antiepileptic drug used to treat some forms of severe epilepsy in children. The main adverse effect is ocular toxicity, which is related…”
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A rapid LC-MS/MS method for the simultaneous quantification of ivacaftor, lumacaftor, elexacaftor, tezacaftor, hexyl-methyl ivacaftor and ivacaftor carboxylate in human plasma by Zheng, Yi, Rouillon, Steeve, Khemakhem, Mohamed, Balakirouchenane, David, Lui, Gabrielle, Abdalla, Seef, Sanoufi, Mohammed Rohi, Sauvaitre, Lucie, Thebault, Laure, Hirt, Déborah, Treluyer, Jean-Marc, Gana, Inès, Benaboud, Sihem, Froelicher-bournaud, Léo

“…Cystic fibrosis is one of the most common genetic diseases among caucasian population. This disease is caused by mutations in the cystic fibrosis transmembrane…”
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Dalbavancin: a new option for systemic treatment of Gram-positive endogenous endophthalmitis? by Hamon, Antoine, Benaboud, Sihem, Anjou, Mickael, Thoreau, Benjamin, Dedieu, Daphné, Brezin, Antoine, Froelicher Bournaud, Léo, Tazi, Asmaa, Charlier, Caroline, Canouï, Etienne

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