Search Results - "Ben Morton"

A Novel Assay for Neutrophil Extracellular Trap Formation Independently Predicts Disseminated Intravascular Coagulation and Mortality in Critically Ill Patients by Abrams, Simon T, Morton, Ben, Alhamdi, Yasir, Alsabani, Mohmad, Lane, Steven, Welters, Ingeborg D, Wang, Guozheng, Toh, Cheng-Hock

“…Neutrophil extracellular traps (NETs) are important in the host defense against infection, but they also promote intravascular coagulation and multiorgan…”
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Multicentre evaluation of two multiplex PCR platforms for the rapid microbiological investigation of nosocomial pneumonia in UK ICUs: the INHALE WP1 study by Enne, Virve I, Aydin, Alp, Baldan, Rossella, Owen, Dewi R, Richardson, Hollian, Ricciardi, Federico, Russell, Charlotte, Nomamiukor-Ikeji, Brenda O, Swart, Ann-Marie, High, Juliet, Colles, Antony, Barber, Julie, Gant, Vanya, Livermore, David M, O'Grady, Justin

“…Culture-based microbiological investigation of hospital-acquired or ventilator-associated pneumonia (HAP or VAP) is insensitive, with aetiological agents often…”
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Socioeconomic status and 30-day mortality after minor and major trauma: A retrospective analysis of the Trauma Audit and Research Network (TARN) dataset for England by McHale, Philip, Hungerford, Daniel, Taylor-Robinson, David, Lawrence, Thomas, Astles, Timothy, Morton, Ben

“…Socioeconomic status (SES) is associated with rate and severity of trauma. However, it is unclear whether there is an independent association between SES and…”
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Comprehensive review of safety in Experimental Human Pneumococcal Challenge by Robinson, Ryan E, Myerscough, Christopher, He, Nengjie, Hill, Helen, Shepherd, Wendi A, Gonzalez-Dias, Patricia, Liatsikos, Konstantinos, Latham, Samuel, Fyles, Fred, Doherty, Klara, Hazenberg, Phoebe, Shiham, Fathimath, Mclenghan, Daniella, Adler, Hugh, Randles, Vicki, Zaidi, Seher, Hyder-Wright, Angela, Mitsi, Elena, Burhan, Hassan, Morton, Ben, Rylance, Jamie, Lesosky, Maia, Gordon, Stephen B, Collins, Andrea M, Ferreira, Daniela M

“…Experimental Human Pneumococcal Challenge (EHPC) involves the controlled exposure of adults to a specific antibiotic-sensitive Streptococcus pneumoniae…”
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Long term outcomes for elderly patients after emergency intensive care admission: A cohort study by Dempsey, Ged, Hungerford, Dan, McHale, Phil, McGarey, Lauren, Benison, Edward, Morton, Ben

“…Elderly patients (≥ 80 years of age) surviving an episode of critical illness suffer long-term morbidity and risk of mortality. Identifying high risk groups…”
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Diagnostic accuracy of combined thoracic and cardiac sonography for the diagnosis of pulmonary embolism: A systematic review and meta-analysis by Kagima, Jacqueline, Stolbrink, Marie, Masheti, Sheila, Mbaiyani, Collins, Munubi, Aziz, Joekes, Elizabeth, Mortimer, Kevin, Rylance, Jamie, Morton, Ben, Adrish, Muhammad

“…Objectives Computed tomography pulmonary angiography (CTPA) is the diagnostic standard for pulmonary embolism (PE), but is unavailable in many low resource…”
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First human challenge testing of a pneumococcal vaccine. Double-blind randomized controlled trial by Collins, Andrea M, Wright, Angela D, Mitsi, Elena, Gritzfeld, Jenna F, Hancock, Carole A, Pennington, Shaun H, Wang, Duolao, Morton, Ben, Ferreira, Daniela M, Gordon, Stephen B

“…New vaccines are urgently needed to protect the vulnerable from bacterial pneumonia. Clinical trials of pneumonia vaccines are slow and costly, requiring tens…”
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Becoming the temporary surgeon: A grounded theory examination of anaesthetists performing emergency front of neck access in inter-disciplinary simulation-based training by Silverio, Sergio A, Wallace, Hilary, Gauntlett, William, Berwick, Richard, Mercer, Simon, Morton, Ben, Rogers, Simon N, Sandars, John E, Groom, Peter, Brown, Jeremy M

“…The time-critical 'can't intubate, can't oxygenate' [CICO] emergency post-induction of anaesthesia is rare, but one which, should it occur, requires…”
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A Retrospective Evaluation of Critical Care Blood Culture Yield - Do Support Services Contribute to the "Weekend Effect"? by Morton, Ben, Nagaraja, Shankara, Collins, Andrea, Pennington, Shaun H, Blakey, John D

“…The "weekend effect" describes an increase in adverse outcomes for patients admitted at the weekend. Critical care units have moved to higher intensity working…”
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Authorship reflexivity statements: additional considerations by Taylor, Melissa, Heinz, Eva, Gondwe, Mtisunge, Masekela, Refiloe, Morton, Ben, Oronje, Rose, Vercueil, Andre, Abimbola, Seye, Obasi, Angela

“…Included in the structured statement is a list of specific considerations for authors to address, including the origin of the research question (eg, how it…”
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Health systems strengthening through surgical and perioperative care pathways: a changing paradigm by Kamarajah, Sivesh, Ademuyiwa, Adesoji O, Atun, Rifat, Cieza, Alarcos, Agyei, Fareeda, Ghosh, Dhruva, Henry, Jaymie Claire Ang, Lawani, Souliath, Meara, John, Morton, Ben, Park, Kee B, Morton, Dion G, Reynolds, Teri, Ghaffar, Abdul

“…Global health has traditionally focused on the primary health development with disease-specific focus such as HIV, malaria and non-communicable diseases…”
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Exploring smoke: an ethnographic study of air pollution in rural Malawi by Saleh, Sepeedeh, Sambakunsi, Henry, Mortimer, Kevin, Morton, Ben, Kumwenda, Moses, Rylance, Jamie, Chinouya, Martha

“…Air pollution adversely affects human health, and the climate crisis intensifies the global imperative for action. Low-/middle-income countries (LMIC) suffer…”
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A feasibility study of controlled human infection with Streptococcus pneumoniae in Malawi by Morton, Ben, Burr, Sarah, Chikaonda, Tarsizio, Nsomba, Edna, Manda-Taylor, Lucinda, Henrion, Marc Y.R., Banda, Ndaziona Peter, Rylance, Jamie, Ferreira, Daniela M., Jambo, Kondwani, Gordon, Stephen B.

“…Persistent carriage of pneumococcal vaccine serotypes has occurred after introduction of PCV13 vaccination in Africa but the mechanisms are unclear. We tested…”
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A mixed-methods pilot study to evaluate a collaborative anaesthetic and surgical training package for emergency surgical cricothyroidotomy by Berwick, Richard J, Gauntlett, William, Silverio, Sergio A, Wallace, Hilary, Mercer, Simon, Brown, Jeremy M, Sandars, John E, Morton, Ben, Groom, Peter

“…In a 'can't intubate, can't oxygenate' scenario, success of emergency front-of-neck access is dependent upon a clinician's skill, competence and confidence to…”
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Protocol for a phase IV double-blind randomised controlled trial to investigate the effect of the 13-valent pneumococcal conjugate vaccine and the 23-valent pneumococcal polysaccharide vaccine on pneumococcal colonisation using the experimental human pneumococcal challenge model in healthy adults (PREVENTING PNEUMO 2) by Liatsikos, Konstantinos, Hyder-Wright, Angela, Pojar, Sherin, Chen, Tao, Wang, Duolao, Davies, Kelly, Myerscough, Christopher, Reine, Jesus, Robinson, Ryan E, Urban, Britta, Mitsi, Elena, Solorzano, Carla, Gordon, Stephen B, Quinn, Angela, Pan, Kaijie, Anderson, Annaliesa S, Theilacker, Christian, Begier, Elizabeth, Gessner, Bradford D, Collins, Andrea, Ferreira, Daniela M, Convey, Kelly, Court, James, Farrar, Madlen, Fyles, Fred, Hamilton, Josh, Hazenberg, Phoebe, Hill, Helen, Hitchins, Lisa, Howard, Ashleigh, Nyazika, Tinashe K, Kerruish, Lauren, Latham, Samuel, Murphy, Annabel, Nikolaou, Elissavet, Peterson, Angelina, Burhan, Hassan, Morton, Ben

“…IntroductionDespite widely available vaccinations, Streptococcus pneumoniae (SPN) remains a major cause of morbidity and mortality worldwide, causing…”
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Multimorbidity-associated emergency hospital admissions: a “screen and link” strategy to improve outcomes for high-risk patients in sub-Saharan Africa: a prospective multicentre cohort study protocol by Spencer, Stephen A., Rutta, Alice, Hyuha, Gimbo, Banda, Gift Treighcy, Choko, Augustine, Dark, Paul, Hertz, Julian T., Mmbaga, Blandina T., Mfinanga, Juma, Mijumbi, Rhona, Muula, Adamson, Nyirenda, Mulinda, Rosu, Laura, Rubach, Matthew, Salimu, Sangwani, Sakita, Francis, Salima, Charity, Sawe, Hendry, Simiyu, Ibrahim, Taegtmeyer, Miriam, Urasa, Sarah, White, Sarah, Yongolo, Nateiya M., Rylance, Jamie, Morton, Ben, Worrall, Eve, Limbani, Felix

“…Background The prevalence of multimorbidity (the presence of two or more chronic health conditions) is rapidly increasing in sub–Saharan Africa. Hospital care…”
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“At first, I was very afraid”—a qualitative description of participants’ views and experiences in the first Human Infection Study in Malawi by Mtunthama Toto, Neema, Gooding, Kate, Kapumba, Blessings M., Jambo, Kondwani, Rylance, Jamie, Burr, Sarah, Morton, Ben, Gordon, Stephen B., Manda-Taylor, Lucinda

“…Background: Human infection studies (HIS) involve deliberately infecting healthy volunteers with a pathogen in a controlled environment to understand infection…”
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High SARS-CoV-2 seroprevalence in health care workers but relatively low numbers of deaths in urban Malawi by Chibwana, Marah G., Jere, Khuzwayo C., Kamng'ona, Raphael, Mandolo, Jonathan, Katunga-Phiri, Vincent, Tembo, Dumizulu, Mitole, Ndaona, Musasa, Samantha, Sichone, Simon, Lakudzala, Agness, Sibale, Lusako, Matambo, Prisca, Kadwala, Innocent, Byrne, Rachel L., Mbewe, Alice, Henrion, Marc Y. R., Morton, Ben, Phiri, Chimota, Mallewa, Jane, Mwandumba, Henry C., Adams, Emily R., Gordon, Stephen B., Jambo, Kondwani C.

“…Background : In low-income countries, like Malawi, important public health measures including social distancing or a lockdown have been challenging to…”
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Assessing ethical climates in critical care and their impact on patient outcomes by Okenyi, Emmanuel, Donaldson, Thomas Michael, Collins, Andrea, Morton, Ben, Obasi, Angela

“…http://ow.ly/vnFP30neAZN…”
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"An increase in COVID-19 patients would be overwhelming": A qualitative description of healthcare workers' experiences during the first wave of COVID-19 (March 2020 to October 2020) at Malawi's largest referral hospital by Limbani, Felix, Kapumba, Blessings M, Mzinganjira, Henry, Phiri, Tamara, Mwandumba, Henry C, Rylance, Jamie, Morton, Ben, Desmond, Nicola

“…Background  COVID-19 is currently a global health threat. Healthcare workers are on the front-line of the COVID-19 outbreak response and therefore at…”
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