Hemoglobin C disease: report of 16 Tunisian cases

was to provide the clinical and biological patterns hemoglobine disease in Tunisia. This retrospective study collected to 16 cases of hemoglobin C disease : 6 homozygotic Hb C and 10 heterozygotic Hb C/beta-thalassemia. The clinical profile is characterized by mild hemolytic anemia (Hb = 11.7 g/dl)...

Full description

Saved in:

Bibliographic Details
Published in:	Tunisie Medicale Vol. 85; no. 3; p. 209
Main Authors:	Hafsia, Raouf, Marrakchi, Olfa, Ben Salah, Naouel, Gouider, Emna, Ben Lakhal, Ryhane, Jeddi, Ramzi, Aissaoui, Lamia, Belhadjali, Zaher, Ben Abid, Hela, Meddeb, Balkis, Hafsia, Aïcha
Format:	Journal Article
Language:	French
Published:	Tunisia 01-03-2007
Subjects:	Adolescent Adult Female Hemoglobin C - analysis Hemoglobin C Disease - diagnosis Hemoglobin C Disease - genetics Humans Hypersplenism - etiology Male Middle Aged Retrospective Studies Splenomegaly - etiology Tunisia Tunisia
Online Access:	Get more information
Tags:	Add Tag No Tags, Be the first to tag this record!

Description
Summary:	was to provide the clinical and biological patterns hemoglobine disease in Tunisia. This retrospective study collected to 16 cases of hemoglobin C disease : 6 homozygotic Hb C and 10 heterozygotic Hb C/beta-thalassemia. The clinical profile is characterized by mild hemolytic anemia (Hb = 11.7 g/dl) associated with splenomegaly and hypersplenism. Contrary to homozygous state, the Hb C/beta-thalassemia is associated with microcytosis and pseudopolycythemia. The diagnosis is based on target cells, specific intraerythrocytic Hb C crystals in blood smear and Hb C level at 100%. The Hb C disease must be considered as a benign hemoglobinopathy which is associated with a long survival without major complications.
ISSN:	0041-4131