Antioxidant and selective anticancer activities of two Euphorbia species in human acute myeloid leukemia

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Bibliographic Details
Published in:	Biomedicine & pharmacotherapy Vol. 90; pp. 375 - 385
Main Authors:	Ben Jannet, Soumaya, Hymery, Nolwenn, Bourgou, Soumaya, Jdey, Ahmed, Lachaal, Mokhtar, Magné, Christian, Ksouri, Riadh
Format:	Journal Article
Language:	English
Published:	France Elsevier Masson SAS 01-06-2017 Elsevier
Subjects:	Alkaloids - pharmacology Animals Antineoplastic Agents - pharmacology Antioxidants Antioxidants - pharmacology Apoptosis Caco-2 Cells Cell Line Cell Line, Tumor Cell Proliferation - drug effects E. paralias E. terracina Euphorbia - chemistry Humans In vitro cytotoxicity Inflammatory Internal Medicine Leukemia Leukemia, Myeloid, Acute - drug therapy Leukemia, Myeloid, Acute - metabolism Life Sciences Medical Education Microbiology and Parasitology Monocytes - drug effects Monocytes - metabolism Mycology Phenols - pharmacology Plant Extracts - pharmacology Rats Reactive Oxygen Species - metabolism Saponins - pharmacology Terpenes - pharmacology Tumor Necrosis Factor-alpha - metabolism apolar fraction DMSO polar fraction 2,2′-azinobis-(3-ethylbenzothiazoline-6-sulfonic acid) Leukemia 5-Methylphenazinium methyl sulfate E. terracina In vitro cytotoxicity Apol.F MTS BHT Antioxidants NADH propidium iodide reactive oxygen species Pol.F 3-(4,5-dimethylthiazol-2-yl)-5-(3-carboxymethoxyphenyl)-2-(4-sulfophenyl)-2H-tetrazolium, inner salt NBT DPPH percentage of inhibition nicotinamide adenine dinucleotide hydrate ACP E. paralias 2,2-diphenyl-1-picrylhydrazyl Butylated hydroxytoluene Dimethyl sulfoxide PMS ROS Inflammatory p-Nitrotetrazolium blue PI ABTS principal component analysis Apoptosis
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Summary:	Graphical abstract
Bibliography:	ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23
ISSN:	0753-3322 1950-6007
DOI:	10.1016/j.biopha.2017.03.072