Search Results - "Ben Halima, Saoussen"

Specific Inhibition of β-Secretase Processing of the Alzheimer Disease Amyloid Precursor Protein by Ben Halima, Saoussen, Mishra, Sabyashachi, Raja, K. Muruga Poopathi, Willem, Michael, Baici, Antonio, Simons, Kai, Brüstle, Oliver, Koch, Philipp, Haass, Christian, Caflisch, Amedeo, Rajendran, Lawrence

“…Development of disease-modifying therapeutics is urgently needed for treating Alzheimer disease (AD). AD is characterized by toxic β-amyloid (Aβ) peptides…”
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miR‐186 in Alzheimer's disease: a big hope for a small RNA? by Ben Halima, Saoussen, Siegel, Gabriele, Rajendran, Lawrence

“…This Editorial highlights a study by Kim et al. in the current issue of Journal of Neurochemistry, in which the authors demonstrate that miR‐186 is a potent…”
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Processing of the Synaptic Cell Adhesion Molecule Neurexin-3β by Alzheimer Disease α- and γ-Secretases by Bot, Nathalie, Schweizer, Claude, Ben Halima, Saoussen, Fraering, Patrick C.

“…Neurexins (NRXNs) are synaptic cell adhesion molecules having essential roles in the assembly and maturation of synapses into fully functional units…”
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Membrane anchored and lipid raft targeted β-secretase inhibitors for Alzheimer's disease therapy by Ben Halima, Saoussen, Rajendran, Lawrence

“…β-secretase, a key enzyme involved in amyloid-β generation, is an attractive candidate for Alzheimer's disease therapy. Transition-state inhibitors of…”
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Cellular basis of Alzheimer's disease by Bali, Jitin, Halima, Saoussen Ben, Felmy, Boas, Goodger, Zoe, Zurbriggen, Sebastian, Rajendran, Lawrence

“…Alzheimer's disease (AD) is the most common form of neurodegenerative disease. A characteristic feature of the disease is the presence of amyloid-β (Aβ) which…”
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Processing of the synaptic cell adhesion molecule neurexin-3beta by Alzheimer disease alpha- and gamma-secretases by Bot, Nathalie, Schweizer, Claude, Ben Halima, Saoussen, Fraering, Patrick C

“…Neurexins (NRXNs) are synaptic cell adhesion molecules having essential roles in the assembly and maturation of synapses into fully functional units…”
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