Search Results - "Bem, Reinout A"

Small droplet aerosols in poorly ventilated spaces and SARS-CoV-2 transmission by Somsen, G Aernout, van Rijn, Cees, Kooij, Stefan, Bem, Reinout A, Bonn, Daniel

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Animal models of human respiratory syncytial virus disease by Bem, Reinout A, Domachowske, Joseph B, Rosenberg, Helene F

“…Infection with the human pneumovirus pathogen, respiratory syncytial virus (hRSV), causes a wide spectrum of respiratory disease, notably among infants and the…”
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Neutrophil extracellular traps cause airway obstruction during respiratory syncytial virus disease by Cortjens, Bart, de Boer, Onno J, de Jong, Rineke, Antonis, Adriaan FG, Sabogal Piñeros, Yanaika S, Lutter, René, van Woensel, Job BM, Bem, Reinout A

“…Human respiratory syncytial virus (RSV) is the most important cause of severe lower respiratory tract disease (LRTD) in young children worldwide. Extensive…”
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Low energy nebulization preserves integrity of SARS-CoV-2 mRNA vaccines for respiratory delivery by van Rijn, Cees J. M., Vlaming, Killian E., Bem, Reinout A., Dekker, Rob J., Poortinga, Albert, Breit, Timo, van Leeuwen, Selina, Ensink, Wim A., van Wijnbergen, Kelly, van Hamme, John L., Bonn, Daniel, Geijtenbeek, Teunis B. H.

“…Nebulization of mRNA therapeutics can be used to directly target the respiratory tract. A promising prospect is that mucosal administration of lipid…”
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Bacterial co-infection of the respiratory tract in ventilated children with bronchiolitis; a retrospective cohort study by Wiegers, Hanke M G, van Nijen, Lisa, van Woensel, Job B M, Bem, Reinout A, de Jong, Menno D, Calis, Job C J

“…Viral bronchiolitis is the most common cause of respiratory failure requiring invasive ventilation in young children. Bacterial co-infections may complicate…”
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Low‑to‑moderate hyperoxia in animal models: is there evidence for harm? by Lilien, Thijs A., Bem, Reinout A.

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Author Correction: Low energy nebulization preserves integrity of SARS-CoV-2 mRNA vaccines for respiratory delivery by van Rijn, Cees J. M., Vlaming, Killian E., Bem, Reinout A., Dekker, Rob J., Poortinga, Albert, Breit, Timo, van Leeuwen, Selina, Ensink, Wim A., van Wijnbergen, Kelly, van Hamme, John L., Bonn, Daniel, Geijtenbeek, Teunis B. H.

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Pneumovirus-Induced Lung Disease in Mice Is Independent of Neutrophil-Driven Inflammation by Cortjens, Bart, Lutter, René, Boon, Louis, Bem, Reinout A, van Woensel, Job B M

“…The human pneumovirus respiratory syncytial virus (RSV) is the most common pathogen causing lower respiratory tract disease in young children worldwide. A…”
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Fluid restriction reduces pulmonary edema in a model of acute lung injury in mechanically ventilated rats by Ingelse, Sarah A, Juschten, Jenny, Maas, Martinus A W, Matute-Bello, Gustavo, Juffermans, Nicole P, van Woensel, Job B M, Bem, Reinout A

“…Experimental acute lung injury models are often used to increase our knowledge on the acute respiratory distress syndrome (ARDS), however, existing animal…”
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The Changing Landscape of Respiratory Syncytial Virus Infections by Bem, Reinout A, van Woensel, Job B. M

“…Respiratory syncytial virus (RSV), a negative-sense, enveloped RNA virus of the family Paramyxoviridae, subfamily Pneumovirinae, and genus Pneumovirus, is the…”
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Current Practice of Fluid Maintenance and Replacement Therapy in Mechanically Ventilated Critically Ill Children: A European Survey by Arrahmani, Ismail, Ingelse, Sarah A, van Woensel, Job B M, Bem, Reinout A, Lemson, Joris

“…Appropriate fluid management in mechanically ventilated critically ill children remains an important challenge and topic of active discussion in pediatric…”
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Reduced Air Leakage During Non-Invasive Ventilation Using a Simple Anesthetic Mask With 3D-Printed Adaptor in an Anthropometric Based Pediatric Head-Lung Model by Hovenier, Renée, Goto, Lyè, Huysmans, Toon, van Gestel, Monica, Klein-Blommert, Rozalinde, Markhorst, Dick, Dijkman, Coen, Bem, Reinout A

“…Non-invasive ventilation (NIV) is increasingly used in the support of acute respiratory failure in critically ill children admitted to the pediatric intensive…”
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Long-Term Pulmonary Dysfunction by Hyperoxia Exposure during Severe Viral Lower Respiratory Tract Infection in Mice by Lilien, Thijs A, Gunjak, Miša, Myti, Despoina, Casado, Francisco, van Woensel, Job B M, Morty, Rory E, Bem, Reinout A

“…Viral-induced lower respiratory tract infection (LRTI), mainly by respiratory syncytial virus (RSV), causes a major health burden among young children and has…”
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Less Is More?-A Feasibility Study of Fluid Strategy in Critically Ill Children With Acute Respiratory Tract Infection by Ingelse, Sarah A, Geukers, Vincent G, Dijsselhof, Monique E, Lemson, Joris, Bem, Reinout A, van Woensel, Job B

“…Fluid overload is common in critically ill children and is associated with adverse outcome. Therefore, restricting fluid intake may be beneficial. This study…”
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Development of personalized non-invasive ventilation masks for critically ill children: a bench study by Pigmans, Rosemijne R. W. P., Klein-Blommert, Rozalinde, van Gestel, Monica C., Markhorst, Dick G., Hammond, Peter, Boomsma, Pim, Daams, Tim, de Jong, Julia M. A., Heeman, Paul M., van Woensel, Job B. M., Dijkman, Coen D., Bem, Reinout A.

“…Background Obtaining a properly fitting non-invasive ventilation (NIV) mask to treat acute respiratory failure is a major challenge, especially in young…”
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Evaluating fluid overload in critically ill children by Bem, Reinout A, Lemson, Joris

“…To review the evaluation and management of fluid overload in critically ill children. Emerging evidence associates fluid overload, i.e. having a positive…”
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The Association between Weather Conditions and Admissions to the Paediatric Intensive Care Unit for Respiratory Syncytial Virus Bronchiolitis by Linssen, Rosalie, den Hollander, Bibiche, Bont, Louis, van Woensel, Job, Bem, Reinout

“…Respiratory syncytial virus (RSV) bronchiolitis is a leading cause of global child morbidity and mortality. Every year, seasonal RSV outbreaks put high…”
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HS-GC–MS analysis of volatile organic compounds after hyperoxia-induced oxidative stress: a validation study by Lilien, Thijs A., Fenn, Dominic W., Brinkman, Paul, Hagens, Laura A., Smit, Marry R., Heijnen, Nanon F. L., van Woensel, Job B. M., Bos, Lieuwe D. J., Bem, Reinout A.

“…Background Exhaled volatile organic compounds (VOCs), particularly hydrocarbons from oxidative stress-induced lipid peroxidation, are associated with hyperoxia…”
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Pediatric Acute Respiratory Distress Syndrome: Fluid Management in the PICU by Ingelse, Sarah A, Wösten-van Asperen, Roelie M, Lemson, Joris, Daams, Joost G, Bem, Reinout A, van Woensel, Job B

“…The administration of an appropriate volume of intravenous fluids, while avoiding fluid overload, is a major challenge in the pediatric intensive care unit…”
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Neutrophil Extracellular Traps Do Not Induce Injury and Inflammation in Well-Differentiated RSV-Infected Airway Epithelium by Linssen, Rosalie S N, Sridhar, Adithya, Moreni, Giulia, van der Wel, Nicole N, van Woensel, Job B M, Wolthers, Katja C, Bem, Reinout A

“…Respiratory syncytial virus (RSV) lower respiratory tract infection (LRTI) causes a major burden of disease. The host response in RSV-LRTI is characterized by…”
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