Search Results - "Bem, F"
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Organoselenium compounds as mimics of selenoproteins and thiol modifier agents
Published in Metallomics (01-12-2017)“…Selenium is an essential trace element for animals and its role in the chemistry of life relies on a unique functional group: the selenol (-SeH) group. The…”
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Metabolic activity in cryopreserved and grafted ovarian tissue using high-resolution respirometry
Published in Scientific reports (02-11-2021)“…Cryopreservation of ovarian tissue followed by transplantation represents a strategy to restore ovarian function and fertility. Stress from…”
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Molecular aspects involved in swimming exercise training reducing anhedonia in a rat model of depression
Published in Neuroscience (29-09-2011)“…Abstract Patients suffering from depression frequently display hyperactivity of the hypothalamic–pituitary–adrenal axis (HPA) resulting in elevated cortisol…”
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Positive correlation between elevated plasma cholesterol levels and cognitive impairments in LDL receptor knockout mice: relevance of cortico-cerebral mitochondrial dysfunction and oxidative stress
Published in Neuroscience (01-12-2011)“…Abstract Convergent epidemiological, clinical, and experimental findings indicate that hypercholesterolemia contributes to the onset of Alzheimer's disease…”
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Jaboticaba (Myrciaria jaboticaba) powder consumption improves the metabolic profile and regulates gut microbiome composition in high-fat diet-fed mice
Published in Biomedicine & pharmacotherapy (01-12-2021)“…The consumption of a high-fat diet can cause metabolic syndrome and induces host gut microbial dysbiosis and non-alcoholic fatty liver disease (NAFLD). We…”
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β-Caryophyllene protects the C6 glioma cells against glutamate-induced excitotoxicity through the Nrf2 pathway
Published in Neuroscience (24-10-2014)“…Graphical abstract…”
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The intranasal administration of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP): a new rodent model to test palliative and neuroprotective agents for Parkinson's disease
Published in Current pharmaceutical design (01-02-2011)“…Parkinson's disease (PD) is the second most common neurodegenerative disorder affecting approximately 1% of the population older than 60 years. Classically, PD…”
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Impaired adult hippocampal neurogenesis in a mouse model of familial hypercholesterolemia: A role for the LDL receptor and cholesterol metabolism in adult neural precursor cells
Published in Molecular metabolism (Germany) (01-12-2019)“…In familial hypercholesterolemia (FH), mutations in the low-density lipoprotein (LDL) receptor (LDLr) gene result in increased plasma LDL cholesterol. Clinical…”
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Effects of diet-induced hypercholesterolemia and gold nanoparticles treatment on peripheral tissues
Published in Anais da Academia Brasileira de Ciências (01-01-2022)“…Cholesterol is a lipid molecule of great biological importance to animal cells. Dysregulation of cholesterol metabolism leads to raised blood total cholesterol…”
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High-intensity physical exercise disrupts implicit memory in mice: involvement of the striatal glutathione antioxidant system and intracellular signaling
Published in Neuroscience (29-12-2010)“…Abstract Physical exercise is a widely accepted behavioral strategy to enhance overall health, including mental function. However, there is controversial…”
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Caffeine Mitigates the Locomotor Hyperactivity in Middle‐aged Low‐density Lipoprotein Receptor (LDLr)‐Knockout Mice
Published in CNS neuroscience & therapeutics (01-05-2016)Get full text
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Tempol, a superoxide dismutase-mimetic drug, prevents chronic ischemic renal injury in two-kidney, one-clip hypertensive rats
Published in Clinical and experimental hypertension (1993) (17-11-2018)“…Tempol, a superoxide dismutase-mimetic drug, has been shown to attenuate radical-induced damage, exerting beneficial effects in the animal models of oxidative…”
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Probucol mitigates streptozotocin-induced cognitive and biochemical changes in mice
Published in Neuroscience (22-01-2015)“…Highlights • i.c.v. STZ increased hippocampal BACE levels, AChE activity and oxidative stress. • i.c.v. STZ caused cognitive impairment in mice. • Probucol…”
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Supplementation of diets for piglets with L-Arginine and powdered whole milk
Published in South African journal of animal science (01-11-2020)“…The objective of this study was to evaluate the supplementation of L-Arginine in diets with and without dairy products for piglets weaned at 21 days old…”
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Proanthocyanidin-rich fraction from Croton celtidifolius Baill confers neuroprotection in the intranasal 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine rat model of Parkinson’s disease
Published in Journal of Neural Transmission (01-12-2010)“…We have recently demonstrated that rodents treated intranasally with 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) suffered impairments in olfactory,…”
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Synergistic neurotoxicity induced by methylmercury and quercetin in mice
Published in Food and chemical toxicology (01-03-2009)“…Methylmercury (MeHg) is a highly neurotoxic pollutant, whose mechanisms of toxicity are related to its pro-oxidative properties. A previous report showed under…”
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Atheroprotective action of a modified organoselenium compound: in vitro evidence
Published in Anais da Academia Brasileira de Ciências (2016)“…Oxidation of low-density lipoprotein (LDL) has been strongly suggested to play a significant role in the pathogenesis of atherosclerosis. Thus, reducing LDL…”
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The potential toxicological insights about the anti-HIV drug azidothymidine-derived monoselenides in human leukocytes: Toxicological insights of new selenium-azidothymidine analogs
Published in Human & experimental toxicology (01-09-2017)“…Acquired immunodeficiency syndrome (AIDS) is a worldwide disease characterized by impairments of immune function. AIDS can be associated with oxidative stress…”
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Enzymes that hydrolyze adenine nucleotides of patients with hypercholesterolemia and inflammatory processes
Published in The FEBS journal (01-06-2007)“…The activity of NTPDase (EC 3.6.1.5, apyrase, CD39) was verified in platelets from patients with increasing cholesterol levels. A possible association between…”
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