Search Results - "Beltran, Chris J."

The Mayo Clinic Florida Microdosimetric Kinetic Model of Clonogenic Survival: Application to Various Repair-Competent Rodent and Human Cell Lines by Parisi, Alessio, Beltran, Chris J, Furutani, Keith M

“…The relative biological effectiveness (RBE) calculations used during the planning of ion therapy treatments are generally based on the microdosimetric kinetic…”
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A linear relationship for the LET-dependence of Gafchromic EBT3 film in spot-scanning proton therapy by Anderson, Sarah E, Grams, Michael P, Wan Chan Tseung, H, Furutani, Keith M, Beltran, Chris J

“…Radiochromic film (RCF) is a valuable dosimetric tool, primarily due to its sub-millimeter spatial resolution. For accurate proton dosimetry, the dependence of…”
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Comparative Evaluation of Two Analytical Functions for the Microdosimetry of Ions from 1H to 238U by Parisi, Alessio, Furutani, Keith M., Sato, Tatsuhiko, Beltran, Chris J.

“…The analytical microdosimetric function (AMF) implemented in the Monte Carlo code PHITS is a unique tool that bridges the gap between macro- and microscopic…”
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Clonogenic Survival RBE Calculations in Carbon Ion Therapy: The Importance of the Absolute Values of α and β in the Photon Dose-Response Curve and a Strategy to Mitigate Their Anticorrelation by Parisi, Alessio, Beltran, Chris J., Furutani, Keith M.

“…The computation of the relative biological effectiveness (RBE) is a fundamental step in the planning of cancer radiotherapy treatments with accelerated ions…”
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Does the Maximum Initial Beam Energy for Proton Therapy Have to Be 230 MeV? by Beltran, Chris J, Perales, Alvaro, Furutani, Keith M

“…Proton therapy is increasingly widespread and requires an accelerator to provide the high energy protons. Most often, the accelerators used for proton therapy…”
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Variation of the relative biological effectiveness in the penumbra of ion therapy beams estimated using different microdosimetric approaches by Parisi, Alessio, Furutani, Keith M., Beltran, Chris J.

“…The effort to translate clinical findings across institutions employing different relative biological effectiveness (RBE) models of ion radiotherapy has…”
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Technical Note: Improving the workflow in a carbon ion therapy center with custom software for enhanced patient care by Yaddanapudi, Sridhar, Wakisaka, Yushi, Furutani, Keith M., Yagi, Masashi, Shimizu, Shinichi, Beltran, Chris J.

“…•Carbon-ion radiation therapy is a new and upcoming treatment option for challenging and resistant cancers.•The workflow for carbon-ion radiation therapy is…”
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Validation of clinical acceptability of deep-learning-based automated segmentation of organs-at-risk for head-and-neck radiotherapy treatment planning by Lucido, J John, DeWees, Todd A, Leavitt, Todd R, Anand, Aman, Beltran, Chris J, Brooke, Mark D, Buroker, Justine R, Foote, Robert L, Foss, Olivia R, Gleason, Angela M, Hodge, Teresa L, Hughes, Cían O, Hunzeker, Ashley E, Laack, Nadia N, Lenz, Tamra K, Livne, Michelle, Morigami, Megumi, Moseley, Douglas J, Undahl, Lisa M, Patel, Yojan, Tryggestad, Erik J, Walker, Megan Z, Zverovitch, Alexei, Patel, Samir H

“…Organ-at-risk segmentation for head and neck cancer radiation therapy is a complex and time-consuming process (requiring up to 42 individual structure, and may…”
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Pragmatic, Prospective Comparative Effectiveness Trial of Carbon Ion Therapy, Surgery, and Proton Therapy for the Management of Pelvic Sarcomas (Soft Tissue/Bone) Involving the Bone: The PROSPER Study Rationale and Design by Hoppe, Bradford S, Petersen, Ivy A, Wilke, Benjamin K, DeWees, Todd A, Imai, Reiko, Hug, Eugen B, Fiore, Maria Rosaria, Debus, Jürgen, Fossati, Piero, Yamada, Shigeru, Orlandi, Ester, Zhang, Qing, Bao, Cihang, Seidensaal, Katharina, May, Byron C, Harrell, Anna C, Houdek, Matthew T, Vallow, Laura A, Rose, Peter S, Haddock, Michael G, Ashman, Jonathan B, Goulding, Krista A, Attia, Steven, Krishnan, Sunil, Mahajan, Anita, Foote, Robert L, Laack, Nadia N, Keole, Sameer R, Beltran, Chris J, Welch, Eric M, Karim, Mohammed, Ahmed, Safia K

“…Surgical treatment of pelvic sarcoma involving the bone is the standard of care but is associated with several sequelae and reduced functional quality of life…”
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Nuclear Fragmentation Imaging for Carbon-Ion Radiation Therapy Monitoring: an In Silico Study by Bey, Anissa, Ma, Jiasen, Furutani, Keith M, Herman, Michael G, Johnson, Jedediah E, Foote, Robert L, Beltran, Chris J

“…This article presents an in vivo imaging technique based on nuclear fragmentation of carbon ions in irradiated tissues for potential real-time monitoring of…”
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Feasibility of proton transmission-beam stereotactic ablative radiotherapy versus photon stereotactic ablative radiotherapy for lung tumors: a dosimetric and feasibility study by Mou, Benjamin, Beltran, Chris J, Park, Sean S, Olivier, Kenneth R, Furutani, Keith M

“…Stereotactic ablative radiotherapy is being increasingly adopted in the treatment of lung tumors. The use of proton beam therapy can further reduce dose to…”
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Variable RBE in proton radiotherapy: a comparative study with the predictive Mayo Clinic Florida microdosimetric kinetic model and phenomenological models of cell survival by Parisi, Alessio, Beltran, Chris J, Furutani, Keith M

“… (1) To examine to what extent the cell- and exposure- specific information neglected in the phenomenological proton relative biological effectiveness (RBE)…”
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LET‐based approximation of the microdosimetric kinetic model for proton radiotherapy by Parisi, Alessio, Furutani, Keith M., Sato, Tatsuhiko, Beltran, Chris J.

“…Background Phenomenological relative biological effectiveness (RBE) models for proton therapy, based on the dose‐averaged linear energy transfer (LET), have…”
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On the calculation of the relative biological effectiveness of ion radiation therapy using a biological weighting function, the microdosimetric kinetic model (MKM) and subsequent corrections (non-Poisson MKM and modified MKM) by Parisi, Alessio, Furutani, Keith M, Beltran, Chris J

“… To investigate similarities and differences in the formalism, processing, and the results of relative biological effectiveness (RBE) calculations with a…”
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A High-Precision Method for In Vitro Proton Irradiation by Howard, Michelle E, Denbeigh, Janet M, Debrot, Emily K, Remmes, Nicholas B, Herman, Michael G, Beltran, Chris J

“…Although proton therapy has become a well-established radiation modality, continued efforts are needed to improve our understanding of the molecular and…”
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Technical Delivery Parameters of 2000 Proton Treatment Courses by Deisher, Amanda J, Whitaker, Thomas J, Beltran, Chris J, Foote, Robert L, Haddock, Michael G, Mahajan, Anita

“…To summarize the technical delivery parameters of proton plans delivered at the Mayo Clinic in Rochester, Minnesota. The database of treated patient proton…”
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Technical note: Delivery benefit and dosimetric implication of synchrotron‐based proton pencil beam scanning using continuous scanning mode by Liang, Xiaoying, Beltran, Chris J., Liu, Chunbo, Shen, Jiajian, Li, Heng, Furutani, Keith M.

“…Background Discrete spot scanning (DSS) is the commonly used method for proton pencil beam scanning (PBS). There is lack of data on the dose‐driven continuous…”
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The Importance of Verification CT-QA Scans in Patients Treated with IMPT for Head and Neck Cancers by Evans, Jaden D, Harper, Riley H, Petersen, Molly, Harmsen, William S, Anand, Aman, Hunzeker, Ashley, Deiter, Noelle C, Schultz, Heather, Jethwa, Krishan R, Lester, Scott C, Routman, David M, Ma, Daniel J, Garces, Yolanda I, Neben-Wittich, Michelle A, Laack, Nadia N, Beltran, Chris J, Patel, Samir H, McGee, Lisa A, Rwigema, Jean-Claude M, Mundy, Daniel W, Foote, Robert L

“…To understand how verification computed tomography-quality assurance (CT-QA) scans influenced clinical decision-making to replan patients with head and neck…”
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The effect of fitting the reference photon dose–response on the clonogenic survival predicted with the Mayo Clinic Florida microdosimetric kinetic model in case of accelerated ions by Parisi, Alessio, Beltran, Chris J, Furutani, Keith M

“…Abstract The Mayo Clinic Florida microdosimetric kinetic model (MCF MKM) is a recently developed clonogenic survival model. Since the MCF MKM relies on novel…”
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Spot-scanned pancreatic stereotactic body proton therapy: A dosimetric feasibility and robustness study by Sio, Terence T, Merrell, Kenneth W, Beltran, Chris J, Ashman, Jonathan B, Hoeft, Kathleen A, Miller, Robert C, Whitaker, Thomas J, Wurgler, Stephanie K, Tryggestad, Erik J

“…Highlights • We compared pancreatic cancer SBRT with protons (SBPT) and photons (SB-IMRT). • SBPT planning is associated with significant gastrointestinal…”
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