Search Results - "Belshaw, N. J."

role of CRE1 in nucleosome positioning within the cbh1 promoter and coding regions of Trichoderma reesei by Ries, L, Belshaw, N. J, Ilmén, M, Penttilä, M. E, Alapuranen, M, Archer, D. B

“…Nucleosome positioning within the promoter and coding regions of the cellobiohydrolase-encoding cbh1 gene of Trichoderma reesei was investigated. T. reesei is…”
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Profiling CpG island field methylation in both morphologically normal and neoplastic human colonic mucosa by Belshaw, N J, Elliott, G O, Foxall, R J, Dainty, J R, Pal, N, Coupe, A, Garg, D, Bradburn, D M, Mathers, J C, Johnson, I T

“…Aberrant CpG island (CGI) methylation occurs early in colorectal neoplasia. Quantitative methylation-specific PCR profiling applied to biopsies was used to…”
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Nutrition and epigenetics: An emerging field by Johnson, I. T, Belshaw, N. J

“…Epigenetics refers to heritable changes to gene expression encoded not by differences in the genetic sequence but by other chemical modifications to chromatin,…”
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Relationships between Dietary Inflammatory Index score and markers of inflammation and WNT signalling in the healthy colorectal mucosa by Malcomson, F.C., Willis, N.D., McCallum, I., Shivappa, N., Wirth, M., Hébert, J., Kocaadam, B., Özturan, A., Kelly, S., Bradburn, D.M., Belshaw, N.J., Johnson, I.T., Mathers, J.C.

“…The WNT signalling pathway is involved in the maintenance of homeostasis within the large bowel through the regulation of physiological processes, such as cell…”
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Methylation of the ESR1 CpG island in the colorectal mucosa is an 'all or nothing' process in healthy human colon, and is accelerated by dietary folate supplementation in the mouse by Belshaw, N J, Elliott, G O, Williams, E A, Mathers, J C, Buckley, L, Bahari, B, Johnson, I T

“…ESR1 is frequently silenced by CGI (CpG island) methylation, both in human colorectal tumours and, in an age-dependent manner, in healthy mucosa. It is not…”
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Use of a histone H4 promoter to drive the expression of homologous and heterologous proteins by Penicillium funiculosum by BELSHAW, N. J, HAIGH, N. P, FISH, N. M, ARCHER, D. B, ALCOCER, M. J. C

“…Two genes encoding histone H4 (H4.1 and H4.2) from Penicillium funiculosum have been cloned and characterised. Structurally, the histone H4.1 gene is…”
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O-glycosylation in Aspergillus glucoamylase. Conformation and role in binding by Williamson, G, Belshaw, N.J, Williamson, M.P

“…Functional peptides have been produced by proteolysis of glucoamylase (glucan 1,4-alpha-glucosidase: EC 3.2.1.3) from Aspergillus niger and purified by…”
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Differences in the expression of microRNAs implicated in colorectal carcinogenesis and involved in the WNT signalling pathway in the macroscopically-normal epithelium of people at higher-risk of colorectal cancer by Malcomson, F. C., Willis, N. D., McCallum, I., Xie, L., Kelly, S., Bradburn, M., Belshaw, N. J., Johnson, I. T., Mathers, J. C.

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Anti-neoplastic effects of non-digestible carbohydrates on Wnt signalling pathway gene expression and its functional outcomes in the large bowel: a human dietary intervention study by Malcomson, F., Willis, N. D., McCallum, I., Xie, L., Leung, W., Kelly, S. B., Bradburn, M., Belshaw, N. J., Johnson, I. T., Mathers, J. C.

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The procyanidin-mediated induction of apoptosis and cell-cycle arrest in esophageal adenocarcinoma cells is not dependent on p21(Cip1/WAF1) by Pierini, R, Kroon, P A, Guyot, S, Johnson, I T, Belshaw, N J

“…Previous studies have shown that the proanthocyanidin-mediated induction of apoptosis and arrest of the cell cycle in cancer cells was associated with…”
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Impact of non-digestible carbohydrates on biomarkers of gastrointestinal health: a human intervention study by Willis, N. D., Mann, S., Xie, L., McCallum, I. D. J., Kelly, S. B., Bradburn, D. M., Belshaw, N. J., Johnson, I. T., Mathers, J. C.

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MicroRNA expression in the macroscopically-normal epithelium of people at differential risk of colorectal cancer by Malcomson, F., Portilla, M., Willis, N., McCallum, I., Xie, L., Kelly, S., Bradburn, M., Belshaw, N. J., Johnson, I. T., Mathers, J. C.

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Anti-neoplastic effects of non-digestible carbohydrates on WNT signalling in the bowel: a randomised controlled dietary intervention by Malcomson, F., Willis, N., McCallum, I., Xie, L., Leung, W., Kelly, S., Bradburn, M., Belshaw, N. J., Johnson, I. T., Mathers, J. C.

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Impact of age, nutrition and metabolic factors on methylation status of CpG islands in Wnt-related genes of the human colon by Belshaw, N. J., Tapp, H., Bradburn, D. M., Commane, D. M., Arasaradnam, R., Mathers, J. C., Johnson, I. T.

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Production and purification of a granular-starch-binding domain of glucoamylase 1 from Aspergillus niger by Belshaw, Nigel J., Williamson, Gary

“…A domain of glucoamylase 1 from Aspergillus niger which binds to granular starch was produced by proteolytic digestion and purified to apparent homogeneity by…”
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Specificity of the binding domain of glucoamylase 1 by Belshaw, N.J. (AFRC Institute of Food Research, Norwich, England), Williamson, G

“…Glucoamylase 1 from Aspergillus niger hydrolyses granular starch at an increased rate due to the presence of a C-terminal starch-binding domain. This domain…”
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A family 11 xylanase from Penicillium funiculosum is strongly inhibited by three wheat xylanase inhibitors by Furniss, Caroline S.M, Belshaw, Nigel J, Alcocer, Marcos J.C, Williamson, Gary, Elliott, Giles O, Gebruers, Kurt, Haigh, Nigel P, Fish, Neville M, Kroon, Paul A

“…Steady-state kinetic approaches were used to investigate the binding of a novel Penicillium funiculosum xylanase, XYNC, with three known xylanase inhibitor…”
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O-glycosylation and stability : unfolding of glucoamylase induced by heat and guanidine hydrochloride by WILLIAMSON, G, BELSHAW, N. J, NOEL, T. R, RING, S. G, WILLIAMSON, M. P

“…We have examined the stabilities of the catalytic and binding domains of glucoamylase 1 from Aspergillus niger and how these stabilities are affected by the…”
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effect of cadaverine on the formation of anabasine from lysine in hairy root cultures of Nicotiana hesperis by Walton, N.J, Belshaw, N.J

“…Unlabelled cadaverine did not diminish the incorporation into anabasine of (14)C from L-[U-(14)C] lysine supplied to hairy root cultures of Nicotiana nesperis,…”
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A modular esterase from Penicillium funiculosum which releases ferulic acid from plant cell walls and binds crystalline cellulose contains a carbohydrate binding module by Kroon, Paul A., Williamson, Gary, Fish, Neville M., Archer, David B., Belshaw, Nigel J.

“…An esterase was isolated from cultures of the filamentous fungus Penicillium funiculosum grown on sugar beet pulp as the sole carbon source. The enzyme…”
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