Search Results - "Belova, Galina"
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Micro-environment causes reversible changes in DNA methylation and mRNA expression profiles in patient-derived glioma stem cells
Published in PloS one (01-04-2014)“…In vitro and in vivo models are widely used in cancer research. Characterizing the similarities and differences between a patient's tumor and corresponding in…”
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2
Detailed longitudinal sampling of glioma stem cells in situ reveals Chr7 gain and Chr10 loss as repeated events in primary tumor formation and recurrence
Published in International journal of cancer (15-11-2017)“…Intratumoral heterogeneity at the genetic, epigenetic, transcriptomic, and morphologic levels is a commonly observed phenomenon in many aggressive cancer…”
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3
Wip1 Directly Dephosphorylates γ-H2AX and Attenuates the DNA Damage Response
Published in Cancer research (Chicago, Ill.) (15-05-2010)“…The integrity of DNA is constantly challenged throughout the life of a cell by both endogenous and exogenous stresses. A well-organized rapid damage response…”
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4
Effect of Brain- and Tumor-Derived Connective Tissue Growth Factor on Glioma Invasion
Published in JNCI : Journal of the National Cancer Institute (03-08-2011)“…Background Tumor cell invasion is the principal cause of treatment failure and death among patients with malignant gliomas. Connective tissue growth factor…”
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5
Identification of molecular pathways facilitating glioma cell invasion in situ
Published in PloS one (03-11-2014)“…Gliomas are mostly incurable secondary to their diffuse infiltrative nature. Thus, specific therapeutic targeting of invasive glioma cells is an attractive…”
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6
Undiagnosed RASopathies in infertile men
Published in Frontiers in endocrinology (Lausanne) (09-04-2024)“…RASopathies are syndromes caused by congenital defects in the Ras/mitogen-activated protein kinase (MAPK) pathway genes, with a population prevalence of 1 in…”
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7
The Complete Genome of Hyperthermophile Methanopyrus kandleri AV19 and Monophyly of Archaeal Methanogens
Published in Proceedings of the National Academy of Sciences - PNAS (02-04-2002)“…We have determined the complete 1,694,969-nt sequence of the GC-rich genome of Methanopyrus kandleri by using a whole direct genome sequencing approach. This…”
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8
Self-propagating high-temperature synthesis of AlN–TiC powder composition using sodium azide and C2F4 fluoroplastic
Published in Frontier Materials & Technologies (30-09-2024)“…Producing powder compositions using conventional processing technology can lead to the formation of large agglomerates and, therefore, makes it difficult to…”
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9
Chromosomal Protein HMGN1 Enhances the Heat Shock-induced Remodeling of Hsp70 Chromatin
Published in The Journal of biological chemistry (28-03-2008)“…The nucleosome-binding protein HMGN1 affects the structure and function of chromatin; however, its role in regulating specific gene expression in living cells…”
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10
Histone demethylase Jumonji D3 (JMJD3) as a tumor suppressor by regulating p53 protein nuclear stabilization
Published in PloS one (07-12-2012)“…Histone methylation regulates normal stem cell fate decisions through a coordinated interplay between histone methyltransferases and demethylases at lineage…”
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11
The autoimmune suppressor Gadd45α inhibits the T cell alternative p38 activation pathway
Published in Nature immunology (01-04-2005)“…The p38 MAP kinase (MAPK) is phosphorylated and activated by upstream MAPK kinases. T cells have an alternative pathway in which T cell receptor-activated…”
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12
Chemical inhibition of Wip1 phosphatase contributes to suppression of tumorigenesis
Published in Cancer biology & therapy (01-10-2005)“…Wip1 is an amplified oncogene whose deletion causes a tumor resistant phenotype in mice. These observations provide justification for a search for Wip1…”
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13
Gadd45a regulates matrix metalloproteinases by suppressing ΔNp63α and β-catenin via p38 MAP kinase and APC complex activation
Published in Oncogene (11-03-2004)“…The p53-regulated growth arrest and DNA damage-inducible gene product Gadd45a has been recently identified as a key factor protecting the epidermis against…”
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14
Helix-Hairpin-Helix Motifs Confer Salt Resistance and Processivity on Chimeric DNA Polymerases
Published in Proceedings of the National Academy of Sciences - PNAS (15-10-2002)“…Helix-hairpin-helix (HhH) is a widespread motif involved in sequence-nonspecific DNA binding. The majority of HhH motifs function as DNA-binding modules with…”
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15
Chromosomal Protein HMGN1 Modulates the Phosphorylation of Serine 1 in Histone H2A
Published in Biochemistry (Easton) (19-12-2006)“…Here we demonstrate that HMGN1, a nuclear protein that binds specifically to nucleosomes, modulates the level of histone H2A phosphorylation. In Hmgn1- / -…”
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16
The Domain Organization and Properties of Individual Domains of DNA Topoisomerase V, a Type 1B Topoisomerase with DNA Repair Activities
Published in The Journal of biological chemistry (15-02-2002)“…Topoisomerase V (Topo V) is a type IB (eukaryotic-like) DNA topoisomerase. It was discovered in the hyperthermophilic prokaryote Methanopyrus kandleri and is…”
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17
A Type IB Topoisomerase with DNA Repair Activities
Published in Proceedings of the National Academy of Sciences - PNAS (22-05-2001)“…Previously we have characterized type IB DNA topoisomerase V (topo V) in the hyperthermophile Methanopyrus kandleri. The enzyme has a powerful topoisomerase…”
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18
A Core Regulatory Circuit in Glioblastoma Stem Cells Links MAPK Activation to a Transcriptional Program of Neural Stem Cell Identity
Published in Scientific reports (03-03-2017)“…Glioblastoma, the most common primary malignant brain tumor, harbors a small population of tumor initiating cells (glioblastoma stem cells) that have many…”
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19
Histone Demethylase Jumonji D3
Published in PloS one (07-12-2012)“…Histone methylation regulates normal stem cell fate decisions through a coordinated interplay between histone methyltransferases and demethylases at lineage…”
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Journal Article -
20
Chromosomal Protein HMGN1 Enhances the Heat Shock-induced Remodeling of Hsp70 Chromatins
Published in The Journal of biological chemistry (24-01-2008)“…The nucleosome-binding protein HMGN1 affects the structure and function of chromatin; however, its role in regulating specific gene expression in living cells…”
Get full text
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