Search Results - "Belousov, Andrei B."

Neuronal gap junction coupling is regulated by glutamate and plays critical role in cell death during neuronal injury by Wang, Yongfu, Song, Ji-Hoon, Denisova, Janna V, Park, Won-Mee, Fontes, Joseph D, Belousov, Andrei B

“…In the mammalian CNS, excessive release of glutamate and overactivation of glutamate receptors are responsible for the secondary (delayed) neuronal death…”
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Neuronal gap junctions are required for NMDA receptor-mediated excitotoxicity: implications in ischemic stroke by Wang, Yongfu, Denisova, Janna V, Kang, Ki Sung, Fontes, Joseph D, Zhu, Bao Ting, Belousov, Andrei B

“…N-methyl-D-aspartate receptors (NMDARs) play an important role in cell survival versus cell death decisions during neuronal development, ischemia, trauma, and…”
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Interplay of chemical neurotransmitters regulates developmental increase in electrical synapses by Park, Won-Mee, Wang, Yongfu, Park, Soodong, Denisova, Janna V, Fontes, Joseph D, Belousov, Andrei B

“…Coupling of neurons by electrical synapses (gap junctions) transiently increases in the mammalian CNS during development. We report here that the developmental…”
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Death of Neurons following Injury Requires Conductive Neuronal Gap Junction Channels but Not a Specific Connexin by Fontes, Joseph D, Ramsey, Jon, Polk, Jeremy M, Koop, Andre, Denisova, Janna V, Belousov, Andrei B

“…Pharmacological blockade or genetic knockout of neuronal connexin 36 (Cx36)-containing gap junctions reduces neuronal death caused by ischemia, traumatic brain…”
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Neuronal gap junctions play a role in the secondary neuronal death following controlled cortical impact by Belousov, Andrei B., Wang, Yongfu, Song, Ji-Hoon, Denisova, Janna V., Berman, Nancy E., Fontes, Joseph D.

“…► Controlled cortical impact in mice induces secondary neuronal death in the striatum. ► This neuronal death is reduced by blockade of neuronal gap junctions…”
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The regulation and role of neuronal gap junctions during neuronal injury by Belousov, Andrei B.

“…In the mammalian CNS, excessive release of glutamate and overactivation of glutamate receptors are responsible for the secondary (delayed) neuronal death…”
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Presynaptic and Postsynaptic Actions and Modulation of Neuroendocrine Neurons by a New Hypothalamic Peptide, Hypocretin/Orexin by van den Pol, Anthony N, Gao, Xiao-Bing, Obrietan, Karl, Kilduff, Thomas S, Belousov, Andrei B

“…A new orexigenic peptide called hypocretin (orexin) has recently been described in neurons of the lateral hypothalamus and perifornical area. The medial and…”
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Regulation of connexin 36 expression during development by Song, Ji-Hoon, Wang, Yongfu, Fontes, Joseph D., Belousov, Andrei B.

“…► Acute activation of group II mGluRs or ischemia both increase Cx36 protein expression. ► The regulation likely is due to new protein synthesis. ► Thus, the…”
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Neuronal gap junctions: making and breaking connections during development and injury by Belousov, Andrei B, Fontes, Joseph D

“…In the mammalian central nervous system (CNS), coupling of neurons by gap junctions (i.e., electrical synapses) and the expression of the neuronal gap junction…”
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The regulation and role of neuronal gap junctions during development by Belousov, Andrei B.

“…Coupling of neurons by electrical synapses (gap junctions) transiently increases in the mammalian CNS during development and plays a role in a number of…”
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Role of neuronal gap junctions in NMDA receptor-mediated excitotoxicity and ischemic neuronal death by Belousov, Andrei, Fontes, Joseph

“…In the mammalian central nervous system（CNS）coupling of neurons by gap junctions and the expression of neuronal gap junction protein,connexin 36（Cx36）rapidly…”
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Novel model for the mechanisms of glutamate-dependent excitotoxicity: Role of neuronal gap junctions by Belousov, Andrei B

“…Abstract In the mammalian central nervous system (CNS), coupling of neurons by gap junctions (electrical synapses) increases during early post-natal…”
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Gap junctions and hemichannels: communicating cell death in neurodevelopment and disease by Belousov, Andrei B, Fontes, Joseph D, Freitas-Andrade, Moises, Naus, Christian C

“…Gap junctions are unique membrane channels that play a significant role in intercellular communication in the developing and mature central nervous system…”
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Recovery of network-driven glutamatergic activity in rat hippocampal neurons during chronic glutamate receptor blockade by Leininger, Eric, Belousov, Andrei B

“…Abstract Previous studies indicated that a long-term decrease in the activity of ionotropic glutamate receptors induces cholinergic activity in rat and mouse…”
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Deletion of neuronal gap junction protein connexin 36 impairs hippocampal LTP by Wang, Yongfu, Belousov, Andrei B.

“…► Genetic deletion of neuronal Cx36 causes learning and memory deficiencies. ► Here we tested whether genetic deletion of Cx36 affects hippocampal LTP. ► We…”
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A potential role for neuronal connexin 36 in the pathogenesis of amyotrophic lateral sclerosis by Belousov, Andrei B., Nishimune, Hiroshi, Denisova, Janna V., Fontes, Joseph D.

“…•A role for neuronal connexin 36 in the pathogenesis of ALS is proposed.•The mechanism relies on contribution of connexin 36 to ALS-related neuronal death.•A…”
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Neuronal gap junction coupling as the primary determinant of the extent of glutamate-mediated excitotoxicity by Belousov, Andrei B., Fontes, Joseph D.

“…In the mammalian central nervous system (CNS), coupling of neurons by gap junctions (electrical synapses) increases during early postnatal development, then…”
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Transgenic Expression of Glud1 (Glutamate Dehydrogenase 1) in Neurons: In Vivo Model of Enhanced Glutamate Release, Altered Synaptic Plasticity, and Selective Neuronal Vulnerability by Bao, Xiaodong, Pal, Ranu, Hascup, Kevin N, Wang, Yongfu, Wang, Wen-Tung, Xu, Wenhao, Hui, Dongwei, Agbas, Abdulbaki, Wang, Xinkun, Michaelis, Mary L, Choi, In-Young, Belousov, Andrei B, Gerhardt, Greg A, Michaelis, Elias K

“…The effects of lifelong, moderate excess release of glutamate (Glu) in the CNS have not been previously characterized. We created a transgenic (Tg) mouse model…”
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Calcium-Dependent Regulation of Cholinergic Cell Phenotype in the Hypothalamus In Vitro by Belousov, Andrei B, Hunt, Nicole D, Raju, Ryan P, Denisova, Janna V

“…Department of Cell and Molecular Biology, Tulane University, New Orleans, Louisiana 70118 Belousov, Andrei B., Nicole D. Hunt, Ryan P. Raju, and Janna V…”
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NMDA receptors regulate developmental gap junction uncoupling via CREB signaling by Belousov, Andrei B, Arumugam, Harsha, Liu, Xinhuai, Colombo, Paul J, Corriveau, Roderick A

“…Signaling through gap junctions (electrical synapses) is important in the development of the mammalian central nervous system. Abundant between neurons during…”
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