Search Results - "Belonga, Kenneth L."

Asymmetric Synthesis of 2,6-Methylated Piperazines by Mickelson, John W, Belonga, Kenneth L, Jacobsen, E. Jon

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High-Affinity Partial Agonist Imidazo[1,5-a]quinoxaline Amides, Carbamates, and Ureas at the γ-Aminobutyric Acid A/Benzodiazepine Receptor Complex by Jacobsen, E. Jon, TenBrink, Ruth E, Stelzer, Lindsay S, Belonga, Kenneth L, Carter, Donald B, Im, Haesook K, Im, Wha Bin, Sethy, Vimala H, Tang, Andy H, VonVoigtlander, Philip F, Petke, James D

“…A series of imidazo[1,5-a]quinoxaline amides, carbamates, and ureas which have high affinity for the γ-aminobutyric acid A/benzodiazepine receptor complex was…”
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Synthesis of Novel 2,4-Diaminopyrrolo[2,3-d]pyrimidines with Antioxidant, Neuroprotective, and Antiasthma Activity by Bundy, Gordon L, Ayer, Donald E, Banitt, Lee S, Belonga, Kenneth L, Mizsak, Stephen A, Palmer, John R, Tustin, James M, Chin, Jia En, Hall, Edward D

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Novel 21-aminosteroids that inhibit iron-dependent lipid peroxidation and protect against central nervous system trauma by Jacobsen, E. Jon, McCall, John M, Ayer, Donald E, VanDoornik, Fred J, Palmer, John R, Belonga, Kenneth L, Braughler, J. Mark, Hall, Edward D, Houser, David J

“…A novel class of 21-aminosteroids has been developed. Compounds within this series are potent inhibitors of iron-dependent lipid peroxidation in rat brain…”
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2-(Aminomethyl)chromans that inhibit iron-dependent lipid peroxidation and protect against central nervous system trauma and ischemia by Jacobsen, E. Jon, VanDoornik, Fred J, Ayer, Donald E, Belonga, Kenneth L, Braughler, J. Mark, Hall, Edward D, Houser, David J

“…A series of 2-(aminomethyl)chromans was developed as potent inhibitors of iron-dependent lipid peroxidation. Compounds within this class are extremely…”
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Piperazine Imidazo[1,5-a]quinoxaline Ureas as High-Affinity GABAA Ligands of Dual Functionality by Jacobsen, E. Jon, Stelzer, Lindsay S, TenBrink, Ruth E, Belonga, Kenneth L, Carter, Donald B, Im, Haesook K, Im, Wha Bin, Sethy, Vimala H, Tang, Andy H, VonVoigtlander, Philip F, Petke, James D, Zhong, Wei-Zhu, Mickelson, John W

“…A series of imidazo[1,5-a]quinoxaline piperazine ureas appended with a tert-butyl ester side chain at the 3-position was developed. Analogues within this…”
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3-Phenyl-Substituted Imidazo[1,5-a]quinoxalin-4-ones and Imidazo[1,5-a]quinoxaline Ureas That Have High Affinity at the GABAA/Benzodiazepine Receptor Complex by Jacobsen, E. Jon, Stelzer, Lindsay S, Belonga, Kenneth L, Carter, Donald B, Im, Wha Bin, Sethy, Vimala H, Tang, Andrew H, VonVoigtlander, Philip F, Petke, James D

“…A series of imidazo[1,5-a]quinoxalin-4-ones and imidazo[1,5-a]quinoxaline ureas containing substituted phenyl groups at the 3-position was developed. Compounds…”
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Piperazine Imidazo[1,5- a ]quinoxaline Ureas as High-Affinity GABA A Ligands of Dual Functionality by Jacobsen, E. Jon, Stelzer, Lindsay S., TenBrink, Ruth E., Belonga, Kenneth L., Carter, Donald B., Im, Haesook K., Im, Wha Bin, Sethy, Vimala H., Tang, Andy H., VonVoigtlander, Philip F., Petke, James D., Zhong, Wei-Zhu, Mickelson, John W.

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3-Phenyl-Substituted Imidazo[1,5- a ]quinoxalin-4-ones and Imidazo[1,5- a ]quinoxaline Ureas That Have High Affinity at the GABA A /Benzodiazepine Receptor Complex by Jacobsen, E. Jon, Stelzer, Lindsay S., Belonga, Kenneth L., Carter, Donald B., Im, Wha Bin, Sethy, Vimala H., Tang, Andrew H., VonVoigtlander, Philip F., Petke, James D.

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Synthesis of a Series of Stromelysin-Selective Thiadiazole Urea Matrix Metalloproteinase Inhibitors by Jacobsen, E. Jon, Mitchell, Mark A, Hendges, Susan K, Belonga, Kenneth L, Skaletzky, Louis L, Stelzer, Lindsay S, Lindberg, Thomas. J, Fritzen, Edward L, Schostarez, Heinrich J, O'Sullivan, Theresa J, Maggiora, Linda L, Stuchly, Christopher W, Laborde, Alice L, Kubicek, Marc F, Poorman, Roger A, Beck, Joan M, Miller, Henry R, Petzold, Gary L, Scott, Pam S, Truesdell, Scott E, Wallace, Tanya L, Wilks, John W, Fisher, Christopher, Goodman, Linda V, Kaytes, Paul S, Ledbetter, Stephen R, Powers, Elaine A, Vogeli, Gabriel, Mott, John E, Trepod, Catherine M, Staples, Douglas J, Baldwin, Eric T, Finzel, Barry C

“…The synthesis and enzyme inhibition data for a series of thiadiazole urea matrix metalloproteinase (MMP) inhibitors are described. A broad screening effort was…”
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Solution structures of stromelysin complexed to thiadiazole inhibitors by Stockman, Brian J., Waldon, Daniel J., Gates, Jo A., Scahill, Terrence A., Kloosterman, David A., Mizsak, Stephen A., Jacobsen, E. Jon, Belonga, Kenneth L., Mitchell, Mark A., Mao, Boryeu, Petke, James D., Goodman, Linda, Powers, Elaine A., Ledbetter, Steven R., Kaytes, Paul S., Vogeli, Gabriel, Marshall, Vincent P., Petzold, Gary L., Poorman, Roger A.

“…Unregulated or overexpressed matrix metalloproteinases (MMPs), including stromelysin, collagenase, and gelatinase, have been implicated in several pathological…”
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