Search Results - "Belone, Andrea"
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Emergence and Transmission of Drug-/Multidrug-resistant Mycobacterium leprae in a Former Leprosy Colony in the Brazilian Amazon
Published in Clinical infectious diseases (06-05-2020)“…Leprosy has been treated with multidrug therapy, which has been distributed for free across the globe and regarded as highly efficient. However, the…”
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A genome wide association study identifies a lncRna as risk factor for pathological inflammatory responses in leprosy
Published in PLoS genetics (21-02-2017)“…Leprosy Type-1 Reactions (T1Rs) are pathological inflammatory responses that afflict a sub-group of leprosy patients and result in peripheral nerve damage…”
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Multidrug Therapy for Leprosy Can Cure Patients with Lobomycosis in Acre State, Brazil: A Proof of Therapy Study
Published in The American journal of tropical medicine and hygiene (01-02-2021)“…Lobomycosis, also referred to as lacaziosis, is an endemic cutaneous and subcutaneous fungal disease that mainly affects Amazonian forest dwellers in Brazil…”
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qPCR detection of Mycobacterium leprae in biopsies and slit skin smear of different leprosy clinical forms
Published in The Brazilian journal of infectious diseases (01-01-2017)“…Leprosy, whose etiological agent is Mycobacterium leprae, is a chronic infectious disease that mainly affects the skin and peripheral nervous system. The…”
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Analysis of Immune Response Markers in Jorge Lobo's Disease Lesions Suggests the Occurrence of Mixed T Helper Responses with the Dominance of Regulatory T Cell Activity
Published in PloS one (23-12-2015)“…Jorge Lobo's disease (JLD) is a chronic infection that affects the skin and subcutaneous tissues. Its etiologic agent is the fungus Lacazia loboi. Lesions are…”
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Whole blood transcriptomics reveals the enrichment of neutrophil activation pathways during erythema nodosum leprosum reaction
Published in Frontiers in immunology (23-04-2024)“…Patients with the multibacillary form of leprosy can develop reactional episodes of acute inflammation, known as erythema nodosum leprosum (ENL), which are…”
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Differential Expression of MicroRNAs in Leprosy Skin Lesions
Published in Frontiers in immunology (25-08-2017)“…Leprosy, a chronic infectious disease caused by , is a major public health problem in poor and developing countries of the Americas, Africa, and Asia…”
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Polymorphisms in the TGFB1 and IL2RA genes are associated with clinical forms of leprosy in Brazilian population
Published in Memórias do Instituto Oswaldo Cruz (10-12-2018)“…BACKGROUND Leprosy is a chronic infectious disease caused by Mycobacterium leprae, and compromises the skin and peripheral nerves. This disease has been…”
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Serodiagnosis of leprosy and follow-up of household contacts using a commercial rapid test containing ND-O/LID-1 antigens
Published in Leprosy review (01-06-2017)“…Introduction: Early diagnosis of leprosy, including the diagnosis of sub-clinical disease in contacts of known cases, would be a major advance. The signs of…”
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Simultaneous analysis of multiple T helper subsets in leprosy reveals distinct patterns of Th1, Th2, Th17 and Tregs markers expression in clinical forms and reactional events
Published in Medical microbiology and immunology (01-12-2017)“…Leprosy is a chronic infectious disease caused by Mycobacterium leprae . Previous studies have demonstrated that the difference among clinical forms of leprosy…”
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Association of TNFSF8 Regulatory Variants With Excessive Inflammatory Responses but not Leprosy Per Se
Published in The Journal of infectious diseases (15-03-2015)“…Background. Type 1 reactions (TIR) affect a considerable proportion of patients with leprosy. In those with TIR, the host immune response pathologically…”
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Molecular Drug Susceptibility Testing and Genotyping of Mycobacterium leprae Strains from South America
Published in Antimicrobial Agents and Chemotherapy (01-06-2011)“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Immunohistochemical assessment of cell populations in leprosy-spectrum lesions and reactional forms
Published in Histology and histopathology (01-04-2017)“…In situ immunophenotyping of leprosy lesions can improve our understanding of the biology of inflammatory cells during the immune response to Mycobacterium…”
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Use of Sera from Humans and Dolphins with Lacaziosis and Sera from Experimentally Infected Mice for Western Blot Analyses of Lacazia loboi Antigens
Published in Clinical and Vaccine Immunology (01-01-2008)“…Classifications Services CVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Potential of AKR1B10 as a Biomarker and Therapeutic Target in Type 2 Leprosy Reaction
Published in Frontiers in medicine (24-09-2018)“…The (aldo-keto reductase family 1 member B10) gene has important functions in carcinogen-induced neoplasia. AKR1B10 is also expressed in type 2 reaction…”
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Lobomycosis Epidemiology and Management: The Quest for a Cure for the Most Neglected of Neglected Tropical Diseases
Published in Journal of fungi (Basel) (10-05-2022)“…Lobomycosis is a chronic disease caused by , which is endemic to the Amazon rainforest, where it affects forest dwellers in Brazil. There is no disease control…”
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Genome-Wide Screening of mRNA Expression in Leprosy Patients
Published in Frontiers in genetics (20-11-2015)“…Leprosy, an infectious disease caused by Mycobacterium leprae, affects millions of people worldwide. However, little is known regarding its molecular…”
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Prediction of the occurrence of leprosy reactions based on Bayesian networks
Published in Frontiers in medicine (26-07-2023)“…Leprosy reactions (LR) are severe episodes of intense activation of the host inflammatory response of uncertain etiology, today the leading cause of permanent…”
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Mycobacterium leprae in ocular tissues: Histopathological findings in experimental leprosy
Published in Indian journal of dermatology, venereology, and leprology (01-03-2011)“…Leprosy is disease of systemic manifestations with a high level of ocular complications. [1] Inside the eyes, the anterior segment is the most common area…”
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