Search Results - "Belmonte, Beatrice"
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WNT signaling modulates PD-L1 expression in the stem cell compartment of triple-negative breast cancer
Published in Oncogene (01-05-2019)“…Triple-negative breast cancers (TNBCs) are characterized by a poor prognosis and lack of targeted treatments, and thus, new therapeutic strategies are urgently…”
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2
Genetic and Epigenetic Factors of Takotsubo Syndrome: A Systematic Review
Published in International journal of molecular sciences (13-09-2021)“…Takotsubo syndrome (TTS), recognized as stress's cardiomyopathy, or as left ventricular apical balloon syndrome in recent years, is a rare pathology, described…”
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3
miRNA Regulation of Cell Phenotype and Parietal Remodeling in Atherosclerotic and Non-Atherosclerotic Aortic Aneurysms: Differences and Similarities
Published in International journal of molecular sciences (24-02-2024)“…Aortic aneurysms are a serious health concern as their rupture leads to high morbidity and mortality. Abdominal aortic aneurysms (AAAs) and thoracic aortic…”
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4
Prognostic Implications of the Complement Protein C1q in Gliomas
Published in Frontiers in immunology (10-10-2019)“…The contribution of the complement system in the pathophysiology of brain cancers has been recently considered in light of its well-known involvement in…”
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5
The Ferroxidase Hephaestin in Lung Cancer: Pathological Significance and Prognostic Value
Published in Frontiers in oncology (19-05-2021)“…Hephaestin (HEPH) belongs to a group of exocytoplasmic ferroxidases which contribute to cellular iron homeostasis by favouring its export. Down-regulation of…”
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6
Pathogenic Role of Complement in Antiphospholipid Syndrome and Therapeutic Implications
Published in Frontiers in immunology (19-06-2018)“…Antiphospholipid syndrome (APS) is an acquired autoimmune disease characterized by thromboembolic events, pregnancy morbidity, and the presence of…”
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PARP-1, EpCAM, and FRα as potential targets for intraoperative detection and delineation of endometriosis: a quantitative tissue expression analysis
Published in Reproductive biology and endocrinology (31-07-2024)“…Endometriosis is a gynecological disease characterized by the presence of endometrial tissue in abnormal locations, leading to severe symptoms, inflammation,…”
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Is the Complement Protein C1q a Pro- or Anti-tumorigenic Factor? Bioinformatics Analysis Involving Human Carcinomas
Published in Frontiers in immunology (03-05-2019)“…C1q is the first subcomponent of the classical pathway of the complement system and belongs to the C1q/Tumor Necrosis Factor superfamily. C1q can perform a…”
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Nonsense codons suppression. An acute toxicity study of three optimized TRIDs in murine model, safety and tolerability evaluation
Published in Biomedicine & pharmacotherapy (01-12-2022)“…Stop mutations cause 11% of the genetic diseases, due to the introduction of a premature termination codon (PTC) in the mRNA, followed by the production of a…”
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10
Complement Protein C1q Binds to Hyaluronic Acid in the Malignant Pleural Mesothelioma Microenvironment and Promotes Tumor Growth
Published in Frontiers in immunology (20-11-2017)“…C1q is the first recognition subcomponent of the complement classical pathway, which acts toward the clearance of pathogens and apoptotic cells. C1q is also…”
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Distinct Roles of Classical and Lectin Pathways of Complement in Preeclamptic Placentae
Published in Frontiers in immunology (31-05-2022)“…Pre-eclampsia is a pregnancy complication characterized by defective vascular remodeling in maternal decidua responsible for reduced blood flow leading to…”
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12
The Inflammatory Feed-Forward Loop Triggered by the Complement Component C3 as a Potential Target in Endometriosis
Published in Frontiers in immunology (13-08-2021)“…The complement system is a major component of humoral innate immunity, acting as a first line of defense against microbes opsonization and lysis of pathogens…”
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13
Prognostic Value of Complement Properdin in Cancer
Published in Frontiers in immunology (19-01-2021)“…The complement system is readily triggered by the presence of damage-associated molecular patterns on the surface of tumor cells. The complement alternative…”
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14
The PDGFRβ/ERK1/2 pathway regulates CDCP1 expression in triple-negative breast cancer
Published in BMC cancer (23-05-2018)“…CDCP1, a transmembrane protein with tumor pro-metastatic activity, was recently identified as a prognostic marker in TNBC, the most aggressive breast cancer…”
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15
Iatrogenic Sigma Perforation in a Patient with Localized Rectal and Sigma AL Amyloidosis: A Forensic Case and a Literature Review
Published in Forensic sciences (Basel, Switzerland) (13-09-2024)“…Amyloidosis is defined as a rare group of 30 protein-folding diseases characterized by the extracellular deposition of a specific soluble precursor protein…”
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16
Protective and regenerative effects of a novel medical device against esophageal mucosal damage using in vitro and ex vivo models
Published in Biomedicine & pharmacotherapy (01-11-2020)“…[Display omitted] Gastroesophageal reflux disease (GERD) is a common digestive disorder that causes esophagitis and injuries to the esophageal mucosa. GERD…”
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17
Cross-Talk between Myeloid-Derived Suppressor Cells and Mast Cells Mediates Tumor-Specific Immunosuppression in Prostate Cancer
Published in Cancer immunology research (01-05-2018)“…Immunotherapy, including the use of checkpoint inhibitors, is a potent therapeutic approach for some cancers, but has limited success with prostate tumors, in…”
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18
A longitudinal study of C1q and anti-C1q autoantibodies in homologous and heterologous pregnancies for predicting pre-eclampsia
Published in Frontiers in immunology (09-11-2022)“…C1q, the recognition molecule of the classical pathway of the complement system, plays a central role in pregnancy. Lack of C1q is characterized by poor…”
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Stromal and Immune Cell Dynamics in Tumor Associated Tertiary Lymphoid Structures and Anti-Tumor Immune Responses
Published in Frontiers in cell and developmental biology (08-07-2022)“…Tertiary lymphoid structures (TLS) are ectopic lymphoid organs that have been observed in chronic inflammatory conditions including cancer, where they are…”
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20
Hyaluronic Acid Present in the Tumor Microenvironment Can Negate the Pro-apototic Effect of a Recombinant Fragment of Human Surfactant Protein D on Breast Cancer Cells
Published in Frontiers in immunology (08-07-2020)“…Human surfactant protein D (SP-D) belongs to the family of collectins that is composed of a characteristic amino-terminal collagenous region and a…”
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