Search Results - "Bellvé, Karl D"

Dopamine transporter endocytic trafficking in striatal dopaminergic neurons: differential dependence on dynamin and the actin cytoskeleton by Gabriel, Luke R, Wu, Sijia, Kearney, Patrick, Bellvé, Karl D, Standley, Clive, Fogarty, Kevin E, Melikian, Haley E

“…Dopaminergic signaling profoundly impacts rewarding behaviors, movement, and executive function. The presynaptic dopamine (DA) transporter (DAT) recaptures…”
Get full text

NPHP4 controls ciliary trafficking of membrane proteins and large soluble proteins at the transition zone by Awata, Junya, Takada, Saeko, Standley, Clive, Lechtreck, Karl F, Bellvé, Karl D, Pazour, Gregory J, Fogarty, Kevin E, Witman, George B

“…The protein nephrocystin-4 (NPHP4) is widespread in ciliated organisms, and defects in NPHP4 cause nephronophthisis and blindness in humans. To learn more…”
Get full text

Rabenosyn-5 defines the fate of the transferrin receptor following clathrin-mediated endocytosis by Navaroli, Deanna M, Bellvé, Karl D, Standley, Clive, Lifshitz, Lawrence M, Cardia, James, Lambright, David, Leonard, Deborah, Fogarty, Kevin E, Corvera, Silvia

“…Cell surface receptors and other proteins internalize through diverse mechanisms at the plasma membrane and are sorted to different destinations. Different…”
Get full text

Ack1 is a dopamine transporter endocytic brake that rescues a trafficking-dysregulated ADHD coding variant by Wu, Sijia, Bellve, Karl D., Fogarty, Kevin E., Melikian, Haley E.

“…The dopamine (DA) transporter (DAT) facilitates high-affinity presynaptic DA reuptake that temporally and spatially constrains DA neurotransmission. Aberrant…”
Get full text

Sorting of EGF and transferrin at the plasma membrane and by cargo-specific signaling to EEA1-enriched endosomes by Leonard, Deborah, Hayakawa, Akira, Lawe, Deirdre, Lambright, David, Bellve, Karl D, Standley, Clive, Lifshitz, Lawrence M, Fogarty, Kevin E, Corvera, Silvia

“…The biological function of receptors is determined by their appropriate trafficking through the endosomal pathway. Following internalization, the transferrin…”
Get full text

Insulin Stimulates Membrane Fusion and GLUT4 Accumulation in Clathrin Coats on Adipocyte Plasma Membranes by Huang, Shaohui, Lifshitz, Larry M., Jones, Christine, Bellve, Karl D., Standley, Clive, Fonseca, Sonya, Corvera, Silvia, Fogarty, Kevin E., Czech, Michael P.

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
Get full text

Visualization of self-delivering hydrophobically modified siRNA cellular internalization by Ly, Socheata, Navaroli, Deanna M., Didiot, Marie-Cécile, Cardia, James, Pandarinathan, Lakshmipathi, Alterman, Julia F., Fogarty, Kevin, Standley, Clive, Lifshitz, Lawrence M., Bellve, Karl D., Prot, Matthieu, Echeverria, Dimas, Corvera, Silvia, Khvorova, Anastasia

Get full text

Type 1 ryanodine receptor knock-in mutation causing central core disease of skeletal muscle also displays a neuronal phenotype by De Crescenzo, Valerie, Fogarty, Kevin E, Lefkowitz, Jason J, Bellve, Karl D, Zvaritch, Elena, MacLennan, David H, Walsh, John V. Jr

“…The type 1 ryanodine receptor (RyR1) is expressed widely in the brain, with high levels in the cerebellum, hippocampus, and hypothalamus. We have shown that…”
Get full text

Nephrocystin-4 controls ciliary trafficking of membrane and large soluble proteins at the transition zone by Awata, Junya, Takada, Saeko, Standley, Clive, Lechtreck, Karl F., Bellvé, Karl D., Pazour, Gregory J., Fogarty, Kevin E., Witman, George B.

“…The protein nephrocystin-4 (NPHP4) is widespread in ciliated organisms, and defects in NPHP4 cause nephronophthisis and blindness in humans. To learn more…”
Get full text

Dihydropyridine Receptors and Type 1 Ryanodine Receptors Constitute the Molecular Machinery for Voltage-Induced Ca2+ Release in Nerve Terminals by De Crescenzo, Valerie, Fogarty, Kevin E, ZhuGe, Ronghua, Tuft, Richard A, Lifshitz, Lawrence M, Carmichael, Jeffrey, Bellve, Karl D, Baker, Stephen P, Zissimopoulos, S, Lai, F. Anthony, Lemos, Jose R, Walsh, John V., Jr

“…Ca2+ stores were studied in a preparation of freshly dissociated terminals from hypothalamic magnocellular neurons. Depolarization from a holding level of -80…”
Get full text

Plasma Membrane Domains Specialized for Clathrin-mediated Endocytosis in Primary Cells by Bellve, Karl D., Leonard, Deborah, Standley, Clive, Lifshitz, Lawrence M., Tuft, Richard A., Hayakawa, Akira, Corvera, Silvia, Fogarty, Kevin E.

“…Clathrin assembly at the plasma membrane is a fundamental process required for endocytosis. In cultured cells, most of the clathrin is localized to large…”
Get full text

Visualization of self-delivering hydrophobically modified siRNA cellular internalization by Ly, Socheata, Navaroli, Deanna M, Didiot, Marie-Cécile, Cardia, James, Pandarinathan, Lakshmipathi, Alterman, Julia F, Fogarty, Kevin, Standley, Clive, Lifshitz, Lawrence M, Bellve, Karl D, Prot, Matthieu, Echeverria, Dimas, Corvera, Silvia, Khvorova, Anastasia

“…siRNAs are a new class of therapeutic modalities with promising clinical efficacy that requires modification or formulation for delivery to the tissue and cell…”
Get full text

Human adipose tissue expansion in pregnancy is impaired in gestational diabetes mellitus by Rojas-Rodriguez, Raziel, Lifshitz, Lawrence M., Bellve, Karl D., Min, So Yun, Pires, Jacqueline, Leung, Katherine, Boeras, Crina, Sert, Aylin, Draper, Jacqueline T., Corvera, Silvia, Moore Simas, Tiffany A.

“…Aims/hypothesis During pregnancy, adipose tissue (AT) must expand to support the growing fetus and the future nutritional needs of the offspring. Limited…”
Get full text

Catecholamine exocytosis during low frequency stimulation in mouse adrenal chromaffin cells is primarily asynchronous and controlled by the novel mechanism of Ca2+ syntilla suppression by Lefkowitz, Jason J., DeCrescenzo, Valerie, Duan, Kailai, Bellve, Karl D., Fogarty, Kevin E., Walsh, John V., ZhuGe, Ronghua

“…Key points Although the importance of asynchronous exocytosis is becoming clearer, not enough is known about its roles and mechanisms. Here we describe the…”
Get full text

Adipose tissue angiogenesis assay by Rojas-Rodriguez, Raziel, Gealekman, Olga, Kruse, Maxwell E, Rosenthal, Brittany, Rao, Kishore, Min, Soyun, Bellve, Karl D, Lifshitz, Lawrence M, Corvera, Silvia

“…Changes in adipose tissue mass must be accompanied by parallel changes in microcirculation. Investigating the mechanisms that regulate adipose tissue…”
Get more information

Beclin 1 regulates growth factor receptor signaling in breast cancer by Rohatgi, R A, Janusis, J, Leonard, D, Bellvé, K D, Fogarty, K E, Baehrecke, E H, Corvera, S, Shaw, L M

“…Beclin 1 is a haploinsufficient tumor suppressor that is decreased in many human tumors. The function of beclin 1 in cancer has been attributed primarily to…”
Get full text

Suppression of Ca2+ syntillas increases spontaneous exocytosis in mouse adrenal chromaffin cells by Lefkowitz, Jason J, Fogarty, Kevin E, Lifshitz, Lawrence M, Bellve, Karl D, Tuft, Richard A, ZhuGe, Ronghua, Walsh, Jr, John V, De Crescenzo, Valerie

“…A central concept in the physiology of neurosecretion is that a rise in cytosolic [Ca(2+)] in the vicinity of plasmalemmal Ca(2+) channels due to Ca(2+) influx…”
Get full text

Rabenosyn-5 defines the fate of the transferrin receptor following clathrin-mediated endocytosis by Navaroli, Deanna M., Bellvé, Karl D., Standley, Clive, Lifshitz, Lawrence M., Cardia, James, Lambright, David, Leonard, Deborah, Fogarty, Kevin E., Corvera, Silvia

Get full text

Does Central Core Disease have a Neuronal Component? by De Crescenzo, Valerie, Fogarty, Kevin E., Bellvé, Karl D., Tuft, Richard A., Zvaritch, Elena, Maclennan, David H., Walsh, John V.

Get full text

Dihydropyridine Receptors and Type 1 Ryanodine Receptors Constitute the Molecular Machinery for Voltage-Induced Ca 2+ Release in Nerve Terminals by De Crescenzo, Valérie, Fogarty, Kevin E., ZhuGe, Ronghua, Tuft, Richard A., Lifshitz, Lawrence M., Carmichael, Jeffrey, Bellvé, Karl D., Baker, Stephen P., Zissimopoulos, S., Lai, F. Anthony, Lemos, José R., Walsh, John V.

“…Ca 2+ stores were studied in a preparation of freshly dissociated terminals from hypothalamic magnocellular neurons. Depolarization from a holding level of −80…”
Get full text