Search Results - "Bellows, D S"

Viral versus cellular BCL-2 proteins by Hardwick, J M, Bellows, D S

“…All gamma herpesviruses and a few other viruses encode at least one homologue of the mammalian cell death inhibitor BCL-2. Gamma herpesviruses are associated…”
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From large networks to small molecules by Sharom, Jeffrey R, Bellows, David S, Tyers, Mike

“…Large-scale analysis of genetic and physical interaction networks has begun to reveal the global organization of the cell. Cellular phenotypes observed at the…”
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An adenosine A1 receptor agonist, R(-)-N-(2-phenylisopropyl)-adenosine (PIA), but not adenosine itself, acts as a therapeutic preconditioning-mimetic agent in rabbits by Hale, S L, Bellows, S D, Hammerman, H, Kloner, R A

“…A preconditioning mimetic agent could be useful therapy for cardiac ischaemic events; stimulation of adenosine receptors has been proposed as a preconditioning…”
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A Bcl-2 Homolog Encoded by Kaposi Sarcoma-Associated Virus, Human Herpesvirus 8, Inhibits Apoptosis but does not Heterodimerize with Bax or Bak by Emily H.-Y. Cheng, Nicholas, John, Bellows, David S., Hayward, Gary S., Guo, Hong-Guang, Reitz, Marvin S., Hardwick, J. Marie

“…The Bcl-2 protein family is characterized by the ability to modulate cell death, and members of this family share two highly conserved domains called Bcl-2…”
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Antiapoptotic Herpesvirus Bcl-2 Homologs Escape Caspase-Mediated Conversion to Proapoptotic Proteins by Bellows, D S, Chau, B N, Lee, P, Lazebnik, Y, Burns, W H, Hardwick, J M

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Epstein-Barr Virus BALF1 Is a BCL-2-Like Antagonist of the Herpesvirus Antiapoptotic BCL-2 Proteins by Bellows, David S, Howell, Melanie, Pearson, Colin, Hazlewood, Sheila A, Hardwick, J Marie

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Do antioxidant vitamins reduce infarct size following acute myocardial ischemia/reperfusion ? by BELLOWS, S. D, HALE, S. L, SIMKHOVICH, B. Z, KAY, G. L, KLONER, R. A

“…There is controversy concerning the ability of antioxidant vitamins to reduce myocardial infarct size. We sought to determine whether a brief prophylactic…”
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Is Warm Retrograde Blood Cardioplegia Better Than Cold for Myocardial Protection? by Kamlot, MD, Andreas, Bellows, BS, Stephen D, Simkhovich, MD, PhD, Boris Z, Hale, BS, Sharon L, Aoki, MD, Atsushi, Kloner, MD, PhD, Robert A, Kay, MD, Gregory L

“…Background. This study tests the hypothesis that continuous normothermic retrograde blood cardioplegia is superior to cold intermittent blood cardioplegia in…”
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BAD Is a Pro-survival Factor Prior to Activation of Its Pro-apoptotic Function by Seo, So Young, Chen, Ying-Bei, Ivanovska, Iva, Ranger, Ann M, Hong, Suk J, Dawson, Valina L, Korsmeyer, Stanley J, Bellows, David S, Fannjiang, Yihru, Hardwick, J Marie

“…The mammalian BAD protein belongs to the BH3-only subgroup of the BCL-2 family. In contrast to its known pro-apoptotic function, we found that endogenous and…”
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Chemical Genetics Hits "Reality" by Bellows, David S., Tyers, Mike

“…The drug discovery equivalent of reality-based television programs is the forward chemical genetic screen, in which cells or extracts are tested against a…”
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Is warm retrograde blood cardioplegia better than cold for myocardial protection? Commentary by KAMLOT, A, BELLOWS, S. D, SIMKHOVICH, B. Z, HALE, S. L, AOKI, A, KLONER, R. A, KAY, G. L, MENASCHE, P

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Glucose-Insulin-Potassium Does Not Reduce Myocardial Infarct Size in an Ischemic/Reperfusion Rabbit Model by Bellows, SD, Kloner, RA

“…While glucose-insulin-potassium (GIK) has been suggested to be cardioprotective, few studies have assessed its effect on anatomic myocardial infarct size in an…”
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Acute Ethanol Does Not Protect Against Ischemic/Reperfusion Injury in Rabbit Myocardium by Bellows, SD, Hale, SL, Kloner, RA

“…Moderate use of alcohol has shown protective effects in coronary artery disease, while excessive use has been associated with cardiomyopathy and hypertension…”
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Stuttering Reperfusion of Ischemic Myocardium Does Not Exacerbate Myocardial Infarction: Evidence Against Lethal Cell Reperfusion Injury in the Rabbit by Alker, KJ, Bellows, SD, Kloner, RA

“…In the clinical setting of acute myocardial infarction, coronary reperfusion may occur intermittently. Whether this intermittent or stuttering reperfusion…”
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