Search Results - "Bellon, Laurent"

Development and preliminary evaluation of a 90 K Axiom® SNP array for the allo-octoploid cultivated strawberry Fragaria × ananassa by Bassil, Nahla V, Davis, Thomas M, Zhang, Hailong, Ficklin, Stephen, Mittmann, Mike, Webster, Teresa, Mahoney, Lise, Wood, David, Alperin, Elisabeth S, Rosyara, Umesh R, Koehorst-vanc Putten, Herma, Monfort, Amparo, Sargent, Daniel J, Amaya, Iraida, Denoyes, Beatrice, Bianco, Luca, van Dijk, Thijs, Pirani, Ali, Iezzoni, Amy, Main, Dorrie, Peace, Cameron, Yang, Yilong, Whitaker, Vance, Verma, Sujeet, Bellon, Laurent, Brew, Fiona, Herrera, Raul, van de Weg, Eric

“…BACKGROUNDA high-throughput genotyping platform is needed to enable marker-assisted breeding in the allo-octoploid cultivated strawberry Fragaria × ananassa…”
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Moieties in an RNA promoter specifically recognized by a viral RNA-dependent RNA polymerase by Siegel, R.W. (Indiana University, Bloomington, IN.), Bellon, L, Beigelman, L, Kao, C.C

“…RNAs 33 nucleotides in length can direct accurate initiation of subgenomic RNA synthesis by the brome mosaic virus RNA-dependent RNA polymerase (RdRp),…”
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Use of DNA, RNA, and chimeric templates by a viral RNA-dependent RNA polymerase: evolutionary implications for the transition from the RNA to the DNA world by Siegel, R.W, Bellon, L, Beigelman, L, Kao, C.C

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Oligonucleotide Mimics for Antisense Therapeutics:  Solution Phase and Automated Solid-Support Synthesis of MMI Linked Oligomers by Morvan, François, Sanghvi, Yogesh S, Perbost, Michel, Vasseur, Jean-Jacques, Bellon, Laurent

“…Antisense oligonucleotides (AOs) have shown great promise as agents for inhibiting gene expression. In principle, AOs interfere in a sequence-specific manner…”
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Development and preliminary evaluation of a 90 K Axiom[R] SNP array for the allo-octoploid cultivated strawberry Fragaria x ananassa by Bassil, Nahla V, Davis, Thomas M, Zhang, Hailong, Ficklin, Stephen, Mittmann, Mike, Webster, Teresa, Mahoney, Lise, Wood, David, Alperin, Elisabeth S, Rosyara, Umesh R, Koehorst-vanc Putten, Herma, Monfort, Amparo, Sargent, Daniel J, Amaya, Iraida, Denoyes, Beatrice, Bianco, Luca, van Dijk, Thijs, Pirani, Ali, Iezzoni, Amy, Main, Dorrie, Peace, Cameron, Yang, Yilong, Whitaker, Vance, Verma, Sujeet, Bellon, Laurent, Brew, Fiona, Herrera, Raul, van de Weg, Eric

“…A high-throughput genotyping platform is needed to enable marker-assisted breeding in the allo-octoploid cultivated strawberry Fragaria x ananassa. Short-read…”
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Morpholino-Linked Ribozymes:  A Convergent Synthetic Approach by Bellon, Laurent, Workman, Christopher, Scherrer, Jon, Usman, Nassim, Wincott, Francine

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Inhibition of hepatitis C virus (HCV)‐RNA–dependent translation and replication of a chimeric HCV poliovirus using synthetic stabilized ribozymes by Macejak, Dennis G., Jensen, Kristi L., Jamison, Sharon F., Domenico, Kristal, Roberts, Elisabeth C., Chaudhary, Nilabh, von Carlowitz, Ira, Bellon, Laurent, Tong, Myron J., Conrad, Andrew, Pavco, Pamela A., Blatt, Lawrence M.

“…Ribozymes are catalytic RNA molecules that can be designed to cleave specific RNA sequences. To investigate the potential use of synthetic stabilized ribozymes…”
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Development and preliminary evaluation of a 90 K Axiom® SNP array for the allo-octoploid cultivated strawberry Fragaria × ananassa by Bassil, Nahla V, Davis, Thomas M, Zhang, Hailong, Ficklin, Stephen, Mittmann, Mike, Webster, Teresa, Mahoney, Lise, Wood, David, Alperin, Elisabeth S, Rosyara, Umesh R, Koehorst-Vanc Putten, Herma, Monfort, Amparo, Sargent, Daniel J, Amaya, Iraida, Denoyes, Beatrice, Bianco, Luca, van Dijk, Thijs, Pirani, Ali, Iezzoni, Amy, Main, Dorrie, Peace, Cameron, Yang, Yilong, Whitaker, Vance, Verma, Sujeet, Bellon, Laurent, Brew, Fiona, Herrera, Raul, van de Weg, Eric

“…A high-throughput genotyping platform is needed to enable marker-assisted breeding in the allo-octoploid cultivated strawberry Fragaria × ananassa. Short-read…”
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Pharmacokinetics and Tissue Distribution of a Ribozyme Directed Against Hepatitis C Virus RNA Following Subcutaneous or Intravenous Administration in Mice by Lee, Patrice A., Blatt, Lawrence M., Blanchard, Karin S., Bouhana, Karyn S., Pavco, Pamela A., Bellon, Laurent, Sandberg, Jennifer A.

“…A nuclease resistant ribozyme targeting the 5′ untranslated region (5′ UTR) of hepatitis C virus (HCV) at site 195 has been identified. To investigate the…”
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Identification and characterization of a novel high affinity metal-binding site in the hammerhead ribozyme by HANSEN, MARK R., SIMORRE, JEAN-PIERRE, HANSON, PAUL, MOKLER, VICTOR, BELLON, LAURENT, BEIGELMAN, LEONID, PARDI, ARTHUR

“…A novel metal-binding site has been identified in the hammerhead ribozyme by 31P NMR. The metal-binding site is associated with the A13 phosphate in the…”
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Pharmacokinetics and Tolerability of an Antiangiogenic Ribozyme (ANGIOZYME™) in Healthy Volunteers by Sandberg, Jennifer A., Parker, Vann P., Blanchard, Karin S., Sweedler, David, Powell, James A., Kachensky, Arlee, Bellon, Laurent, Usman, Nassim, Rossing, Thomas, Borden, Ernest, Blatt, Lawrence M.

“…The pharmacokinetics and tolerability of a chemically stabilized synthetic ribozyme (ANGIOZYME™) targeting the Flt‐1 VEGF receptor mRNA were evaluated in…”
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Oligoribonucleotides with 2'-O-(tert-butyldimethylsilyl) groups by Bellon, L

“…The chemical synthesis of oligoribonucleotides on solid support is routinely performed via the phosphoramidite method. However, the additional 2-OH function of…”
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Morpholino-linked ribozymes: A convergent synthetic approach by Bellon, L, Workman, C, Scherrer, J, Usman, N, Wincott, F

“…Hammerhead ribozymes are naturally occurring self-cleaving RNA enzymes that can be engineered as trans-cleaving molecules. Advances in the solid-phase chemical…”
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Quantitative Determination of a Chemically Modified Hammerhead Ribozyme in Blood Plasma Using 96-Well Solid-Phase Extraction Coupled with High-Performance Liquid Chromatography or Capillary Gel Electrophoresis by Bellon, Laurent, Maloney, Lara, Zinnen, Shawn P., Sandberg, Jennifer A., Johnson, Kevin E.

“…Versatile bioanalytical assays to detect chemically stabilized hammerhead ribozyme and putative ribozyme metabolites from plasma are described. The extraction…”
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4′-Thio-oligo-β-D-ribonucleotides: synthesis of β-4′-thio-oligouridylates, nuclease resistance, base pairing properties, and interaction with HIV-1 reverse transcriptase by Bellon, Laurent, Barascut, Jean-Louis, Maury, Georges, Divita, Gilles, Goody, Roger, Imbach, Jean-Louis

“…We present the synthesis and the study of properties of a new series of modified oligonucleotides, namely 4′-thio-oligo-β-D-ribonucleotides (4′-S-RNA)…”
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Post-synthetically Ligated Ribozymes:  An Alternative Approach to Iterative Solid-Phase Synthesis by Bellon, Laurent, Workman, Christopher T, Jarvis, Thale C, Wincott, Francine E

“…To improve the overall yield of ribozyme synthesis, a convergent approach, based on the post-synthetic formation of an amino linker between two half-ribozymes…”
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Sugar modified oligonucleotides: synthesis, nuclease resistance and base pairing of oligodeoxynucleotides containing 1-(4'-thio-beta-D-ribofuranosyl)-thymine by Bellon, L, Morvan, F, Barascut, J L, Imbach, J L

“…XdT12 and dT5XdT6, where X is 1-(4'-thio-beta-d-ribofuranosyl)-thymine, were synthesized. The first oligonucleotide presents a better stability against calf…”
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Acute toxicology and pharmacokinetic assessment of a ribozyme (ANGIOZYME) targeting vascular endothelial growth factor receptor mRNA in the cynomolgus monkey by Sandberg, J A, Sproul, C D, Blanchard, K S, Bellon, L, Sweedler, D, Powell, J A, Caputo, F A, Kornbrust, D J, Parker, V P, Parry, T J, Blatt, L M

“…The potential acute toxicity of a ribozyme (ANGIOZYME) targeting the flt-1 vascular endothelial growth factor (VEGF) receptor mRNA was evaluated in cynomolgus…”
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4'-Thio-RNA: synthesis of mixed base 4'-thio-oligoribonucleotides, nuclease resistance, and base pairing properties with complementary single and double strand by Leydier, C, Bellon, L, Barascut, J L, Morvan, F, Rayner, B, Imbach, J L

“…4'-Thio-beta-D-oligoribonucleotides (12 mer and 16 mer) containing a mixed base sequence were synthesized via the phosphoramidite solid support approach. These…”
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