Search Results - "Bellocq, N C"

Effects of Structure of β-Cyclodextrin-Containing Polymers on Gene Delivery by Hwang, Suzie J, Bellocq, Nathalie C, Davis, Mark E

“…Linear cationic β-cyclodextrin-based polymers (βCDPs) are capable of forming polyplexes with nucleic acids and transfecting cultured cells. The βCDPs are…”
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Self-assembling nucleic acid delivery vehicles via linear, water-soluble, cyclodextrin-containing polymers by Davis, M E, Pun, S H, Bellocq, N C, Reineke, T M, Popielarski, S R, Mishra, S, Heidel, J D

“…Non-viral (synthetic) nucleic acid delivery systems have the potential to provide for the practical application of nucleic acid-based therapeutics. We have…”
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Transferrin-Containing, Cyclodextrin Polymer-Based Particles for Tumor-Targeted Gene Delivery by Bellocq, Nathalie C, Pun, Suzie H, Jensen, Gregory S, Davis, Mark E

“…Transferrin is a well-studied ligand for tumor targeting due to upregulation of transferrin receptors in numerous cancer cell types. Here, we report the…”
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Cyclodextrin-Modified Polyethylenimine Polymers for Gene Delivery by Pun, Suzie H, Bellocq, Nathalie C, Liu, Aijie, Jensen, Greg, Machemer, Todd, Quijano, Erlinda, Schluep, Thomas, Wen, Shufen, Engler, Heidrun, Heidel, Jeremy, Davis, Mark E

“…Linear and branched poly(ethylenimines), lPEI and bPEI, respectively, grafted with β-cyclodextrin are prepared to give CD−lPEI and CD−bPEI, respectively, and…”
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Synthetic Biocompatible Cyclodextrin-Based Constructs for Local Gene Delivery to Improve Cutaneous Wound Healing by Bellocq, Nathalie C, Kang, David W, Wang, Xuehui, Jensen, Gregory S, Pun, Suzie H, Schluep, Thomas, Zepeda, Monica L, Davis, Mark E

“…The localized, sustained delivery of growth factors for wound healing therapy is actively being explored by gene transfer to the wound site. Biocompatible…”
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Structure−Function Correlation of Chloroquine and Analogues as Transgene Expression Enhancers in Nonviral Gene Delivery by Cheng, Jianjun, Zeidan, Ryan, Mishra, Swaroop, Liu, Aijie, Pun, Suzie H, Kulkarni, Rajan P, Jensen, Gregory S, Bellocq, Nathalie C, Davis, Mark E

“…To understand how chloroquine (CQ) enhances transgene expression in polycation-based, nonviral gene delivery systems, a number of CQ analogues with variations…”
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Targeted delivery of RNA-cleaving DNA enzyme (DNAzyme) to tumor tissue by transferrin-modified, cyclodextrin-based particles by Pun, Suzie H., Tack, Frederik, Bellocq, Nathalie C., Cheng, Jianjun, Grubbs, Brendan H., Jensen, Gregory S., Davis, Mark E., Brewster, Marcus, Janicot, Michel, Janssens, Boudewijn, Floren, Wim, Bakker, Annette

“…Short nucleic acid sequences specific to oncogene targets such as bcl-2, bcr-abl, and c-myc have been shown to exhibit specific anti-cancer activity in vitro…”
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Cyclodextrin-Containing Polymers for Gene Delivery by Davis, Mark E, Bellocq, Nathalie C

“…Cyclodextrin-containing polymers are now being explored as vehicles for delivering nucleic acids into cells. The structures of the cyclodextrin-containing…”
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