Search Results - "Bello, MJ"

Genetic and epigenetic alteration of the NF2 gene in sporadic meningiomas by Lomas, Jesus, Bello, M. Josefa, Arjona, Dolores, Alonso, M. Eva, Martinez-Glez, Victor, Lopez-Marin, Isabel, Amiñoso, Cinthia, de Campos, Jose M., Isla, Alberto, Vaquero, Jesus, Rey, Juan A.

“…The role of the NF2 gene in the development of meningiomas has recently been documented; inactivating mutations plus allelic loss at 22q, the site of this gene…”
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DNA methylation of multiple promoter-associated CpG islands in meningiomas: relationship with the allelic status at 1p and 22q by Bello, M Josefa, Amiñoso, Cinthia, Lopez-Marin, Isabel, Arjona, Dolores, Gonzalez-Gomez, Pilar, Alonso, M Eva, Lomas, Jesus, de Campos, Jose M, Kusak, M Elena, Vaquero, Jesus, Isla, Alberto, Gutierrez, Manuel, Sarasa, Jose L, Rey, Juan A

“…The purpose of this research was to examine the DNA methylation profile of meningiomas. Accordingly, we examined the DNA methylation status of ten…”
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CpG island methylation status and mutation analysis of the RBI gene essential promoter region and protein-binding pocket domain in nervous system tumours by Gonzalez-Gomez, P, Bello, MJ, Alonso, ME, Arjona, D, Lomas, J, De Campos, JM, Isla, A, Rey, JA

“…A series of 136 nervous system tumours were studied to determine the methylation status of the CpG island contained within the promoter region of the RBI gene,…”
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Promoter hypermethylation of multiple genes in astrocytic gliomas by Gonzalez-Gomez, Pilar, Bello, M Josefa, Arjona, Dolores, Lomas, Jesus, Alonso, M Eva, De Campos, Jose M, Vaquero, Jesus, Isla, Alberto, Gutierrez, Manuel, Rey, Juan A

“…Promoter hypermethylation represents a primary mechanism in the inactivation of tumor suppressor genes during tumorigenesis. To determine the frequency and…”
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Aberrant methylation of multiple genes in neuroblastic tumours: relationship with MYCN amplification and allelic status at 1p by Gonzalez-Gomez, P, Bello, M.J, Lomas, J, Arjona, D, Alonso, M.E, Amiñoso, C, Lopez-Marin, I, Anselmo, N.P, Sarasa, J.L, Gutierrez, M, Casartelli, C, Rey, J.A

“…Aberrant hypermethylation occurs in tumour cell CpG islands and is an important pathway for the repression of gene transcription in cancers. We investigated…”
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CpG Island Methylation in Sporadic and Neurofibromatis Type 2-Associated Schwannomas by GONZALEZ-GOMEZ, Pilar, BELLO, M. Josefa, SARASA, Jose L, REY, Juan A, ALONSO, M. Eva, LOMAS, Jesus, ARJONA, Dolores, DE CAMPOS, Jose M, VAQUERO, Jesus, ISLA, Alberto, LASSALETTA, Luis, GUTIERREZ, Manuel

“…Purpose: The purpose of this research was to examine the DNA methylation profile of schwannomas. Experimental Design: We examined the DNA methylation status of…”
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NF2 gene mutations and allelic status of 1p, 14q and 22q in sporadic meningiomas by LEONE, P. E, BELLO, M. J, DE CAMPOS, J. M, VAQUERO, J, SARASA, J. L, PESTANA, A, REY, J. A

“…Formation of meningiomas and their progression to malignancy may be a multi-step process, implying accumulation of genetic mutations at specific loci. To…”
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Contrast ultrasound of the urethra in children by Maté, Alejandro, Bargiela, Amelia, Mosteiro, Sonia, Diaz, Alejandro, Bello, Maria José

“…The aim of this study was to report our experience with transperineal ultrasound in studying the urethra, as a complementary technique to contrast-enhanced…”
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Genetic heterogeneity in supratentorial and infratentorial primitive neuroectodermal tumours of the central nervous system by Inda, M M, Perot, C, Guillaud-Bataille, M, Danglot, G, Rey, J A, Bello, M J, Fan, X, Eberhart, C, Zazpe, I, Portillo, E, Tuñón, T, Martínez-Peñuela, J M, Bernheim, A, Castresana, J S

“…Aims : Medulloblastoma (MB), a kind of infratentorial primitive neuroectodermal tumour (PNET), is the most frequent malignant brain tumour in childhood. In…”
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Molecular analysis of the EGFR gene in astrocytic gliomas: mRNA expression, quantitative-PCR analysis of non-homogeneous gene amplification and DNA sequence alterations by Arjona, D., Bello, M. J., Alonso, M. E., Aminoso, C., Isla, A., De Campos, J. M., Sarasa, J. L., Gutierrez, M., Villalobo, A., Rey, J. A.

“…The epidermal growth factor receptor (EGFR) is a transmembrane glycoprotein with tyrosine kinase activity. This report investigates the presence of mutations,…”
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Aberrant CpG island methylation of multiple genes in ependymal tumors by ALONSO, M. Eva, BELLO, M. Josefa, GONZALEZ-GOMEZ, Pilar, ARJONA, Dolores, DE CAMPOS, Jose M, GUTIERREZ, Manuel, REY, Juan A

“…Aberrant methylation of promoter CpG islands in human genes represents an alternative mechanism for genetic inactivation, and contributes to the development of…”
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Promoter CpG methylation of multiple genes in pituitary adenomas : Frequent involvement of Caspase-8 by JOSEFA BELLO, M, DE CAMPOS, Jose M, ISLA, Alberto, CASARTELLI, Cacilda, REY, Juan A

“…The epigenetic changes in pituitary adenomas were identified by evaluating the methylation status of nine genes (RB1, p14(ARF), p16(INK4a), p73, TIMP-3, MGMT,…”
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Allelic loss at 1p and 19q frequently occurs in association and may represent early oncogenic events in oligodendroglial tumors by Bello, M J, Leone, P E, Vaquero, J, de Campos, J M, Kusak, M E, Sarasa, J L, Pestaña, A, Rey, J A

“…The molecular mechanisms underlying the genesis and progression of oligodendroglial tumors are poorly understood, since only restricted information on loss of…”
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Mutation analysis of the p73 gene in nonastrocytic brain tumours by ALONSO, M. E, BELLO, M. J, GONZALEZ-GOMEZ, P, LOMAS, J, ARJONA, D, DE CAMPOS, J. M, KUSAK, M. E, SARASA, J. L, ISLA, A, REY, J. A

“…Loss of heterozygosity (LOH) involving the distal chromosome 1 p36 region occurs frequently in nonastrocytic brain tumours, but the tumour suppressor gene…”
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Mutational analysis of the DAL-1/4.1B tumour-suppressor gene locus in meningiomas by Martinez-Glez, Victor, Bello, M Josefa, Franco-Hernandez, Carmen, De Campos, Jose M, Isla, Alberto, Vaquero, Jesus, Rey, Juan A

“…The DAL-1/41B gene (differentially expressed in adenocarcinoma of the lung), located in the chromosome 18p11.3 region, belongs to the protein family 4.1…”
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Promoter methylation status of multiple genes in brain metastases of solid tumors by Gonzalez-Gomez, Pilar, Bello, M Josefa, Alonso, M Eva, Amiñoso, Cinthia, Lopez-Marin, Isabel, De Campos, Jose M, Isla, Alberto, Gutierrez, Manuel, Rey, Juan A

“…The aberrant methylation of the CpG island promoter regions acquired by tumor cells is one mechanism for loss of gene function. The high methylation rate for…”
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Real-time quantitative pcr analysis of gene dosages reveals gene amplification in low-grade oligodendrogliomas by ALONSO, M. Eva, BELLO, M. Josefa, REY, Juan A, ARJONA, Dolores, MARTINEZ-GLEZ, Victor, DE CAMPOS, Jose M, ISLA, Alberto, KUSAK, M. Elena, VAQUERO, Jesus, GUTIERREZ, Manuel, SARASA, Jose L

“…Proto-oncogene amplification is an important alteration that is present in about 45% to 50% of high-grade human gliomas. We studied this mechanism in 8 genes…”
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Pancreatic Castleman's disease: MR findings by Soler, Rafaela, Rodríguez, Esther, Bello, María José, Alvarez, Marta

“…Castleman's disease can involve a number of organs/tissues but generally affects the mediastinum. Occurrence of Castleman's disease in the pancreas in either…”
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Magnetic resonance imaging of primary cardiomyopathies by SOLER, Rafaela, RODRIGUEZ, Esther, REMUINAN, Carmen, BELLO, José, DIAZ, Alejandro

“…Cardiomyopathies are diseases of the myocardium of unknown etiology associated with cardiac dysfunction. On the grounds of their morphology and…”
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Molecular analysis of chromosome 1 abnormalities in human gliomas reveals frequent loss of 1p in oligodendroglial tumors by Bello, M J, Vaquero, J, de Campos, J M, Kusak, M E, Sarasa, J L, Saez-Castresana, J, Pestana, A, Rey, J A

“…Alterations of the short arm of chromosome 1 are recurrently found in cytogenetic analysis of malignant gliomas, and deletions of 1p36-p32 region characterize…”
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