Search Results - "Bello, Barbara Del"

Calpain-3 impairs cell proliferation and stimulates oxidative stress-mediated cell death in melanoma cells by Moretti, Daniele, Del Bello, Barbara, Allavena, Giulia, Corti, Alessandro, Signorini, Cinzia, Maellaro, Emilia

“…Calpain-3 is an intracellular cysteine protease, belonging to Calpain superfamily and predominantly expressed in skeletal muscle. In human melanoma cell lines…”
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Trehalose inhibits cell proliferation and amplifies long‐term temozolomide‐ and radiation‐induced cytotoxicity in melanoma cells: A role for autophagy and premature senescence by Allavena, Giulia, Del Bello, Barbara, Tini, Paolo, Volpi, Nila, Valacchi, Giuseppe, Miracco, Clelia, Pirtoli, Luigi, Maellaro, Emilia

“…Cutaneous melanomas frequently metastasize to the brain, with temozolomide (TMZ) plus radiotherapy (RT) offering little control of these lesions. We tested…”
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Autophagy is upregulated in ovarian endometriosis: a possible interplay with p53 and heme oxygenase-1 by Allavena, Giulia, M.S, Carrarelli, Patrizia, Ph.D, Del Bello, Barbara, Ph.D, Luisi, Stefano, M.D., Ph.D, Petraglia, Felice, M.D, Maellaro, Emilia, Ph.D

“…Objective To evaluate the occurrence of the autophagic process in ovarian endometriomas compared with eutopic endometrium of affected women and with normal…”
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The autophagy inducer trehalose stimulates macropinocytosis in NF1-deficient glioblastoma cells by Del Bello, Barbara, Gamberucci, Alessandra, Marcolongo, Paola, Maellaro, Emilia

“…Background Glioblastoma is a highly aggressive brain tumor. A big effort is required to find novel molecules which can cross the blood–brain barrier and…”
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Cisplatin-induced apoptosis inhibits autophagy, which acts as a pro-survival mechanism in human melanoma cells by Del Bello, Barbara, Toscano, Marzia, Moretti, Daniele, Maellaro, Emilia

“…The interplay between a non-lethal autophagic response and apoptotic cell death is still a matter of debate in cancer cell biology. In the present study…”
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Autoantibodies against the autophagic protein microtubule-associated light-chain 3 (LC3): Immunocharacterization of an atypical ANA pattern by Maellaro, Emilia, Terzuoli, Lucia, Bacarelli, Maria Romana, Del Bello, Barbara, Bizzaro, Nicola, Porcelli, Brunetta

“…Autoantibodies to nuclear and cytoplasmic antigens are commonly detected by indirect immunofluorescence (IIF) on HEp-2 cells, and three major staining patterns…”
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Cisplatin/Hydrogel Complex In Cancer Therapy by Casolaro, Mario, Cini, Renzo, Del Bello, Barbara, Ferrali, Marco, Maellaro, Emilia

“…Hydrogels containing α-amino acid residues (l-phenylalanine, l-histidine) were used to complex the chemotherapeutic agent cisplatin. The release of the drug in…”
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Cleavage of Bcl-2 in oxidant- and cisplatin-induced apoptosis of human melanoma cells by DEL BELLO, Barbara, VALENTINI, Marta A, ZUNINO, Franco, COMPORTI, Mario, MAELLARO, Emilia

“…Although the anti-apoptotic effect of Bcl-2 is well established, the role of Bcl-2 in tumour response to therapy and drug resistance is still unclear. The…”
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Hydrogel containing l-valine residues as a platform for cisplatin chemotherapy by Casolaro, Mario, Barbara, Del Bello, Emilia, Maellaro

“…[Display omitted] ► Hydrogels with l-valine residues were synthesized at low degree of crosslinking and loaded with cisplatin with a well-defined…”
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Correction: Cisplatin-Induced Apoptosis Inhibits Autophagy, Which Acts as a Pro-Survival Mechanism in Human Melanoma Cells by Del Bello, Barbara, Toscano, Marzia, Moretti, Daniele, Maellaro, Emilia

“…The correct affiliation is: 1 Department of Pathophysiology, Experimental Medicine and Public Health, University of Siena, Siena, Italy, and Istituto Toscano…”
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Loss of MYC Confers Resistance to Doxorubicin-induced Apoptosis by Preventing the Activation of Multiple Serine Protease- and Caspase-mediated Pathways by Grassilli, Emanuela, Ballabeni, Andrea, Maellaro, Emilia, Del Bello, Barbara, Helin, Kristian

“…c-Myc plays an essential role in proliferation, differentiation, and apoptosis. Because of its relevance to cancer, most studies have focused on the cellular…”
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Calpains and cancer: Friends or enemies? by Moretti, Daniele, Del Bello, Barbara, Allavena, Giulia, Maellaro, Emilia

“…•Calpains proteolyze many substrates, degrading them or modulating their function.•Human calpains comprise ubiquitous and tissue-specific isoforms.•Calpains…”
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Erythrocyte caspase-3 activation and oxidative imbalance in erythrocytes and in plasma of type 2 diabetic patients by Maellaro, Emilia, Leoncini, Silvia, Moretti, Daniele, Del Bello, Barbara, Tanganelli, Italo, De Felice, Claudio, Ciccoli, Lucia

“…An increased oxidative stress and a decreased life span of erythrocytes (RBCs) are reported in patients with diabetes. Aim of this study was to assess in RBCs…”
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Autophagy up-regulation by ulipristal acetate as a novel target mechanism in the treatment of uterine leiomyoma: an in vitro study by Del Bello, Barbara, Marcolongo, Paola, Ciarmela, Pasquapina, Sorbi, Flavia, Petraglia, Felice, Luisi, Stefano, Maellaro, Emilia

“…To assess the effect of ulipristal acetate (UPA) on the autophagic process of uterine leiomyoma cells. In vitro study in primary cultures of leiomyoma and…”
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Long-term doxorubicin release from multiple stimuli-responsive hydrogels based on α-amino-acid residues by Casolaro, Mario, Casolaro, Ilaria, Bottari, Severino, Del Bello, Barbara, Maellaro, Emilia, Demadis, Konstantinos D.

“…Cumulative doxorubicin release (%) from DOXO-loaded magnetic-hydrogels based on α-aminoacid residues (l-phenylalanine and l-valine) under different…”
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Nonbiodegradable expanded polytetrafluoroethylene-covered stent implantation in porcine peripheral arteries : Histologic evaluation of vascular wall response compared with uncoated stents by SANGIORGI, Giuseppe, ARBUSTINI, Eloisa, LANZARINI, Paolo, DEL BELLO, Barbara, MAESTRI, Marcello, GASPARI, Annalisa, SOLCIA, Marco, VIRMANI, Renu, INGLESE, Luigi

“…To test the vascular wall response to an expanded polytetrafluoroethylene-covered stent, compared with conventional stenting, up to 6 months after deployment…”
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Corrigendum to “Hydrogel containing l-valine residues as a platform for cisplatin chemotherapy” [Colloids Surf. B: Biointerf. 88 (2011) 389–395] by Casolaro, Mario, Del Bello, Barbara, Maellaro, Emilia

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Redox modulation of cell surface protein thiols in U937 lymphoma cells: the role of gamma-glutamyl transpeptidase-dependent H2O2 production and S-thiolation by Dominici, S, Valentini, M, Maellaro, E, Del Bello, B, Paolicchi, A, Lorenzini, E, Tongiani, R, Comporti, M, Pompella, A

“…The expression of gamma-glutamyl transpeptidase (GGT), a plasma membrane ectoenzyme involved in the metabolism of extracellular reduced glutathione (GSH), is a…”
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Correction: Cisplatin-Induced Apoptosis Inhibits Autophagy, Which Acts as a Pro-Survival Mechanism in Human Melanoma Cells by Barbara Del Bello, Marzia Toscano, Daniele Moretti, Emilia Maellaro

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Role of caspases-3 and -7 in Apaf-1 proteolytic cleavage and degradation events during cisplatin-induced apoptosis in melanoma cells by Del Bello, Barbara, Valentini, Marta A, Mangiavacchi, Paola, Comporti, Mario, Maellaro, Emilia

“…Apoptosis protease-activating factor-1 (Apaf-1), the central element in the mitochondrial pathway of apoptosis, is frequently absent or poorly expressed in…”
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